Fuzeon

Generic Name: Enfuvirtide

  • What is Fuzeon?

    Fuzeon is a medicine used to treat HIV (human immunodeficiency virus) infection (AIDS) in combination with other anti-HIV medications. Fuzeon is a type of HIV medicine called an HIV fusion inhibitor. It works by lowering the amount of HIV in your blood and increasing the number of certain immune cells to help fight infection. Fuzeon is administered subcutaneously (just below the skin).

  • What is the most important information I should know about Fuzeon?

    You have to take Fuzeon with other HIV medicines, as prescribed by your doctor.

    Always stay on continuous HIV therapy to control your HIV infection and decrease HIV-related illnesses. Though Fuzeon can slow the progress of HIV, it is not a cure. You may continue to develop infections and other complications associated with HIV.

    Fuzeon does not reduce your risk of passing HIV/AIDS to others through sexual contact, sharing needles, or being exposed to your blood. Always practice safe sex to reduce the risk of transmitting HIV to others. Use latex or polyurethane condoms to lower the chance of sexual contact with any body fluids (such as semen, vaginal secretions, or blood).

    Fuzeon can cause pain, discomfort, hardened skin, redness, swelling, bumps, itching, or bruising at the injection site. Tell your doctor immediately if you notice signs of an infection at the injection site (such as oozing, increasing heat, swelling, redness, or pain).

    Inject Fuzeon into your upper arm, abdomen, or thigh. Do not inject this medication near areas where large nerves are close to the skin (such as your elbow, knee, or groin) to prevent the occurrence of prolonged shooting nerve pain and tingling.

    Fuzeon can cause lung infections. Your risk can increase with the severity of your HIV infection, if you are an intravenous drug abuser or a smoker, or if you have a history of lung disease. Tell your doctor immediately if you have a cough with fever, rapid breathing, or shortness of breath.

    Fuzeon can cause serious allergic reactions. Tell your doctor immediately if you develop a rash, fever, nausea and vomiting, chills, rigors, low blood pressure, trouble breathing, blood in your urine, or swelling of your feet.

  • Who should not take Fuzeon?

    Do not use Fuzeon if you are allergic to it or any of its ingredients.

  • What should I tell my doctor before I take the first dose of Fuzeon?

    Tell your doctor about all prescription, over-the-counter, and herbal medications you are taking before beginning treatment with Fuzeon. Also, talk to your doctor about your complete medical history, especially if you have a blood clotting disorder, have a history of lung disease, are a drug abuser or smoker, are pregnant, plan to become pregnant, or are breastfeeding.

  • What is the usual dosage?

    The information below is based on the dosage guidelines your doctor uses. Depending on your condition and medical history, your doctor may prescribe a different regimen. Do not change the dosage or stop taking your medication without your doctor's approval.

    Adults: The recommended dose is 90 milligrams (mg) twice a day.

    Children and adolescents 6-16 years: Your doctor will prescribe the appropriate dose for your child, based on their weight.

  • How should I take Fuzeon?

    Use Fuzeon exactly as prescribed by your doctor. You can use Fuzeon with or without food. Your doctor will instruct you on how to properly inject Fuzeon subcutaneously. Please review the instructions that came with your prescription on how to properly prepare and administer Fuzeon.

    When your Fuzeon supply starts to run low, get more from your doctor or pharmacy. It is important that you do not run out of Fuzeon. If you stop the medicine for even a short time, the amount of HIV in your body can increase or it can become resistant to the effects of Fuzeon.

  • What should I avoid while taking Fuzeon?

    Do not become pregnant or breastfeed while you are using Fuzeon. If you do become pregnant, tell your doctor immediately.

    Do not reuse or share needles or other injection equipment. Also, do not share personal items that can have blood or bodily fluids on them (such as toothbrushes or razor blades).

    Do not have unprotected sex.

    Do not drive or operate heavy machinery if Fuzeon makes you feel dizzy.

  • What are possible food and drug interactions associated with Fuzeon?

    No significant interactions have been reported with Fuzeon at this time. However, always tell your doctor about any medicines you take, including over-the-counter medications, vitamins, and herbal supplements.

  • What are the possible side effects of Fuzeon?

    Side effects cannot be anticipated. If any develop or change in intensity, tell your doctor as soon as possible. Only your doctor can determine if it is safe for you to continue taking this drug.

    Side effects may include: abdominal pain, allergic reactions, constipation, cough, depression, diarrhea, inflammation of your sinus, injection-site reactions, loss of sleep, lung infection, muscle pain, nausea, pain and numbness in your feet or legs, tiredness, weakness, weight loss

  • Can I receive Fuzeon if I am pregnant or breastfeeding?

    The effects of Fuzeon during pregnancy and breastfeeding are unknown. It is recommended that you do not breastfeed your baby if you are infected with HIV. This is because your baby could become infected with HIV through your breast milk. Tell your doctor immediately if you are pregnant, plan to become pregnant, or are breastfeeding.

  • What should I do if I miss a dose of Fuzeon?

    If you miss a dose of Fuzeon, inject it as soon as you remember. However, if it is almost time for your next dose, skip the one you missed and return to your regular dosing schedule. Do not inject two doses at once.

  • How should I store Fuzeon?

    Store at room temperature. After mixing, the solution should be stored in the original vial in a refrigerator and should be used within 24 hours.