Generic Name: Bupivacaine

  • What is Exparel?

    Exparel is a local anesthetic administered into the surgical site to act as a painkiller after surgery.

  • What is the most important information I should know about Exparel?

    Since Exparel can cause severe life-threatening side effects, it should be given in a facility where trained personnel and equipment are available to treat people immediately in case toxicity occurs.

    Exparel can cause central nervous system reactions. Tell your doctor if you experience restlessness, anxiety, disorganized speech, lightheadedness, numbness, tingling of your mouth and lips, metallic taste, ringing in your ear, dizziness, blurred vision, shakiness, twitching, depression, or drowsiness.

    Exparel can also affect your heart and cause heart problems or irregular heartbeat. Your doctor will monitor your heart after administering Exparel.

    Exparel can cause allergic reactions or anaphylaxis (a serious and rapid allergic reaction that may result in death if not immediately treated). Tell your doctor immediately or get emergency help if you experience rash, itchiness, difficulty breathing, or swelling of your throat, tongue, or mouth.

  • Who should not take Exparel?

    Your doctor will not administer Exparel to you if you are allergic to it or any of its ingredients.

  • What should I tell my doctor before I take the first dose of Exparel?

    Tell your doctor about all prescription, over-the-counter, and herbal medications you are taking before beginning treatment with Exparel. Also, talk to your doctor about your complete medical history, especially if you have heart, liver, or kidney disease, are pregnant, plan to become pregnant, or are breastfeeding.

  • What is the usual dosage?

    The information below is based on the dosage guidelines your doctor uses. Depending on your condition and medical history, your doctor may prescribe a different regimen. Do not change the dosage or stop taking your medication without your doctor's approval.

    Adults: Your doctor will administer the appropriate dose for you based on your condition.

  • How should I take Exparel?

    Your doctor will administer Exparel to you after your surgery.

  • What should I avoid while taking Exparel?

    Do not miss your scheduled follow-up appointments with your doctor.

  • What are possible food and drug interactions associated with Exparel?

    If Exparel is used with certain other drugs, the effects of either could be increased, decreased, or altered. It is important to tell your doctor about any other medications you are taking.

  • What are the possible side effects of Exparel?

    Side effects cannot be anticipated. If any develop or change in intensity, tell your doctor as soon as possible. Only your doctor can determine if it is safe for you to continue taking this drug.

    Side effects include: back pain, bleeding, constipation, dizziness, drowsiness, fever, headache, itchiness, low blood pressure, muscle spasms, nausea, pain during the procedure, rapid heartbeat, swelling of your legs or arms, trouble sleeping, vomiting

  • Can I receive Exparel if I am pregnant or breastfeeding?

    The effects of Exparel during pregnancy are unknown. Exparel can be found in your breast milk if you receive it during breastfeeding. Tell your doctor immediately if you are pregnant, plan to become pregnant, or are breastfeeding.

  • What should I do if I miss a dose of Exparel?

    Exparel should be given under special circumstances determined by your doctor.

  • How should I store Exparel?

    Your doctor will store this medication for you.