Etodolac Extended-Release

Generic Name: Etodolac

  • What is this medication and its most common uses?

    Etodolac ER is a nonsteroidal anti-inflammatory drug (NSAID) used to treat osteoarthritis, rheumatoid arthritis in adults, and juvenile rheumatoid arthritis.

  • What should I know when beginning and continuing on this medication?

    How does this medication work?

    Etodolac ER is an extended release medicine (a type of tablet that releases medicine into your body throughout the day). It works by blocking a substance in your body that is involved in causing inflammation and pain in parts of the body where there is arthritis.

    What are the beneficial effects of this medication and when should I begin to have results?

    What: Etodolac ER has been shown to relieve arthritis symptoms, such as pain, swelling, and stiffness.

    When: Etodolac ER may start to work within 1 week of therapy.

    How do I know it is working?

    You may feel relief in your arthritis symptoms after you start taking etodolac ER. This is a good indicator that the medicine is working. Your healthcare provider may ask you questions to assess how well your symptoms are controlled.

  • What are the possible side effects of this medication?

    The following is not a full list of side effects. Side effects cannot be anticipated. If any develop or change in intensity, tell your healthcare provider as soon as possible. Only your healthcare provider can determine if it is safe for you to continue taking this medication.

    Etodolac ER may increase the chance of a life-threatening heart attack or stroke. The risk of heart attack or stroke may be increased with longer use and in people who have heart disease. Call your healthcare provider right away if you develop chest pain, shortness of breath, weakness, or slurring of your speech while taking etodolac ER.

    Etodolac ER should never be used right before or after a heart surgery called a coronary artery bypass graft (CABG).

    Etodolac ER can cause ulcers and bleeding in the stomach and intestines at any time during treatment. Ulcers and bleeding can be life-threatening and may happen without warning symptoms. The chance of a person getting an ulcer or bleeding increases with longer use, smoking, drinking alcohol, older age, having poor health, and if you are taking medicines called corticosteroids (such as prednisone) or blood thinners (such as warfarin). Call your healthcare provider right away if you develop stomach pain, indigestion, bloody or tarry stools, or you vomit blood while taking etodolac ER.

    More common side effects may include: stomach pain, constipation, diarrhea, upset stomach, gas, nausea, vomiting.

    Less common side effects may include:

    Liver problems with symptoms such as nausea, tiredness, weakness, itching, yellowing of your skin or the whites of your eyes, right upper stomach pain, and flu-like symptoms.

    Serious allergic reactions with symptoms such as skin rash, blisters, fever, itching, trouble breathing, or swelling of your face or throat.

    Etodolac ER may cause high blood pressure, anemia (low red blood cell counts), kidney problems, or unexplained weight gain or swelling.

  • Who should not take this medication?

    Do not take etodolac ER if you are allergic to it or any of its ingredients.

    Do not take etodolac ER if you have had an asthma attack, hives, or other allergic reaction with aspirin or any other NSAID (such as ibuprofen or naproxen).

    Do not take etodolac ER for pain right before or after a heart bypass surgery.

    Do not take etodolac ER during the late stages of your pregnancy.

  • What should I tell my healthcare provider before I take the first dose of this medication?

    Tell your healthcare provider about all prescription, over-the-counter, and herbal medications you are taking before beginning treatment with etodolac ER. Also, talk to your healthcare provider about your complete medical history, especially if you have asthma; high blood pressure; heart failure; kidney or liver problems; a history of ulcers or bleeding in your stomach or intestines; or if you are pregnant, plan to become pregnant, or are breastfeeding.

  • What is the usual dosage?

    The information below is based on the dosage guidelines your healthcare provider uses. Depending on your condition and medical history, your healthcare provider may prescribe a different regimen. Do not change the dosage or stop taking your medication without your healthcare provider's approval.

    Rheumatoid Arthritis and Osteoarthritis

    Adults: The recommended starting dose is 400 to 1000 milligrams once a day.

    Juvenile Rheumatoid Arthritis

    Children 6-16 years: Your healthcare provider will prescribe the appropriate dose for your child based on his/her weight.

  • How should I take this medication?

    Take etodolac ER exactly as prescribed by your healthcare provider. Do not change your dose without first talking to your healthcare provider.

  • What should I avoid while taking this medication?

    Do not take other NSAIDs in combination with etodolac ER without first talking to your healthcare provider.

  • What are the possible food and drug interactions associated with this medication?

    If etodolac ER is taken with certain other drugs, the effects of either could be increased, decreased, or altered. It is especially important to check with your healthcare provider before combining etodolac ER with the following: aspirin, blood pressure/heart medications known as angiotensin-converting enzyme (ACE) inhibitors (such as lisinopril and enalapril), cyclosporine, digoxin, lithium, methotrexate, warfarin, or water pills (such as furosemide or hydrochlorothiazide).

  • May I receive this medication if I am pregnant or breastfeeding?

    Do not take etodolac ER if you are in the late stage of your pregnancy. The effects of etodolac ER during early pregnancy and breastfeeding are unknown. Do not breastfeed while you are taking etodolac ER. Tell your healthcare provider immediately if you are pregnant, plan to become pregnant, or are breastfeeding.

  • What should I do if I miss a dose of this medication?

    If you miss a dose of etodolac ER, take it as soon as you remember. However, if it is almost time for your next dose, skip the one you missed and return to your regular dosing schedule. Do not take two doses at once.

  • How should I store this medication?

    Store at room temperature. Protect from excessive heat and humidity.

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