Ketorolac tromethamine
Generic Name: Ketorolac
What is Ketorolac tromethamine?
Ketorolac is a nonsteroidal anti-inflammatory drug (NSAID) used to relieve moderately severe, acute pain. It is prescribed for a limited amount of time (no more than 5 days for adults and as a single dose for children), not for long-term therapy.What is the most important information I should know about Ketorolac tromethamine?
Ketorolac and other NSAIDs may increase the risk of developing serious life-threatening heart or circulation problems, such as heart attack and stroke, especially with long-term use, and may result in hospitalization and even death. These events may occur without warning signs. Tell your doctor immediately if you experience chest pain, shortness of breath, or weakness.Ketorolac and other NSAIDs can cause stomach discomfort. Rarely, serious ulcers or internal bleeding can occur without warning and result in hospitalization or even death. Tell your doctor immediately if you experience stomach pain, indigestion, or bloody vomit or stools. The risk of getting an ulcer or bleeding is greater if you take a corticosteroids or blood thinners, use NSAIDs for an extended period of time, or if you smoke or drink alcohol, are older, or are in poor health.
Never take Ketorolac for more than 5 days.
This medication should be used with caution if you have kidney or liver disease. It may cause liver inflammation or kidney problems in some people.
Never combine this medication with aspirin, probenecid or other NSAIDs. Make sure your doctor is aware of any drug reactions you have experienced.
Who should not take Ketorolac tromethamine?
Do not take Ketorolac if you have had an allergic reaction to it or if you have ever had an allergic reaction to aspirin or other NSAIDs. Symptoms include nasal polyps (tumors), swelling of the face, limbs, and throat, hives, wheezing, and light-headedness.Do not take Ketorolac for the treatment of pain associated with coronary artery bypass graft (CABG) surgery or for use before major surgery.
Do not take Ketorolac if you have ever had a peptic ulcer or stomach or intestinal bleeding. Avoid it if you have severe kidney disease or bleeding problems.
What should I tell my doctor before I take the first dose of Ketorolac tromethamine?
Tell your doctor about all prescription, over-the-counter, and herbal medications you are taking before beginning treatment with Ketorolac. Also talk to your doctor about your complete medical history, especially if you have ever had kidney or liver problems, ulcers, intestinal bleeding, heart disease, high blood pressure, or if you are taking blood thinners, have a blood clotting problem, asthma, or if you smoke or drink alcohol. Also tell your doctor if you are pregnant, plan to become pregnant, or are breastfeeding.What is the usual dosage?
The information below is based on the dosage guidelines your doctor uses. Depending on your condition and medical history, your doctor may prescribe a different regimen. Do not change the dosage or stop taking your medication without your doctor's approval.Adults and Children ≥17 Years: Your doctor may give you Ketorolac intravenously (through a vein) or intramuscularly (an injection into the muscle) to start, then have you switch to the tablet form. Most patients take two tablets for the first dose (20 milligrams) and then one tablet (10 milligrams) every 4-6 hours. You should not take more than 40 mg per day. Never take Ketorolac for more than 5 days in all.
Adults ≥65, ≤110 pounds, or with kidney problems: 10 mg once followed by 10 mg every 4-6 hours as needed. Do not take more than 40 mg per day.
Children <16 Years: For children under 16, the doctor may prescribe a single dose of Ketorolac, by intravenous or intramuscular injection, after an operation.
Ketorolac is not recommended for children under 2 years.
How should I take Ketorolac tromethamine?
Take Ketorolac exactly as prescribed. Take it with a full glass of water. Ketorolac works fastest when taken on an empty stomach, but can be taken with an antacid if it causes an upset stomach.What should I avoid while taking Ketorolac tromethamine?
Avoid lying down for about 20 minutes after taking Ketorolac. This will help to prevent irritation of your upper digestive tract.What are possible food and drug interactions associated with Ketorolac tromethamine?
If Ketorolac is taken with certain other drugs, the effects of either could be increased, decreased, or altered. It is especially important to check with your doctor before combining Ketorolac with the following: ACE inhibitors, antidepressants, antianxiety medications, antiepileptic drugs, aspirin and other NSAIDs, blood thinners, lithium, methotrexate, probenecid, alprazolam, and diuretics.What are the possible side effects of Ketorolac tromethamine?
Side effects cannot be anticipated. If any develop or change in intensity, tell your doctor as soon as possible. Only your doctor can determine if it is safe for you to continue taking this drug.Side effects may include: diarrhea, dizziness, drowsiness, headache, indigestion, nausea, stomach and intestinal pain, swelling due to fluid retention
Can I receive Ketorolac tromethamine if I am pregnant or breastfeeding?
Ketorolac should not be taken late in pregnancy; during this period, it can harm the developing baby. If you are pregnant or plan to become pregnant, inform your doctor immediately. Ketorolac appears in breast milk and could affect a nursing infant. This medication should not be used while you are breastfeeding.What should I do if I miss a dose of Ketorolac tromethamine?
If you take Ketorolac on a regular schedule, take it as soon as you remember. If it is almost time for your next dose, skip the one you missed and go back to your regular schedule. Never take two doses at the same time.How should I store Ketorolac tromethamine?
Store at room temperature, away from light.
I'm Beth Isaac, PharmD. Welcome to PDR Health!
