What is Fosrenol?Fosrenol is a medicine used to reduce blood phosphate levels in people with end-stage renal disease (when the kidneys stop working well enough for you to live without dialysis or a transplant).
What is the most important information I should know about Fosrenol?Fosrenol can cause a bowel blockage or severe constipation that can be serious, and sometimes can lead to surgery or treatment in a hospital. Your risk can increase if you have a history of bowel surgery, colon cancer, bowel blockage, decreased bowel movement, constipation, or diabetes. Tell your doctor if you experience constipation or your constipation gets worse during treatment. Chewing the tablet completely can reduce the risk of these side effects.
Follow-up with your doctor regularly to monitor your blood phosphate levels while you are taking Fosrenol.
Who should not take Fosrenol?Do not take Fosrenol if you are allergic to it or any of its ingredients, or if you have blocked bowels or severe constipation.
What should I tell my doctor before I take the first dose of Fosrenol?Tell your doctor about all prescription, over-the-counter, and herbal medications you are taking before beginning treatment with Fosrenol. Also, talk to your doctor about your complete medical history, especially if you have a history of bowel surgery, colon cancer, bowel blockage, ileus (obstruction of the intestines) or constipation, or diabetes; have stomach ulcers, ulcerative colitis (inflammation of the lower bowel), or Crohn's disease (inflammatory disease of the digestive system); plan to have an x-ray of your abdomen; or are pregnant, plan to become pregnant, or are breastfeeding.
What is the usual dosage?The information below is based on the dosage guidelines your doctor uses. Depending on your condition and medical history, your doctor may prescribe a different regimen. Do not change the dosage or stop taking your medication without your doctor's approval.
Adults: The recommended starting dose is 1500 milligrams (mg) a day, in divided doses. Your doctor may adjust your dose based on your blood phosphate levels.
How should I take Fosrenol?Take Fosrenol exactly as prescribed by your doctor. You can take Fosrenol with or right after meals. Chew the tablets completely before swallowing. If you cannot chew the tablets completely or if you have tooth disease, you can crush the tablets thoroughly before swallowing.
If you take an aluminum-, calcium-, or magnesium-containing antacid, or a thyroid medicine (such as levothyroxine), take the antacid or thyroid medicine 2 hours before or 2 hours after you take Fosrenol. Also, if you take certain oral antibiotics (such as ciprofloxacin or tetracycline), take the antibiotic 1 hour before or 4 hours after you take Fosrenol.
What should I avoid while taking Fosrenol?Do not swallow Fosrenol tablets whole.
What are possible food and drug interactions associated with Fosrenol?If Fosrenol is taken with certain other drugs, the effects of either could be increased, decreased, or altered. It is especially important to check with your doctor before combining Fosrenol with the following: aluminum-, calcium-, or magnesium-containing antacids, certain oral antibiotics, or levothyroxine.
What are the possible side effects of Fosrenol?Side effects cannot be anticipated. If any develop or change in intensity, tell your doctor as soon as possible. Only your doctor can determine if it is safe for you to continue taking this drug.
Side effects may include: abdominal pain, allergic skin reactions, constipation, diarrhea, indigestion, low blood phosphate levels, nausea, tooth injury, vomiting
Can I receive Fosrenol if I am pregnant or breastfeeding?The effects of Fosrenol during pregnancy and breastfeeding are unknown. Tell your doctor immediately if you are pregnant, plan to become pregnant, or are breastfeeding.
What should I do if I miss a dose of Fosrenol?If you miss a dose of Fosrenol, take it as soon as you remember. However, if it is almost time for your next dose, skip the one you missed and return to your regular dosing schedule. Do not take two doses at once.
How should I store Fosrenol?Store at room temperature. Protect from moisture.