Genotropin

Generic Name: Somatropin

  • What is Genotropin?

    Genotropin is an injectable synthetic human growth hormone used in both adults and children. It is used as a replacement for natural growth hormone in adults with growth hormone deficiency (GHD), and for the treatment of children with growth failure due to GHD, Prader-Willi syndrome, Turner syndrome, idiopathic short stature, and those that were born small for gestational age.

  • What is the most important information I should know about Genotropin?

    Intracranial hypertension, a rare and reversible condition of high pressure in the skull, has occurred in patients within the first 8 weeks of Genotropin therapy. Tell your doctor if you or your child experience swelling of the optic disk of the eye, visual changes, headache, nausea, or vomiting while using Genotropin.

  • Who should not take Genotropin?

    Do not take Genotropin if you are allergic to somatropin or any of its components.

    Do not take Genotropin if you have respiratory failure, active tumors, diabetes-associated eye disease, or complications following open heart surgery, abdominal surgery, or multiple accidental traumas.

    Do not use Genotropin to promote growth in pediatric patients with closed epiphyses.

    Prader-Willi Syndrome patients who are severely obese, have a history of upper airway obstruction or sleep apnea, or have severe respiratory impairment should not take Genotropin.

  • What should I tell my doctor before I take the first dose of Genotropin?

    Tell your doctor about all prescription, over-the-counter, and herbal medications you are taking before beginning treatment with Genotropin. Also, talk to your doctor about your complete medical history, especially if you have a history of open heart surgery, abdominal surgery, multiple accidental traumas, tumors, respiratory failure, multiple pituitary hormone deficiencies, low levels of thyroid hormone in the blood, endocrine (hormonal) disorders, scoliosis, ear infections or disorders, or a family history of diabetes.

  • What is the usual dosage?

    The information below is based on the dosage guidelines your doctor uses. Depending on your condition and medical history, your doctor may prescribe a different regimen. Do not change the dosage or stop taking your medication without your doctor's approval.

    Growth Hormone Deficiency

    Adults: Your doctor will prescribe the appropriate dosage for you.

    Children: The recommended dose is 0.16-0.24 milligrams (mg) per 2.2 pounds of body weight per week.

    Idiopathic Short Stature

    Children: The recommended dose is up to 0.47 mg per 2.2 pounds of body weight per week.

    Prader-Willi Syndrome

    Children: The recommended dose is 0.24 mg per 2.2 pounds of body weight per week.

    Small for Gestational Age

    Children: The recommended dose is up to 0.48 mg per 2.2 pounds of body weight per week.

    Turner Syndrome

    Children: The recommended dose is 0.33 mg per 2.2 pounds of body weight per week.

  • How should I take Genotropin?

    Use Genotropin only if the solution is clear and colorless. Follow the directions for reconstitution provided with each device. Do not shake.

    Inject Genotropin under the skin (subcutaneously) into the thigh, buttocks, or abdomen, making sure to rotate the sites of injection daily to avoid injection-site reactions such as redness or pain.

    You and/or your caregiver should be instructed on the injection technique as well as proper syringe and needle disposal.

  • What should I avoid while taking Genotropin?

    Avoid injecting into the same site within 7 days.

  • What are possible food and drug interactions associated with Genotropin?

    If Genotropin is taken with certain other drugs, the effects of either could be increased, decreased, or altered. It is especially important to check with your doctor before combining Genotropin with the following: anticonvulsants, corticosteroids, cyclosporine, glucocorticoid therapy, insulin and other oral diabetes drugs, oral estrogen, or sex steroids.

  • What are the possible side effects of Genotropin?

    Side effects cannot be anticipated. If any develop or change in intensity, tell your doctor as soon as possible. Only your doctor can determine if it is safe for you to continue taking this drug.

    Side effects may include: joint pain, swelling, fluid retention, stiffness

  • Can I receive Genotropin if I am pregnant or breastfeeding?

    The effects of Genotropin during pregnancy and breastfeeding are unknown. Tell your doctor immediately if you are pregnant, plan to become pregnant, or are breastfeeding.

  • What should I do if I miss a dose of Genotropin?

    If you miss a dose of Genotropin, take the missed dose as soon as you remember it. However, if it is almost time for your next dose, skip the one you missed and return to your regular dosing schedule. Do not take two doses at once. If you are unsure, ask your doctor or pharmacist for advice.

  • How should I store Genotropin?

    Store Genotropin powder in the refrigerator prior to reconstitution; it may be stored in the refrigerator for up to 28 days following reconstitution. Do not freeze. Protect from light.

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I'm Kristen Dore, PharmD. Welcome to PDR Health!

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