Firazyr

Generic Name: Icatibant

  • What is Firazyr?

    Firazyr is a medicine used to treat sudden attacks of hereditary angioedema (HAE) in adults 18 years and older. HAE is a very rare genetic condition that causes swelling of various parts of the body, including the hands, feet, face, and airway, as well as abdominal (stomach) cramping.

  • What is the most important information I should know about Firazyr?

    If an attack of HAE involves your voicebox in your throat, inject Firazyr immediately, then go to the nearest hospital emergency room. You may need further medical attention.

  • Who should not take Firazyr?

    Do not use Firazyr if you are allergic to it or any of its ingredients.

  • What should I tell my doctor before I take the first dose of Firazyr?

    Tell your doctor about all prescription, over-the-counter, and herbal medications you are taking before beginning treatment with Firazyr. Also, talk to your doctor about your complete medical history, especially if you have any medical conditions, are pregnant, plan to become pregnant, or are breastfeeding.

  • What is the usual dosage?

    The information below is based on the dosage guidelines your doctor uses. Depending on your condition and medical history, your doctor may prescribe a different regimen. Do not change the dosage or stop taking your medication without your doctor's approval.

    Adults: The recommended dose is one 30-milligram (mg) subcutaneous (just below the skin) injection in the stomach area. If response is inadequate, or if symptoms reappear, you can administer additional doses at intervals ≥6 hours. Do not use more than 3 doses in 24 hours.

  • How should I take Firazyr?

    Use Firazyr exactly as prescribed by your doctor. Your doctor will teach you, or a caregiver, how to give Firazyr injection and when to use it. It is important to read the instructions that came with your prescription.

  • What should I avoid while taking Firazyr?

    Firazyr can cause tiredness, drowsiness, and dizziness. Do not drive a car, use machinery, or do anything that needs you to be alert until you know how Firazyr affects you.

  • What are possible food and drug interactions associated with Firazyr?

    If Firazyr is taken with certain other drugs, the effects of either could be increased, decreased, or altered. It is important to check with your doctor before combining Firazyr with any other medication.

  • What are the possible side effects of Firazyr?

    Side effects cannot be anticipated. If any develop or change in intensity, tell your doctor as soon as possible. Only your doctor can determine if it is safe for you to continue taking this drug.

    Side effects may include: bruising, burning, hives, irritation, itching, numbness, pain, pressure, redness, swelling, or warmth at the injection site; dizziness, fever, headache, high enzymes in your blood, nausea, rash

  • Can I receive Firazyr if I am pregnant or breastfeeding?

    The effects of Firazyr during pregnancy and breastfeeding are unknown. Tell your doctor immediately if you are pregnant, plan to become pregnant, or are breastfeeding.

  • What should I do if I miss a dose of Firazyr?

    Firazyr is only used in emergency situations. Do not use it regularly.

  • How should I store Firazyr?

    Store at room temperature in the original carton until ready to use.