Fabrazyme

Generic Name: Agalsidase Beta

  • What is Fabrazyme?

    Fabrazyme is used to replace the missing enzyme alpha-galactosidase A in people with Fabry disease.

  • What is the most important information I should know about Fabrazyme?

    A registry has been established to monitor and evaluate the long-term effects of Fabrazyme and the progression of Fabry disease.

    People with Fabry disease may have compromised heart function, which may make them more likely to experience severe complications from infusions.

  • Who should not take Fabrazyme?

    Fabrazyme should not be used in children <8 years old, since the safety and efficacy of this drug has not been established in this age group.

  • What should I tell my doctor before I take the first dose of Fabrazyme?

    Tell your doctor about all prescription, over-the-counter, and herbal medications you are taking before beginning treatment with Fabrazyme. Also, talk to your doctor about your complete medical history.

  • What is the usual dosage?

    The information below is based on the dosage guidelines your doctor uses. Depending on your condition and medical history, your doctor may prescribe a different regimen. Do not change the dosage or stop taking your medication without your doctor's approval.

    Adults and children ≥8 years: Your doctor will prescribe the appropriate dose for you.

  • How should I take Fabrazyme?

    Fabrazyme will be given by your doctor.

  • What should I avoid while taking Fabrazyme?

    Fabrazyme should be given every 2 weeks to be effective; do not miss any appointments with your doctor.

  • What are possible food and drug interactions associated with Fabrazyme?

    Drug interaction studies have not been performed with Fabrazyme.

  • What are the possible side effects of Fabrazyme?

    Side effects cannot be anticipated. If any develop or change in intensity, tell your doctor as soon as possible. Only your doctor can determine if it is safe for you to continue taking this drug.

    Side effects may include: allergic reactions, chills, fever, flushing, headache, increased heart rate, diarrhea, muscle pain, body aches, stroke, development of antibodies against the enzyme

    Signs of a severe allergic reaction may include hives, difficulty breathing, and swelling of the throat. If any of these events occur, seek immediate medical attention.

  • Can I receive Fabrazyme if I am pregnant or breastfeeding?

    The effects of Fabrazyme during pregnancy and breastfeeding are unknown. Talk to your doctor if you are pregnant, plan to become pregnant, or are breastfeeding.

  • What should I do if I miss a dose of Fabrazyme?

    Ask your doctor what to do if you miss a dose.

  • How should I store Fabrazyme?

    Your healthcare provider will store Fabrazyme in the refrigerator.

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