Generic Name: Sodium Polystyrene

  • What is Kionex?

    Kionex is used to treat high potassium levels in the blood (also called hyperkalemia). It can be given orally or as an enema.

  • What is the most important information I should know about Kionex?

    Serious potassium deficiency can occur from therapy with Kionex. In extreme cases of potassium deficiency, severe muscle weakness can occur that may lead to paralysis.

  • Who should not take Kionex?

    Do not take Kionex if you have low potassium levels, obstructive bowel disease, or a history of allergic reactions to polystyrene sulfonate resins. Kionex should not be given to newborns with a slow digestive system. Kionex should not be administered to newborns by mouth.

  • What should I tell my doctor before I take the first dose of Kionex?

    Tell your doctor about all prescription, over-the-counter, and herbal medications you are taking before beginning treatment with Kionex. Also talk to your doctor about your complete medical history, especially if you have congestive heart failure, severe high blood pressure, severe edema (swelling), or severe constipation.

  • What is the usual dosage?

    The information below is based on the dosage guidelines your doctor uses. Depending on your condition and medical history, your doctor may prescribe a different regimen. Do not change the dosage or stop taking your medication without your doctor's approval.

    Adults: The recommended dosage is 15-60 grams (g) daily when taken by mouth. When given as an enema, the recommended dosage is 30-50 g every 6 hours.

    Children: The recommended dosage will be calculated by your doctor.

  • How should I take Kionex?

    Take Kionex as directed by your doctor.

  • What should I avoid while taking Kionex?

    Do not use any laxatives, antacids, or sorbitol while receiving Kionex.

  • What are possible food and drug interactions associated with Kionex?

    If Kionex is used with certain other drugs, the effects of either could be increased, decreased, or altered. It is especially important to check with your doctor before combining Kionex with the following: antacids, digoxin, laxatives, lithium, sorbitol, and thyroxine.

  • What are the possible side effects of Kionex?

    Side effects cannot be anticipated. If any develop or change in intensity, tell your doctor as soon as possible. Only your doctor can determine if it is safe for you to continue taking this drug.

    Side effects may include: stomach upset, electrolyte imbalance, diarrhea, alkalosis (a condition that disrupts the body's natural acid/base balance), abnormal heart rate, loss of appetite, constipation, low potassium levels, intestinal obstruction, nausea, vomiting

  • Can I receive Kionex if I am pregnant or breastfeeding?

    The effects of Kionex during pregnancy and breastfeeding are unknown. Tell your doctor immediately if you are pregnant, plan to become pregnant, or are breastfeeding.

  • What should I do if I miss a dose of Kionex?

    Ask your doctor for advice.

  • How should I store Kionex?

    Your healthcare provider will store Kionex.

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