What is Jevtana?Jevtana is a medicine used to treat prostate cancer that has worsened after treatment with other anticancer medicines, including docetaxel. Jevtana is administered intravenously (through a vein in your arm).
What is the most important information I should know about Jevtana?Jevtana can cause a decrease in neutrophil counts in your blood (a type of blood cell that fights infections). This may increase your risk of developing an infection. Tell your doctor if you experience a fever, cough, burning on urination, muscle aches, diarrhea, or other signs of an infection. Jevtana can also cause low platelet counts (type of blood cells that form clots to help stop bleeding) or low red blood cell counts. Your doctor will monitor your blood cell counts before you start Jevtana and regularly during your treatment.
Serious allergic reactions, that may result in death if not immediately treated, can occur while you are receiving Jevtana. Tell your doctor immediately if you experience rash or itching, skin redness, feeling dizzy or faint, breathing problems, chest or throat tightness, or swelling of your face. Also, tell your doctor if you have experienced this reaction before while receiving Jevtana.
Nausea, vomiting, and severe diarrhea can happen when you receive Jevtana. This can lead to too much body fluid loss (dehydration) or electrolyte loss (chemicals that are important for the cells in your body to function, such as sodium and potassium). Tell your doctor if you experience these symptoms.
Jevtana can cause kidney failure. Your doctor will monitor your kidney function while you are receiving this medication. Tell your doctor if you develop swelling of your face or body or a decrease in urination. In addition, if you have liver impairment, exposure and toxicity of Jevtana can increase. Tell your doctor if you have liver problems.
Jevtana can cause harm to your unborn baby if you receive it during pregnancy. Tell your doctor immediately if you are pregnant or plan to become pregnant.
Who should not take Jevtana?Your doctor will not administer Jevtana if you are allergic to it, any of its ingredients, or other medicines that contain polysorbate 80. Also, your doctor will not administer Jevtana if you have a low neutrophil count.
What should I tell my doctor before I take the first dose of Jevtana?Tell your doctor about all prescription, over-the-counter, and herbal medications you are taking before beginning treatment with Jevtana. Also, talk to your doctor about your complete medical history, especially if you have liver or kidney problems, or are pregnant, plan to become pregnant, or are breastfeeding.
What is the usual dosage?The information below is based on the dosage guidelines your doctor uses. Depending on your condition and medical history, your doctor may prescribe a different regimen. Do not change the dosage or stop taking your medication without your doctor's approval.
Adults: Your doctor will prescribe the appropriate dose for you based on your weight.
If you experience severely low neutrophil counts or severe diarrhea, your doctor will adjust the dose appropriately.
How should I take Jevtana?Your doctor will administer Jevtana intravenously through a needle placed in a vein. It takes about 1 hour to give you the full dose of Jevtana. Your doctor will tell you how often you should receive Jevtana. Your doctor will also prescribe another medicine called prednisone for you to take during treatment with Jevtana.
What should I avoid while taking Jevtana?Do not miss your scheduled appointment to receive Jevtana.
What are possible food and drug interactions associated with Jevtana?If Jevtana is used with certain other drugs, the effects of either could be increased, decreased, or altered. It is especially important to tell your doctor if you are taking any of the following prior to treatment with Jevtana: carbamazepine, certain antibiotics (such as clarithromycin or telithromycin), certain antifungals (such as itraconazole, ketoconazole, or voriconazole), HIV infection (AIDS) medications (such as atazanavir, indinavir, nelfinavir, ritonavir, or saquinavir), nefazodone, phenobarbital, phenytoin, rifabutin, rifampin, rifapentin, or St. John's wort.
What are the possible side effects of Jevtana?Side effects cannot be anticipated. If any develop or change in intensity, tell your doctor as soon as possible. Only your doctor can determine if it is safe for you to continue taking this drug.
Side effects may include: abdominal pain, allergic reactions, back pain, blood in your urine, burning in your hands or feet, change in your sense of taste, constipation, cough, decreased appetite, decreased blood cell counts, diarrhea, fever, hair loss, joint pain, nausea, numbness or tingling in your hands or feet, shortness of breath, tiredness, vomiting, weakness
Can I receive Jevtana if I am pregnant or breastfeeding?Jevtana can cause harm to your unborn baby if you receive it during pregnancy. The effects of Jevtana during breastfeeding are unknown. Tell your doctor immediately if you are pregnant, plan to become pregnant, or are breastfeeding.
What should I do if I miss a dose of Jevtana?Contact your doctor if you miss your scheduled appointment to receive Jevtana.
How should I store Jevtana?Your doctor will store this medication for you.