What is Foscarnet?Foscarnet is used to treat cytomegalovirus (CMV) retinitis in people with AIDS. It is also used to treat herpes simplex virus (HSV) in people with a weak immune system.
What is the most important information I should know about Foscarnet?Kidney damage may occur while receiving Foscarnet injection. Seizures have also been reported along with changes in blood levels of electrolytes. Mineral and electrolyte supplements may be required.
Who should not take Foscarnet?You should not receive Foscarnet if you are allergic to any of its ingredients.
What should I tell my doctor before I take the first dose of Foscarnet?Before taking the first dose of Foscarnet, tell your doctor about all the medicines you take, including prescription and nonprescription drugs, vitamins, and herbal supplements. Tell your doctor about your complete medical history, especially if you have ever had seizures, kidney problems, heart disease, a nerve disorder, or an electrolyte imbalance such as low calcium, potassium, or magnesium.
What is the usual dosage?The information below is based on the dosage guidelines your doctor uses. Depending on your condition and medical history, your doctor may prescribe a different regimen. Do not change the dosage or stop taking your medication without your doctor's approval.
Adults: The recommended initial dose in people with normal kidney function is either 90 milligrams (mg)/kilogram (kg) every 12 hours (1.5- to 2-hour infusion), or 60 mg/kg (minimum of 1-hour infusion) every 8 hours over 2 to 3 weeks, depending on clinical response.
Herpes Simplex Virus
Adults: The recommended initial dose in people with normal kidney function is 40 mg/kg (minimum 1-hour infusion) either every 8 or 12 hours for 2 to 3 weeks, or until healed.
How should I take Foscarnet?This drug is an infusion that will be given by your doctor.
What should I avoid while taking Foscarnet?Foscarnet must be given regularly to be effective; do not miss any appointments with your doctor.
What are possible food and drug interactions associated with Foscarnet?If Foscarnet is taken with certain drugs, the effects of either could be increased, decreased, or altered. It is especially important to check with your doctor before combining Foscarnet with the following: intravenous pentamidine, drugs that influence serum calcium concentrations, drugs that affect kidney function, aminoglycosides, amphotericin B, ritonavir, and saquinavir.
What are the possible side effects of Foscarnet?Side effects cannot be anticipated. If any develop or change in intensity, tell your doctor as soon as possible. Only your doctor can determine if it is safe for you to continue taking this drug.
Side effects may include: fever, nausea, vomiting, anemia, diarrhea, abnormal kidney function, headache, seizures
Can I receive Foscarnet if I am pregnant or breastfeeding?The effects of Foscarnet during pregnancy and breastfeeding are unknown. Tell your doctor if you are pregnant, plan to become pregnant, or are breastfeeding.
What should I do if I miss a dose of Foscarnet?Ask your doctor what to do if you miss a dose.
How should I store Foscarnet?Your healthcare provider will store this drug at room temperature.