Ketoprofen Extended-Release

Generic Name: Ketoprofen

  • What is Ketoprofen Extended-Release?

    Ketoprofen extended-release is a nonsteroidal anti-inflammatory drug (NSAID) that is used to treat signs and symptoms of rheumatoid arthritis or osteoarthritis.

  • What is the most important information I should know about Ketoprofen Extended-Release?

    Ketoprofen extended-release can cause serious problems (such as heart attack or stroke). Your risk can increase when this medication is used for long periods of time and in people who have heart disease. Tell your doctor if you experience chest pain, shortness of breath, weakness, or slurred speech. Also, Ketoprofen extended-release can cause high blood pressure or worsening of existing high blood pressure, and heart failure which can lead to weight gain or edema (swelling).

    Ketoprofen extended-release can cause discomfort, ulcers, or bleeding in your stomach and intestines. Your risk can increase with long-term use, smoking, drinking alcohol, older age, or with certain medications. Tell your doctor immediately if you experience abdominal pain or if you have bloody vomit or stools.

    Ketoprofen extended-release can cause allergic reactions resembling anaphylaxis (a serious and rapid allergic reaction that may result in death if not immediately treated). Stop taking ketoprofen extended-release and tell your doctor immediately if you experience difficulty breathing or swelling of your face, mouth, or throat.

    Ketoprofen extended-release can cause liver injury. Tell your doctor if you experience nausea, tiredness, weakness, itchiness, yellowing of your skin or whites of your eyes, right upper abdominal tenderness, or "flu-like" symptoms.

    Tell your doctor immediately if you experience serious skin reactions which can be characterized by a severe rash, fever, or itchiness.

  • Who should not take Ketoprofen Extended-Release?

    Do not take ketoprofen extended-release for sudden-onset pain.

    Do not take ketoprofen extended-release if you are allergic to it, any of its ingredients, if you experienced asthma, difficulty breathing, rash, or allergic-type reactions after taking aspirin or other NSAIDs.

    Do not take ketoprofen extended-release right before or after a heart surgery called coronary artery bypass graft (CABG).

  • What should I tell my doctor before I take the first dose of Ketoprofen Extended-Release?

    Tell your doctor about all prescription, over-the-counter, and herbal medications you are taking before beginning treatment with ketoprofen extended-release. Also, talk to your doctor about your complete medical history, especially if you have heart disease, stomach problems, kidney or liver impairment, high blood pressure, asthma, or are pregnant, plan to become pregnant, or are breastfeeding.

  • What is the usual dosage?

    The information below is based on the dosage guidelines your doctor uses. Depending on your condition and medical history, your doctor may prescribe a different regimen. Do not change the dosage or stop taking your medication without your doctor's approval.

    Adults ≥18 years: The recommended starting dose is 200 milligrams (mg) once a day.

    If you have severe kidney or liver impairment, your doctor will adjust your dose appropriately.

  • How should I take Ketoprofen Extended-Release?

    Take ketoprofen extended-release exactly as prescribed by your doctor. If stomach discomfort occurs, you can take ketoprofen extended-release with antacids, food, or milk.

  • What should I avoid while taking Ketoprofen Extended-Release?

    Do not take aspirin or other NSAIDs in combination with ketoprofen extended-release.

  • What are possible food and drug interactions associated with Ketoprofen Extended-Release?

    If ketoprofen extended-release is taken with certain other drugs, the effects of either could be increased, decreased, or altered. It is especially important to check with your doctor before combining ketoprofen extended-release with the following: aspirin, blood pressure/heart medications known as angiotensin-converting enzyme (ACE) inhibitors (such as lisinopril or ramipril), blood thinners (such as warfarin), diuretics (water pills) (such as hydrochlorothiazide), lithium, methotrexate, or probenecid.

  • What are the possible side effects of Ketoprofen Extended-Release?

    Side effects cannot be anticipated. If any develop or change in intensity, tell your doctor as soon as possible. Only your doctor can determine if it is safe for you to continue taking this drug.

    Side effects may include: abdominal or stomach pain, constipation, diarrhea, difficulty falling asleep, dizziness, gas, headache, heartburn, indigestion, nausea, nervousness, vomiting

  • Can I receive Ketoprofen Extended-Release if I am pregnant or breastfeeding?

    Do not take ketoprofen extended-release if you are in the late stage of your pregnancy. The effects of ketoprofen extended-release during early pregnancy and breastfeeding are unknown. Tell your doctor immediately if you are pregnant, plan to become pregnant, or are breastfeeding.

  • What should I do if I miss a dose of Ketoprofen Extended-Release?

    If you miss a dose of ketoprofen extended-release, take it as soon as you remember. However, if it is almost time for your next dose, skip the one you missed and return to your regular dosing schedule. Do not take two doses at once.

  • How should I store Ketoprofen Extended-Release?

    Store at room temperature. Protect from light and excessive heat and humidity.