What is Juvisync?Juvisync is a medicine used in addition to diet and exercise to lower blood sugar and cholesterol in adults with type 2 diabetes. Juvisync contains two medicines, sitagliptin and simvastatin. It lowers triglycerides and "bad" (low density lipoprotein [LDL]) cholesterol, and it raises the "good" (high density lipoprotein [HDL]) cholesterol. Juvisync can reduce your risk of death from heart problems, heart attack, stroke, or the need for certain blood vessel procedures.
What is the most important information I should know about Juvisync?Juvisync can cause a condition known as pancreatitis (inflammation of the pancreas). You can experience severe pain in the stomach all the way to your back that will not go away, and it can happen with or without vomiting. If you experience any of these symptoms, stop taking Juvisync and contact your doctor immediately. Your risk of having these symptoms can be higher if you already have a history of pancreatitis, stones in your gallbladder, alcoholism, high blood triglyceride levels, or kidney problems.
The amount of diabetes medication you need can change if you undergo any kind of stress (such as a fever), trauma (such as a car accident), infection, or surgery. Tell your doctor immediately if you are under any kind of stress.
Make sure to stay on your diet and exercise program, and check your blood sugar regularly.
Who should not take Juvisync?Do not take Juvisync if you are allergic to it or any of its ingredients.
Do not take Juvisync if you are taking certain antibiotics (such as erythromycin or clarithromycin); certain medications for fungal infections (such as itraconazole, ketoconazole, or posaconazole); cyclosporine; danazol; gemfibrozil; HIV medications in a class called protease inhibitors (such as indinavir, ritonavir, or atazanavir); or nefazodone.
Do not take Juvisync if you have active liver disease or liver problems, type 1 diabetes, if you are pregnant, plan to become pregnant, or are breastfeeding.
Do not take Juvisync if you have type 1 diabetes.
What should I tell my doctor before I take the first dose of Juvisync?Tell your doctor about all prescription, over-the-counter, and herbal medications you are taking before beginning treatment with Juvisync. Also, talk to your doctor about your complete medical history, especially if you have pancreatitis, kidney or liver problems, stones in your gallbladder, high blood triglycerides levels, or alcoholism. Also, tell your doctor if you are pregnant, plan to become pregnant, or are breastfeeding.
What is the usual dosage?The information below is based on the dosage guidelines your doctor uses. Depending on your condition and medical history, your doctor may prescribe a different regimen. Do not change the dosage or stop taking your medication without your doctor's approval.
Adults: The recommended dose is 1 tablet once a day in the evening. Your doctor will prescribe the appropriate dose for you based on your current cholesterol medication.
How should I take Juvisync?Take Juvisync as prescribed by your doctor. You can take Juvisync once a day in the evening, with or without food. Do not break, cut, crush, dissolve, or chew Juvisync tablets. Swallow the tablets whole. It is important for you to follow any dietary, exercise, and blood sugar monitoring instructions from your doctor while you are taking this medication.
What should I avoid while taking Juvisync?Do not drink large amounts of alcohol or grapefruit juice while you are taking Juvisync.
What are possible food and drug interactions associated with Juvisync?If Juvisync is taken with certain other drugs, the effects of either could be increased, decreased, or altered. Juvisync may interact with numerous medications. Therefore, it is very important that you tell your doctor about any other medications you are taking.
What are the possible side effects of Juvisync?Side effects cannot be anticipated. If any develop or change in intensity, tell your doctor as soon as possible. Only your doctor can determine if it is safe for you to continue taking this drug.
Side effects may include: constipation, depression, erectile dysfunction, headache, joint pain, muscle breakdown, muscle pain, muscle weakness, nausea, pancreatitis, poor memory, sore throat, stomach pain, stuffy or runny nose, swelling of the hands or legs, tingling sensation, trouble sleeping, upper respiratory (lung) infection
Can I receive Juvisync if I am pregnant or breastfeeding?Do not take Juvisync if you are pregnant or breastfeeding. It can cause harm to your baby. Tell your doctor immediately if you are pregnant, plan to become pregnant, or are breastfeeding.
What should I do if I miss a dose of Juvisync?If you miss a dose of Juvisync, take it as soon as you remember. However, if it is almost time for your next dose, skip the one you missed and return to your regular dosing schedule. Do not take two doses at once.
How should I store Juvisync?Store at room temperature.