Hycamtin Injection

Generic Name: Topotecan

  • What is Hycamtin Injection?

    Hycamtin injection is a medicine used to treat metastatic cancer of the ovary, lung (small cell) cancer, or recurrent or persistent cervical cancer after other treatments did not work. Hycamtin injection is administered intravenously (through a vein in your arm).

  • What is the most important information I should know about Hycamtin Injection?

    Hycamtin injection decreases your blood cell counts (such as white blood cells, platelets [type of blood cells that form clots to help stop bleeding], and red blood cells). Tell your doctor immediately if you develop a fever, other signs of infection (such as chills, cough, or burning pain on urination), or bleeding while on Hycamtin injection therapy.

    Your doctor will perform frequent blood tests while you are receiving Hycamtin injection to monitor your blood counts.

    Use effective birth control measures to prevent pregnancy and do not breastfeed during treatment with Hycamtin injection.

    Hycamtin injection can cause tiredness or weakness. If these symptoms occur, do not drive or operate machinery.

  • Who should not take Hycamtin Injection?

    Your doctor will not administer Hycamtin injection to you if you are allergic to it, any of its ingredients, or if you are pregnant, breastfeeding, or have low blood cell counts.

  • What should I tell my doctor before I take the first dose of Hycamtin Injection?

    Tell your doctor about all prescription, over-the-counter, and herbal medications you are taking before beginning treatment with Hycamtin injection. Also, talk to your doctor about your complete medical history, especially if you have or have a history of low blood cell counts, colitis (inflammation of the colon), lung disease, are pregnant, plan to become pregnant, or are breastfeeding.

  • What is the usual dosage?

    The information below is based on the dosage guidelines your doctor uses. Depending on your condition and medical history, your doctor may prescribe a different regimen. Do not change the dosage or stop taking your medication without your doctor's approval.

    Adults: Your doctor will administer the appropriate dose for you based on your height, weight, and type of cancer.

    If you have kidney impairment, your doctor will adjust your dose appropriately.

  • How should I take Hycamtin Injection?

    Your doctor will administer Hycamtin injection as an intravenous infusion over 30 minutes.

  • What should I avoid while taking Hycamtin Injection?

    Do not become pregnant or breastfeed while being treated with Hycamtin injection.

    Do not drive or operate heavy machinery if you feel tired or weak while on Hycamtin injection therapy.

  • What are possible food and drug interactions associated with Hycamtin Injection?

    If Hycamtin injection is given with certain other drugs, the effects of either could be increased, decreased, or altered. It is important to tell your doctor before combining Hycamtin injection with any other medication.

  • What are the possible side effects of Hycamtin Injection?

    Side effects cannot be anticipated. If any develop or change in intensity, tell your doctor as soon as possible. Only your doctor can determine if it is safe for you to continue taking this drug.

    Side effects may include: constipation, cough, diarrhea, fever, hair loss, headache, infections, loss of appetite, low blood cell counts, nausea, rash, stomach pain, tiredness, vomiting, weakness

  • Can I receive Hycamtin Injection if I am pregnant or breastfeeding?

    Hycamtin injection may cause harm to your unborn baby if you receive it during pregnancy. Do not breastfeed while you are receiving Hycamtin injection. Tell your doctor immediately if you are pregnant, plan to become pregnant, or are breastfeeding.

  • What should I do if I miss a dose of Hycamtin Injection?

    Do not miss your follow-up appointments with your doctor.

  • How should I store Hycamtin Injection?

    Your doctor will store this medication for you.