Estrasorb

Generic Name: Estradiol

  • What is Estrasorb?

    Estrasorb is a medicine that contains an estrogen hormone called estradiol. It is used after menopause to reduce moderate to severe hot flashes.

  • What is the most important information I should know about Estrasorb?

    Estrogens increase the chances of getting cancer of the uterus. Report any unusual vaginal bleeding right away while you are using Estrasorb. Vaginal bleeding after menopause may be a warning sign of cancer of the uterus (womb). Your healthcare provider should check any unusual vaginal bleeding to find out the cause.

    Do not use estrogens with or without progestins to prevent heart disease, heart attack, stroke, or dementia. Using estrogens with or without progestins may increase your risk of heart attack, stroke, breast cancer, and blood clots. Using estrogens with or without progestins may increase your risk of dementia, based on a study of women age ≥65 years. You and your healthcare provider should talk regularly about whether you still need treatment with Estrasorb.

  • Who should not take Estrasorb?

    Do not take Estrasorb if you are allergic to any of its ingredients. Hormone therapy should not be started if you have unusual vaginal bleeding and if you currently have or have had certain cancers. If you have had cancer, talk with your healthcare provider about whether you should use Estrasorb. Also, do not take this drug if you have had a stroke or heart attack in the past year, currently have or have had blood clots, or think you may be pregnant.

  • What should I tell my doctor before I take the first dose of Estrasorb?

    Tell your doctor about all prescription, over-the-counter, and herbal medications you are taking before beginning treatment with Estrasorb. Also, talk to your doctor about your complete medical history, especially if you have asthma (wheezing), epilepsy (seizures), migraine, endometriosis, lupus, problems with your heart, liver, thyroid, kidneys, or have high calcium levels in your blood.

    Tell your doctor if you are breastfeeding, going to have surgery, or will be on bedrest.

  • What is the usual dosage?

    The information below is based on the dosage guidelines your doctor uses. Depending on your condition and medical history, your doctor may prescribe a different regimen. Do not change the dosage or stop taking your medication without your doctor's approval.

    Adults: The usual dosage of Estrasorb is 3.48 grams (g) (two 1.74-g pouches) daily.

  • How should I take Estrasorb?

    Apply Estrasorb in the morning. If you shower or take a bath, be sure your skin is dry before applying this medication.

    Do not apply Estrasorb to any skin on your thighs and calves that appears to be red or irritated.

    Do not apply sunscreen and Estrasorb at the same time because sunscreen may affect the amount of Estrasorb you absorb.

    Allow the cream to be absorbed before putting on any clothing. Do not open the pouches until just before you apply Estrasorb.

    Estrasorb should be applied in a comfortable sitting position to clean, dry skin on both legs each morning.

    Each foil-laminated pouch of Estrasorb should be opened individually. Cut or tear the first foil-laminated pouch at the notches indicated near the top of the pouch.

    Apply the emulsion in the pouch to the top of the left thigh, being careful to push the entire contents from the bottom through the neck of the pouch. Using one or both hands, rub the emulsion into the entire left thigh and left calf for 3 minutes until thoroughly absorbed. Rub any excess material remaining on both hands on the buttocks.

    Allow the application areas to dry completely before covering with clothing to avoid transfer to other individuals. On completion of Estrasorb application, wash both hands with soap and water to remove any residual estradiol.

  • What should I avoid while taking Estrasorb?

    After applying Estrasorb, avoid coming into contact with other people before washing your hands.

    Avoid applying sunscreen and Estrasorb at the same time because sunscreen may affect the amount of estradiol you absorb.

    Grapefruit and grapefruit juice may increase the risk of Estrasorb's side effects. Talk to your doctor before including grapefruit or grapefruit juice in your diet while you are taking Estrasorb.

  • What are possible food and drug interactions associated with Estrasorb?

    If Estrasorb is taken with certain other drugs, the effects of either could be increased, decreased, or altered. It is especially important to check with your doctor before combining Estrasorb with the following: carbamazepine, clarithromycin, erythromycin, grapefruit juice, itraconazole, ketoconazole, phenobarbital, rifampin, ritonavir, or St. John's wort.

  • What are the possible side effects of Estrasorb?

    Side effects cannot be anticipated. If any develop or change in intensity, tell your doctor as soon as possible. Only your doctor can determine if it is safe for you to continue taking this drug.

    Side effects may include: breast pain, hair loss, headache, irregular vaginal bleeding or spotting, nausea and vomiting, skin irritation/redness/rash, stomach/abdominal cramps/bloating

    Warning signs of serious side effects include: breast lumps, calf or leg swelling, changes in speech, changes in vision, chest pain, depression, dizziness and faintness, fever, memory problems, mental or mood changes, pains in your legs, severe headaches, shortness of breath, unusual vaginal bleeding, vomiting

  • Can I receive Estrasorb if I am pregnant or breastfeeding?

    You should not use Estrasorb if you are pregnant or plan on becoming pregnant due to potential harm to the baby. If you are or will be breastfeeding while using Estrasorb, check with your doctor to discuss any possible risks to your baby.

  • What should I do if I miss a dose of Estrasorb?

    If you miss a dose of Estrasorb, use it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not use two doses at once.

  • How should I store Estrasorb?

    Store Estrasorb at room temperature.

Meet the Pharmacists

I'm Beth Isaac, PharmD. Welcome to PDR Health!

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