Isosorbide Dinitrate Sublingual Tablets

Generic Name: Isosorbide

  • What is this medication and its most common uses?

    Isosorbide dinitrate sublingual (SL) tablet is a medicine used to relieve sudden chest pain or prevent chest pain associated with coronary artery disease (narrowing of the small blood vessels that supply blood and oxygen to the heart). Isorbide dinitrate is available as a sublingual tablet (dissolved under the tongue).

  • What should I know when beginning and continuing on this medication?

    How does this medication work?

    Isosorbide dinitrate SL works by relaxing the blood vessels in your muscles, including your heart.

    What are the beneficial effects of this medication and when should I begin to have results?

    What: Isosorbide dinitrate SL has been shown to relieve chest pain.

    When: Isosorbide dinitrate SL may start working within a few minutes of taking a dose.

    How do I know it is working?

    You may feel an improvement in your chest pain after you take isosorbide dinitrate SL. This is a good indicator that the medicine is working. Your healthcare provider may ask you questions to assess how well your symptoms are controlled.

  • What are the possible side effects of this medication?

    The following is not a full list of side effects. Side effects cannot be anticipated. If any develop or change in intensity, tell your healthcare provider as soon as possible. Only your healthcare provider can determine if it is safe for you to continue taking this medication.

    More common side effects may include: headache.

    Less common side effects may include:

    Isosorbide dinitrate SL may cause lightheadedness, slow heart rate, or increased chest pain.

    Severe low blood pressure, especially if you also take a medicine called sildenafil.

  • Who should not take this medication?

    Do not take isosorbide dinitrate SL if you are allergic to it or any of its ingredients.

  • What should I tell my healthcare provider before I take the first dose of this medication?

    Tell your healthcare provider about all prescription, over-the-counter, and herbal medications you are taking before beginning treatment with isosorbide dinitrate SL. Also, talk to your healthcare provider about your complete medical history, especially if you have low blood pressure or heart problems (such as heart failure or a recent heart attack).

  • What is the usual dosage?

    The information below is based on the dosage guidelines your healthcare provider uses. Depending on your condition and medical history, your healthcare provider may prescribe a different regimen. Do not change the dosage or stop taking your medication without your healthcare provider's approval.

    Chest Pain Prevention

    Adults: The usual dose is 2.5 to 5 milligrams about 15 minutes before engaging in activities that may cause chest pain, as directed by your healthcare provider.

    Chest Pain Treatment

    Adults: Your healthcare provider will prescribe the appropriate dose for you.

    If you are elderly, your healthcare provider may adjust your dose appropriately.

  • How should I take this medication?

    Take isosorbide dinitrate SL exactly as prescribed by your healthcare provider. Do not change your dose without first talking to your healthcare provider.

    Your daily regimen should include a period of 14 hours without the medicine.

  • What should I avoid while taking this medication?

    Do not change your dose without first talking to your healthcare provider.

  • What are the possible food and drug interactions associated with this medication?

    If isosorbide dinitrate SL is taken with certain other drugs, the effects of either could be increased, decreased, or altered. It is especially important to check with your healthcare provider before combining isosorbide dinitrate SL with alcohol.

  • May I receive this medication if I am pregnant or breastfeeding?

    The effects of isosorbide dinitrate SL during pregnancy and breastfeeding are unknown. Tell your healthcare provider immediately if you are pregnant, plan to become pregnant, or are breastfeeding.

  • What should I do if I miss a dose of this medication?

    Isosorbide dinitrate SL should be taken only as needed.

  • How should I store this medication?

    Store at room temperature. Protect from light and moisture.