What is Etodolac?Etodolac, a nonsteroidal anti-inflammatory drug (NSAID), is used to relieve the inflammation, swelling, stiffness, and joint pain of osteoarthritis and rheumatoid arthritis, as well as for general pain relief. An long-acting formulation is also available.
What is the most important information I should know about Etodolac?Etodolac and other NSAIDs may increase the risk of developing serious life-threatening or fatal heart or circulation problems, such as heart attack and stroke, especially with long-term use. These events may occur without warning signs. Tell your doctor immediately if you experience chest pain, shortness of breath, or weakness.
Etodolac and other NSAIDs can cause stomach discomfort. Rarely, serious ulcers or internal bleeding can occur without warning and result in hospitalization or even death. Tell your doctor immediately if you experience stomach pain, indigestion, or bloody vomit or stools.
Contact your doctor if you experience any changes in your vision, skin rash or blisters with fever, unexplained weight gain or fluid retention, yellowing of your skin or eyes, "flulike" symptoms, difficulty breathing, or swelling of the face or throat while taking Etodolac.
Who should not take Etodolac?If you are sensitive to or have ever had an allergic reaction to Etodolac, or if you have had asthma attacks, hives, or other allergic reactions caused by aspirin or other NSAIDs, you should not take this medication; it might cause a severe allergic reaction.
Do not take Etodolac for the treatment of pain associated with heart bypass surgery.
What should I tell my doctor before I take the first dose of Etodolac?Tell your doctor about all prescription, over-the-counter, and herbal medications you are taking before beginning treatment with Etodolac. Also, talk to your doctor about your complete medical history, especially if you have asthma, heart disease, high blood pressure, fluid retention, kidney or liver disease, anemia, ulcers or internal bleeding, problems with your stomach or digestive system, an infection, or if you smoke or drink alcohol. Also tell your doctor if you are pregnant, plan to become pregnant, or are breastfeeding.
What is the usual dosage?The information below is based on the dosage guidelines your doctor uses. Depending on your condition and medical history, your doctor may prescribe a different regimen. Do not change the dosage or stop taking your medication without your doctor's approval.
General Pain Relief
Adults: Take 200-400 milligrams (mg) every 6-8 hours as needed. Ordinarily, you should not take more than 1,000 mg a day, although your doctor may increase the dose to 1,200 mg a day if absolutely necessary.
Osteoarthritis and Rheumatoid Arthritis
Adults: The starting dose is 300 mg two or three times a day, or 400 mg or 500 mg twice a day. The usual daily maximum ranges from 600-1,000 mg, although your doctor may prescribe as much as 1,200 mg a day if necessary.
How should I take Etodolac?Take this medication exactly as prescribed by your doctor, and at the lowest dose for the shortest possible duration of time. Talk to your doctor before using over-the-counter Etodolac and other NSAIDs for more than 10 days.
The doctor may instruct you to take Etodolac with food or an antacid, and with a full glass of water. Never take it on an empty stomach.
What should I avoid while taking Etodolac?Do not drink alcohol while taking Etodolac. Do not take aspirin or any other anti-inflammatory medications while taking Etodolac, unless your doctor tells you to do so.
What are possible food and drug interactions associated with Etodolac?If Etodolac is taken with certain other drugs, the effects of either could be increased, decreased, or altered. It is especially important to check with your doctor before combining Etodolac with the following: aspirin, blood pressure medications known as angiotensin-converting enzyme (ACE) inhibitors, cyclosporine, digoxin, diuretics (water pills), lithium, methotrexate, phenylbutazone, and warfarin.
What are the possible side effects of Etodolac?Side effects cannot be anticipated. If any develop or change in intensity, tell your doctor as soon as possible. Only your doctor can determine if it is safe for you to continue taking this drug.
Side effects may include: abdominal pain, black stools, blurred vision, chills, constipation, depression, diarrhea, dizziness, fever, gas, increased frequency of urination, indigestion, itching, nausea, nervousness, rash, ringing in the ears, painful or difficult urination, vomiting, weakness
Can I receive Etodolac if I am pregnant or breastfeeding?The effects of Etodolac during pregnancy have not been adequately studied. Do not take Etodolac in the last 3 months of your pregnancy. If you are pregnant or plan to become pregnant, inform your doctor immediately. Etodolac may appear in breast milk and could affect a nursing infant. If this medication is essential to your health, your doctor may advise you to discontinue breastfeeding until your treatment with this medication is finished.
What should I do if I miss a dose of Etodolac?Etodolac is taken on an as-needed basis when you are experiencing pain. If you miss a dose and have pain, take the forgotten dose as soon as you remember. If it is almost time for the next dose, skip the one you missed and go back to your regular schedule. Do not take two doses at once.
How should I store Etodolac?Store at room temperature.
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