Humalog

Generic Name: Insulin Lispro

  • What is this medication and its most common uses?

    Humalog is a rapid-acting insulin that is used to control high blood sugar in people with diabetes. Humalog comes as a prefilled pen, vial, and a cartridge.

  • What should I know when beginning and continuing on this medication?

    How does this medication work?

    Your body needs insulin to turn sugar into energy. Diabetes develops when your body does not make enough insulin or does not properly use the insulin it makes. Humalog may help control your blood sugar levels by allowing blood sugar to move from your bloodstream into your cells for energy.

    What are the beneficial effects of this medication and when should I begin to have results?

    What: Lowering your blood sugar to a normal level may prevent or delay potential complications associated with diabetes, such as blindness, kidney failure, or heart problems. Humalog works by covering your meal time insulin needs, when your blood sugar levels rise quickly. Using mealtime insulin in combination with a long- or intermediate-acting insulin will help you to balance out your blood sugar throughout the day.

    When: Humalog will work quickly and may manage your blood sugar at mealtime.

    How do I know it is working?

    Check your blood sugar regularly and as your healthcare provider tells you to. Your healthcare provider will also do regular blood tests to measure your blood sugar levels and your hemoglobin A1C (measures your average blood sugar levels over a 2- to 3-month period). Stay on your prescribed diet and exercise program, as this will also affect the results of your blood tests.

  • What are the possible side effects of this medication?

    The following is not a full list of side effects. Side effects cannot be anticipated. If any develop or change in intensity, tell your healthcare provider as soon as possible. Only your healthcare provider can determine if it is safe for you to continue taking this medication.

    More common side effects may include: low blood sugar, injection-site reactions (including redness, pain, itching, hives, or swelling).

    Symptoms of low blood sugar may include: anxiety, restlessness, trouble concentrating, changes in your personality or mood, blurred vision, dizziness, shakiness, lightheadedness, drowsiness, nightmares or trouble sleeping, sweating, irritability, headache, slurred speech, fast heartbeat, unsteady walking, or tingling in your hands, feet, lips, or tongue.

    Less common side effects may include: low potassium levels in your blood, swelling of your hands and feet, weight gain, skin thickening at the injection site.

    Serious allergic reactions with symptoms such as a rash all over your body, shortness of breath, trouble breathing, fast heartbeat, sweating, or lightheadedness.

  • Who should not take this medication?

    Do not use Humalog if you are allergic to it or any of its ingredients.

  • What should I tell my healthcare provider before I take the first dose of this medication?

    Tell your healthcare provider about all prescription, over-the-counter, and herbal medications you are taking before beginning treatment with Humalog. Also, talk to your healthcare provider about your complete medical history, especially if you have kidney or liver problems, or are pregnant, plan to become pregnant, or are breastfeeding.

  • What is the usual dosage?

    The information below is based on the dosage guidelines your healthcare provider uses. Depending on your condition and medical history, your healthcare provider may prescribe a different regimen. Do not change the dosage or stop taking your medication without your healthcare provider's approval.

    Adults and children ≥3 years: Your healthcare provider will determine your dose based on your blood sugar levels.

  • How should I take this medication?

    Inject Humalog exactly as prescribed by your healthcare provider. Use the proper injection technique taught to you by your healthcare provider. Read the User Manual that comes with your Humalog Prefilled Pen for detailed instructions.

    Inject Humalog within 15 minutes before eating or right after eating a meal. Inject Humalog under the skin of your stomach area, upper arm, upper leg, or buttocks. Never inject Humalog into a muscle or vein. Change your injection site with each dose.

    Only use Humalog that is clear and colorless. If you see that Humalog is cloudy or slightly colored, return it to your pharmacy for a replacement.

  • What should I avoid while taking this medication?

    Do not use Humalog if you do not plan to eat right after your injection or bolus pump infusion.

    Do not drink alcohol while using Humalog. Alcohol may affect your blood sugar.

    Do not drive or operate machinery if you have trouble paying attention or have slower reaction times if you have low blood sugar.

    Do not mix Humalog with any other insulins other than NPH in the same syringe and do not mix Humalog in an insulin pump.

  • What are the possible food and drug interactions associated with this medication?

    If Humalog is used with certain other drugs, the effects of either could be increased, decreased, or altered. Humalog may interact with numerous medications. Therefore, it is very important that you tell your healthcare provider about any other medications you are taking.

  • May I receive this medication if I am pregnant or breastfeeding?

    The effects of Humalog during pregnancy and breastfeeding are unknown. Tell your healthcare provider immediately if you are pregnant, plan to become pregnant, or are breastfeeding.

  • What should I do if I miss a dose of this medication?

    It is very important to follow your insulin regimen exactly as prescribed by your healthcare provider. Do not miss any doses. Ask your healthcare provider for specific instructions to follow in case you ever miss a dose of insulin.

  • How should I store this medication?

    Store unopened Humalog in the refrigerator (not the freezer). Protect from extreme heat, cold, or light.

    After you open Humalog vials, store them in the refrigerator or at room temperature for 28 days.

    After you start using Humalog cartridges or prefilled pens, do not refrigerate them. Keep them at room temperature, away from direct heat and light for up to 28 days.

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