Generic Name: Fludrocortisone

  • What is this medication and its most common uses?

    Fludrocortisone is a medicine used to treat Addison's disease (adrenal gland failure) and a disorder of the adrenal gland where sodium (salt) is lost from the body.

  • What should I know when beginning and continuing on this medication?

    How does this medication work?

    Fludrocortisone works by decreasing the amount of sodium your body loses.

    What are the beneficial effects of this medication and when should I begin to have results?

    What: Fludrocortisone may help to relieve symptoms associated with Addison's disease, as well as other adrenal gland disorders.

    When: Everyone responds differently to treatment, so try to be patient and follow your healthcare provider's directions. It is important that you take fludrocortisone exactly as your healthcare provider has prescribed.

    How do I know it is working?

    You may feel an improvement in your symptoms once you begin taking fludrocortisone. This is a good indicator that your medication is working. Your healthcare provider may ask you questions to assess how well your symptoms are controlled.

  • What are the possible side effects of this medication?

    The following is not a full list of side effects. Side effects cannot be anticipated. If any develop or change in intensity, tell your healthcare provider as soon as possible. Only your healthcare provider can determine if it is safe for you to continue taking this medication.

    More common side effects may include: high blood pressure.

    Less common side effects may include:

    Eye problems, such as glaucoma (high pressure in the eye), cataracts, or an infection.

    Fludrocortisone may also cause salt and water retention or decreased blood potassium levels in your body, or may increase your risk of developing an infection.

  • Who should not take this medication?

    Do not take fludrocortisone if you are allergic to it or any of its ingredients.

    Do not take fludrocortisone if you have certain infections.

  • What should I tell my healthcare provider before I take the first dose of this medication?

    Tell your healthcare provider about all prescription, over-the-counter, and herbal medications you are taking before beginning treatment with fludrocortisone. Also, talk to your healthcare provider about your complete medical history, especially if you have heart, kidney, liver, or thyroid problems; high blood pressure; any type of infection (including tuberculosis [a bacterial infection that affects the lungs]); recently been near anyone with chickenpox or measles; stomach or intestinal problems (such as an ulcer or ulcerative colitis); psychiatric conditions (such as mood swings or personality changes); osteoporosis (thin, weak bones); or myasthenia gravis (a disease characterized by long-lasting fatigue and muscle weakness).

  • What is the usual dosage?

    The information below is based on the dosage guidelines your healthcare provider uses. Depending on your condition and medical history, your healthcare provider may prescribe a different regimen. Do not change the dosage or stop taking your medication without your healthcare provider's approval.

    Addison's Disease

    Adults: The usual dose is 0.1 milligrams (mg) once a day. Your healthcare provider may adjust your dose as needed.

    Salt-Losing Adrenal Gland Disorder

    Adults: The usual dose is 0.1 to 0.2 mg once a day.

  • How should I take this medication?

    Take fludrocortisone exactly as prescribed by your healthcare provider. Do not change your dose or stop taking fludrocortisone without first talking to your healthcare provider.

  • What should I avoid while taking this medication?

    Do not come in contact with anyone who has chickenpox or measles while you are taking fludrocortisone.

    Do not receive certain vaccines while you are taking fludrocortisone without first talking to your healthcare provider.

  • What are the possible food and drug interactions associated with this medication?

    If fludrocortisone is taken with certain other drugs, the effects of either could be increased, decreased, or altered. It is especially important to check with your healthcare provider before combining fludrocortisone with the following: amphotericin B, anabolic steroids (such as methandrostenolone, norethandrolone, or oxymetholone), aspirin, barbiturates (such as phenobarbital), blood thinners (such as warfarin), certain water pills (such as ethacrynic acid or furosemide), diabetes medicine (such as insulin), digoxin, estrogen, phenytoin, rifampin, or vaccines.

  • May I receive this medication if I am pregnant or breastfeeding?

    The effects of fludrocortisone during pregnancy are unknown. Fludrocortisone can be found in your breast milk if you take it while breastfeeding. Tell your healthcare provider immediately if you are pregnant, plan to become pregnant, or are breastfeeding.

  • What should I do if I miss a dose of this medication?

    If you miss a dose of fludrocortisone, take it as soon as you remember. However, if it is almost time for your next dose, skip the one you missed and return to your regular dosing schedule. Do not take two doses at once.

  • How should I store this medication?

    Store at room temperature. Protect from excessive heat.