Lantus
Generic Name: Insulin Glargine, Human
What is Lantus?
Lantus is a long-acting form of insulin that helps lower levels of sugar in the blood. It is used to manage blood sugar levels in adults and children with type 1 diabetes and in adults with type 2 diabetes.What is the most important information I should know about Lantus?
Do not make any changes with your insulin dose unless you have talked to your doctor. Your insulin needs may change because of illness, stress, other medicines, or changes in diet or activity level. Talk to your doctor about adjusting your insulin dose and before engaging in any new activity (such as a new exercise regimen or diet plan). Illness, especially with nausea and vomiting, may cause your insulin requirements to change. Even if you are not eating, you still require insulin. You and your doctor should establish a sick day plan to use in case of illness. When you are sick, test your blood/urine frequently and call your doctor as instructed.Lantus is only intended to be injected under the skin. Do not administer Lantus into a vein or through an insulin pump. Also, do not dilute or mix Lantus with any other insulin or solutions.
Lantus can cause you to experience low blood sugar. Therefore, it is important to take Lantus exactly as prescribed by your doctor. It is a good idea to carry a reliable source of glucose (such as glucose tablets or gel) to treat low blood sugar. If this is not available, eat or drink a quick source of sugar such as table sugar, honey, candy, orange juice, or non-diet soda. This will raise your blood sugar level quickly. Contact your doctor immediately if you feel any symptoms of low blood sugar such as dizziness, lightheadedness, tingling in your extremities, palpitations, sweating, or tremor.
Who should not take Lantus?
Do not take Lantus if you are allergic to any of its ingredients.What should I tell my doctor before I take the first dose of Lantus?
Tell your doctor about all prescription, over-the-counter, and herbal medications you are taking before beginning treatment with Lantus. Also, talk to your doctor about your complete medical history, especially if you have liver or kidney problems, if you are pregnant, plan to become pregnant, or are breastfeeding.What is the usual dosage?
The information below is based on the dosage guidelines your doctor uses. Depending on your condition and medical history, your doctor may prescribe a different regimen. Do not change the dosage or stop taking your medication without your doctor's approval.Type 1 Diabetes
Adults and children 6-17 years: Your doctor will prescribe the appropriate dose for you.
Type 2 Diabetes
Adults: The initial starting dose of Lantus should be 10 units (or 0.2 units per 2.2 pounds of body weight) given as a subcutaneous (under the skin) injection once daily. Your doctor may then individualize your dose based on your blood sugar measurements.
How should I take Lantus?
You may take Lantus anytime during the day, but you must take it at the same time everyday.Only use Lantus that is clear and colorless. If your Lantus is cloudy or colored, return it to your pharmacy for a replacement. Do not dilute or mix Lantus with any other insulin or solutions.
Inject Lantus under your skin in your upper arm, abdomen, or thigh. Never inject it into a vein or muscle. Rotate injection sites within the same body area.
Use the proper injection technique taught to you by your doctor. Refer to the package insert that accompanies Lantus for detailed instructions.
Do not make any changes with your insulin unless you have talked to your doctor.
What should I avoid while taking Lantus?
You should avoid drinking alcohol while taking Lantus. Alcohol can affect the way Lantus works and can alter your blood sugar levels.Do not freeze or overheat Lantus; it must be kept refrigerated or at room temperature once opened.
Do not inject Lantus in the same place twice; rotate injection sites. Do not mix this insulin with any other insulin.
What are possible food and drug interactions associated with Lantus?
If Lantus is taken with certain other drugs, the effects of either could be increased, decreased, or altered. It is especially important to check with your doctor before combining Lantus with the following: alcohol, albuterol, oral antidiabetic drugs, antipsychotics, blood pressure medications including ACE inhibitors and beta-blockers, certain cholesterol medications, clonidine, corticosteroids, danazol, disopyramide, diuretics (water pills), epinephrine, estrogens, fluoxetine, guanethidine, isoniazid, antidepressant medications in a class known as MAO inhibitors, niacin, octreotide, pentamide, some birth control pills, propoxyphene, anti-HIV drugs in a class called protease inhibitors, reserpine, salicylates, somatropin, sulfonamide antibiotics, terbutaline, and thyroid hormones.What are the possible side effects of Lantus?
Side effects cannot be anticipated. If any develop or change in intensity, tell your doctor as soon as possible. Only your doctor can determine if it is safe for you to continue taking this drug.Side effects may include: low blood sugar, injection-site reactions, allergic reactions
Signs of low blood sugar: sweating, dizziness, shakiness, hunger, fast heartbeat, blurred vision, headache, trouble concentrating. If these symptoms occur, tell your doctor right away.
Signs of high blood sugar: increased thirst, frequent urination, loss of appetite, fruity breath smell. If these symptoms occur, tell your doctor right away.
Can I receive Lantus if I am pregnant or breastfeeding?
The effects of Lantus during pregnancy and breastfeeding are unknown. Tell your doctor immediately if you are pregnant, plan to become pregnant, or are breastfeeding.What should I do if I miss a dose of Lantus?
It is very important to follow your insulin regimen exactly. Do not miss any doses. Ask your doctor for specific instructions to follow in case you ever miss a dose of insulin.How should I store Lantus?
Unopened Lantus: Store in the refrigerator (not the freezer). Do not use after the expiration date printed on the label.Opened Lantus: Store in the refrigerator or at room temperature for 28 days. Opened Lantus SoloStar delivery devices should not be refrigerated, but should be kept at room temperature away from direct heat and light for 28 days.
I'm Kristen Dore, PharmD. Welcome to PDR Health!
