Generic Name: Gemifloxacin

  • What is this medication and its most common uses?

    Factive is an antibiotic used to treat adults with bronchitis or pneumonia caused by certain bacteria.

  • What should I know when beginning and continuing on this medication?

    How does this medication work?

    Factive works by stopping the growth of bacteria, thereby treating your infection.

    What are the beneficial effects of this medication and when should I begin to have results?

    What: Factive may help relieve symptoms of bacterial infections and may eliminate the bacteria causing the infection.

    When: Everyone responds differently to treatment, so try to be patient and follow your healthcare provider's directions. It is important that you take Factive exactly as your healthcare provider has prescribed for the full course of treatment, even if your symptoms improve earlier.

    How do I know it is working?

    You may start to notice an improvement in your symptoms. This is a good indicator that your medication is working. Your healthcare provider may ask you questions and order tests to assess how well your infection is being treated.

  • What are the possible side effects of this medication?

    The following is not a full list of side effects. Side effects cannot be anticipated. If any develop or change in intensity, tell your healthcare provider as soon as possible. Only your healthcare provider can determine if it is safe for you to continue taking this medication.

    Factive can cause tendon (tough cords of tissue that connect muscles to bones) problems (such as rupture or swelling). Some tendon problems include pain, swelling, tears, and inflammation of tendons including the back of the ankle (Achilles), shoulder, hand, or other tendon sites. Your risk of tendon problems while taking Factive is higher if you are over 60 years of age; are taking corticosteroids (such as prednisone); or have had a kidney, heart, or lung transplant. Call your healthcare provider right away at the first sign of tendon pain, swelling, or inflammation. Also, get medical help right away if you hear or feel a snap or pop in a tendon area, bruise right after an injury in a tendon area, or are unable to move the affected area or bear weight.

    Factive can cause worsening of myasthenia gravis (a disease characterized by long-lasting fatigue and muscle weakness) symptoms. Call your healthcare provider right away if you develop worsening muscle weakness or breathing problems.

    More common side effects may include: diarrhea, rash, nausea, headache, stomach pain, vomiting, dizziness.

    Less common side effects may include:

    Serious heart rhythm changes, with symptoms such as fast or slow heartbeat, or fainting.

    Serious allergic reactions, with symptoms such as loss of consciousness, tingling swelling of the face, lips, tongue, or throat; rash; trouble breathing or swallowing; or rapid heartbeat.

    Liver damage, with symptoms such as unexplained nausea or vomiting, stomach pain, fever, weakness, tenderness, itching, unusual tiredness, loss of appetite, light color bowel movements, dark colored urine, or yellowing of your skin or the whites of your eyes.

    Central nervous system effects, such as seizures, hallucinations, restlessness, shaking, anxiousness or nervousness, confusion, depression, trouble sleeping, nightmares, lightheadedness, suspiciousness, or suicidal thoughts or actions.

    Damage to the nerves in your arms, hands, legs, or feet, with symptoms such as pain, burning, tingling, numbness, or weakness in any of these areas of your body.

    Watery and bloody stools (with or without stomach cramps and fever), even as late as two or more months after having taken the last dose of Factive.

  • Who should not take this medication?

    Do not take Factive if you are allergic to it, any of its ingredients, or similar antibiotics (such as ciprofloxacin or levofloxacin).

    Do not take Factive to treat viral infections, such as the common cold.

  • What should I tell my healthcare provider before I take the first dose of this medication?

    Tell your healthcare provider about all prescription, over-the-counter, and herbal medications you are taking before beginning treatment with Factive. Also, talk to your healthcare provider about your complete medical history, especially if you have tendon, nerve, joint, bone, kidney, or liver problems; myasthenia gravis; rheumatoid arthritis (a type of arthritis that involves inflammation of the joints); seizures; low blood potassium or magnesium levels; slow heartbeat, or if you or anyone in your family has an irregular heartbeat, especially prolonged QT interval (very fast or abnormal heartbeats).

  • What is the usual dosage?

    The information below is based on the dosage guidelines your healthcare provider uses. Depending on your condition and medical history, your healthcare provider may prescribe a different regimen. Do not change the dosage or stop taking your medication without your healthcare provider's approval.


    Adults: The usual dose is one 320-milligram (mg) tablet a day for 5 days.


    Adults: The usual dose is one 320-mg tablet a day for 5-7 days.

  • How should I take this medication?

    Take Factive exactly as prescribed by your healthcare provider. Do not change your dose or stop taking Factive without first talking to your healthcare provider.

    Take Factive with or without food, at about the same time each day.

    Swallow tablets whole and drink plenty of fluids while you are taking Factive.

    Take Factive either three hours before or two hours after you take any of these medicines: didanosine, sucralfate, antacids, multivitamins, or other medicines or supplements that contain magnesium, aluminum, iron, or zinc.

  • What should I avoid while taking this medication?

    Do not drive, operate machinery, or engage in other activities that require mental alertness or coordination until you know how Factive affects you.

    Do not expose yourself to sunlamps or tanning beds, and try to limit your time in the sun, as Factive can increase your sensitivity to light. If you need to be outdoors, use sunscreen and wear a hat and loose-fitting clothes that protect your skin from the sun.

    Do not skip doses. Skipping doses or not completing the full course of Factive can decrease its effectiveness and can lead to the growth of bacteria that are resistant to the effects of Factive.

  • What are the possible food and drug interactions associated with this medication?

    If Factive is taken with certain other drugs, the effects of either could be increased, decreased, or altered. It is especially important to check with your healthcare provider before combining Factive with the following: antacids containing aluminum or magnesium, antiarrhythmics (such as amiodarone or sotalol), antipsychotics, cisapride, corticosteroids (oral or by injection), didanosine, water pills (such as furosemide or hydrochlorothiazide), erythromycin, iron (ferrous sulfate), multivitamins containing zinc, nonsteroidal anti-inflammatory drugs (NSAIDs) (such as ibuprofen), probenecid, sucralfate, certain antidepressants, or other blood thinners (such as warfarin).

  • May I receive this medication if I am pregnant or breastfeeding?

    The effects of Factive during pregnancy and breastfeeding are unknown. Do not take Factive while breastfeeding. Tell your healthcare provider immediately if you are pregnant, plan to become pregnant, or are breastfeeding.

  • What should I do if I miss a dose of this medication?

    If you miss a dose of Factive, take it as soon as you remember. Do not take more than 1 dose in a 24-hour period.

  • How should I store this medication?

    Store at room temperature.

Meet the Pharmacists

I'm Beth Isaac, PharmD. Welcome to PDR Health!

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