What is Floxuridine?Floxuridine is a medicine used for the palliative management (to relieve the discomfort, symptoms, and stress) of cancer of your stomach or intestines that has spread to your liver and cannot be treated with other medications or removed by surgery. Floxuridine is administered intra-arterially (through an artery).
What is the most important information I should know about Floxuridine?Floxuridine can cause severe heart or blood problems. It can cause low white blood cell counts, low platelet (type of blood cells that form clots to help stop bleeding) counts, or low red blood cell counts. Your doctor will monitor your blood cell counts before you start floxuridine and regularly during your treatment. Tell your doctor if you experience bleeding or tiredness.
Floxuridine can cause severe side effects on your stomach or intestines, especially ulceration or bleeding. Floxuridine can also cause inflammation of your esophagus, sores in your mouth or throat, vomiting, or diarrhea. Tell your doctor immediately if you experience any of these problems.
Hair loss can occur while you are receiving floxuridine. This effect is temporary and will eventually go away.
Floxuridine can cause harm to your unborn baby if you receive it during pregnancy. Tell your doctor immediately if you are pregnant or plan to become pregnant. If you are a man, use appropriate contraceptive measures while you are receiving floxuridine.
Who should not take Floxuridine?Your doctor will not administer floxuridine to you if you are allergic to it or any of its ingredients. Also, your doctor will not administer floxuridine to you if you are in a poor nutritional state, have depressed bone marrow function, or have potentially serious infections.
What should I tell my doctor before I take the first dose of Floxuridine?Tell your doctor about all prescription, over-the-counter, and herbal medications you are taking before beginning treatment with floxuridine. Also, talk to your doctor about your complete medical history, especially if you had chemotherapy or high dose of irradiation to your pelvis, have kidney or liver problems, or are pregnant, plan to become pregnant, or are breastfeeding.
What is the usual dosage?The information below is based on the dosage guidelines your doctor uses. Depending on your condition and medical history, your doctor may prescribe a different regimen. Do not change the dosage or stop taking your medication without your doctor's approval.
Adults: Your doctor will prescribe the appropriate dose for you based on your weight.
How should I take Floxuridine?Your doctor will administer floxuridine to you.
Your doctor will tell you how often you should receive floxuridine.
What should I avoid while taking Floxuridine?Do not miss your scheduled appointment to receive floxuridine.
What are possible food and drug interactions associated with Floxuridine?If floxuridine is used with certain other drugs, the effects of either could be increased, decreased, or altered. It is especially important to tell your doctor if you are taking any of the following prior to treatment with floxuridine: medicines that add stress to you, depress your bone marrow function, or interfere with your nutrition.
What are the possible side effects of Floxuridine?Side effects cannot be anticipated. If any develop or change in intensity, tell your doctor as soon as possible. Only your doctor can determine if it is safe for you to continue taking this drug.
Side effects may include: abdominal pain, allergic reactions, bleeding of your stomach or intestines, blood clots, confusion, decreased blood cell counts, diarrhea, fever, hair loss, headache, heart disease, infections, inflammation of your small intestine, injection-site reactions, local redness, loss of appetite, nail changes, nausea, rash, sores in your mouth or throat, tiredness, visual changes, vomiting, weakness
Can I receive Floxuridine if I am pregnant or breastfeeding?Floxuridine can cause harm to your unborn baby if you receive it during pregnancy. The effects of floxuridine while breastfeeding are unknown. Tell your doctor immediately if you are pregnant, plan to become pregnant, or are breastfeeding.
What should I do if I miss a dose of Floxuridine?Contact your doctor if you miss your scheduled appointment to receive floxuridine.
How should I store Floxuridine?Your doctor will store this medication for you.