Excedrin Migraine

Generic Name: Acetaminophen

  • What is Excedrin Migraine?

    Excedrin contains a combination of the active ingredients acetaminophen, aspirin, and caffeine, and is used for the treatment of migraines.

  • What is the most important information I should know about Excedrin Migraine?

    Excedrin should be avoided in children and teenagers who are recovering from chickenpox or flulike symptoms due to the risk of developing a rare, but serious illness known as Reye's syndrome. If your child experiences changes in behavior accompanied by nausea and vomiting, contact your doctor immediately.

    Excedrin contains acetaminophen (the active ingredient in Tylenol). To avoid acetaminophen toxicity, do not take more Excedrin than recommended. Also, talk to your doctor or pharmacist before taking any over-the-counter products that may contain acetaminophen. In addition, do not drink alcohol while taking Excedrin.

    Excedrin contains about as much caffeine as a cup of coffee. You should be cautious in using other products that also contain caffeine. Ingesting too much caffeine may cause nervousness, irritability, sleeplessness, or an increase in your heart rate.

  • Who should not take Excedrin Migraine?

    Do not take Excedrin if you ever had an allergic reaction to acetaminophen, aspirin, or any other pain reliever/fever reducer.

  • What should I tell my doctor before I take the first dose of Excedrin Migraine?

    Tell your doctor about all prescription, over-the-counter, and herbal medications you are taking before beginning treatment with Excedrin. Also, talk to your doctor about your complete medical history, especially if you have a fever or stiff neck, liver or kidney problems, stomach bleeding, heartburn, high blood pressure, heart disease, cirrhosis of the liver, or asthma.

  • What is the usual dosage?

    The information below is based on the dosage guidelines your doctor uses. Depending on your condition and medical history, your doctor may prescribe a different regimen. Do not change the dosage or stop taking your medication without your doctor's approval.

    Adults: The recommended dose is 2 tablets daily. Do not take more than 2 tablets in 24 hours.

    Children <18 years: Ask a doctor.

  • How should I take Excedrin Migraine?

    Take Excedrin with a full glass of water.

  • What should I avoid while taking Excedrin Migraine?

    Avoid taking any over-the-counter products that contain acetaminophen without consulting with your doctor or pharmacist.

    Avoid drinking alcohol while taking Excedrin. Also, avoid other products that contain caffeine.

  • What are possible food and drug interactions associated with Excedrin Migraine?

    If Excedrin is taken with certain other drugs, the effects of either could be increased, decreased, or altered. It is especially important to check with your doctor before combining Excedrin with the following: alcohol, arthritis medications, blood thinners, diabetes medications, gout medications, or any other products that contain aspirin, acetaminophen, or caffeine.

  • What are the possible side effects of Excedrin Migraine?

    Side effects cannot be anticipated. If any develop or change in intensity, tell your doctor as soon as possible. Only your doctor can determine if it is safe for you to continue taking this drug.

    Side effects may include: stomach bleeding, bloody stools, vomiting blood, weakness or fainting, stomach pain, ringing in the ears

  • Can I receive Excedrin Migraine if I am pregnant or breastfeeding?

    The effects of Excedrin during pregnancy and breastfeeding are unknown. Tell your doctor immediately if you are pregnant, plan to become pregnant, or are breastfeeding.

  • What should I do if I miss a dose of Excedrin Migraine?

    Excedrin should only be taken as needed. If you miss a dose and feel symptomatic, take it as soon as you remember. Do not exceed the daily recommended dose.

  • How should I store Excedrin Migraine?

    Store at room temperature.

Meet the Pharmacists

I'm Shereen A. Gharbia, PharmD. Welcome to PDR Health!

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