Janumet

Generic Name: Sitagliptin

  • What is Janumet?

    Janumet contains two medicines that are used to treat type 2 diabetes (non-insulin-dependent) in addition to diet, exercise, and if needed, weight loss.

  • What is the most important information I should know about Janumet?

    Janumet can cause a rare but serious condition called lactic acidosis. Tell your doctor if you experience any of the following symptoms: feeling very weak, tired, or uncomfortable; unusual muscle pain; unusual sleepiness; unexplained rapid breathing; unusual or unexpected stomach problems (such as nausea or vomiting); low body temperature; feeling dizzy or lightheaded; or suddenly having a slow or uneven heartbeat.

    Janumet can cause a serious allergic reaction, including rash, hives, and swelling of the face, lips, tongue, or throat, which may cause difficulty breathing or swallowing. If you have an allergic reaction, stop taking Janumet and call your doctor right away.

    Janumet may cause a condition known as pancreatitis (inflammation of the pancreas). You may experience severe pain in the stomach all the way to your back that will not go away, and it may happen with or without vomiting. If you experience any of these symptoms, stop taking Janumet and call your doctor immediately.

    Janumet may cause low blood sugar, making you feel lightheaded, dizzy, shaky, and hungry. Call your doctor if this is a continuous problem for you.

  • Who should not take Janumet?

    Do not take Janumet if you are allergic to any of its ingredients. You should also not take Janumet if you have any of the following: type 1 diabetes, kidney disease, a history of pancreatitis, or if you are going to receive an injection of a dye or contrast agent for an x-ray procedure.

  • What should I tell my doctor before I take the first dose of Janumet?

    Tell your doctor about all prescription, over-the-counter, and herbal medications you are taking before beginning treatment with Janumet. Also, talk to your doctor about your complete medical history, especially if you have a history of liver, kidney, or heart problems. Tell your doctor if you drink alcohol frequently or if you are a binge drinker. Also tell your doctor if you are pregnant, plan to become pregnant, or are breastfeeding.

  • What is the usual dosage?

    The information below is based on the dosage guidelines your doctor uses. Depending on your condition and medical history, your doctor may prescribe a different regimen. Do not change the dosage or stop taking your medication without your doctor's approval.

    Adults: Janumet is usually taken twice a day with meals. Your doctor will prescribe the appropriate dose for you.

  • How should I take Janumet?

    Take Janumet exactly as directed by your doctor. You should take it with food to lower the chance of getting an upset stomach.

  • What should I avoid while taking Janumet?

    Avoid drinking excessive amounts of alcohol while taking Janumet.

  • What are possible food and drug interactions associated with Janumet?

    If Janumet is taken with certain other drugs, the effects of either could be increased, decreased, or altered. It is especially important to check with your doctor before combining it with the following: blood pressure drugs known as calcium channel blockers, cimetidine, corticosteroids, digoxin, diuretics (water pills), estrogen, furosemide, isoniazid, nicotinic acid, nifedipine, birth control pills, phenytoin, and thyroid medications.

  • What are the possible side effects of Janumet?

    Side effects cannot be anticipated. If any develop or change in intensity, tell your doctor as soon as possible. Only your doctor can determine if it is safe for you to continue taking this drug.

    Side effects may include: stuffy or runny nose, sore throat, common cold, diarrhea, nausea and vomiting, gas, stomach discomfort, indigestion, weakness, headache

    Symptoms of low blood sugar: blurred vision, cold sweats, coma, dizziness, fast heartbeat, fatigue, headache, hunger, lightheadedness, nausea, nervousness, pale skin, shallow breathing

  • Can I receive Janumet if I am pregnant or breastfeeding?

    The effects of Janumet during pregnancy and breastfeeding are unknown. Tell your doctor immediately if you are pregnant, plan to become pregnant, or are breastfeeding.

  • What should I do if I miss a dose of Janumet?

    If you miss a dose, take it with food as soon as you remember. If it is almost time for your next dose, skip the one you missed and go back to your regular schedule. Do not take two doses at once.

  • How should I store Janumet?

    Store at room temperature in a tightly closed container.

Meet the Pharmacists

I'm Shereen A. Gharbia, PharmD. Welcome to PDR Health!

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