Generic Name: Fenofibrate

  • What is Lofibra?

    Lofibra is a cholesterol-lowering medicine used, in addition to an appropriate diet, to treat adults with high cholesterol. Lofibra reduces bad cholesterol (LDL-C), total cholesterol, triglycerides, and apolipoprotein B; and increases good cholesterol (HDL-C). Lofibra is used when diet and exercise alone have not lowered bad cholesterol and triglycerides. Lofibra is available in capsules and tablets.

  • What is the most important information I should know about Lofibra?

    Tell your doctor if you are taking any other medications while you are taking Lofibra. Lofibra may have an effect on drugs that help prevent blood clotting (such as the blood thinner warfarin). If you are taking Lofibra with a blood thinner, your doctor will monitor your blood-clotting tests. Also, tell your doctor about any cholesterol-lowering medicines you may be taking as he or she will need to determine if the combination of Lofibra and one of those medications is right for you.

    Lofibra can cause liver problems. Your doctor will monitor your liver function.

    Lofibra can increase your risk of developing gallstones. Call your doctor immediately if you experience abdominal pain, nausea, or vomiting. These may be signs of inflammation of your gallbladder or pancreas. Your doctor will also do studies to check for gallstones.

    Lofibra can cause serious muscle conditions that may lead to kidney damage. Your risk can increase if you are also taking other cholesterol-lowering medicines known as statins (atorvastatin, fluvastatin, lovastatin, or pravastatin). Tell your doctor immediately if you experience unexplained muscle pain, weakness, or tenderness, especially if you also have a fever or general body discomfort.

    Lofibra can cause pancreatitis (inflammation of the pancreas), severe allergic reactions, and clotting problems.

  • Who should not take Lofibra?

    Do not take Lofibra if you are allergic to it or any of its ingredients; or if you have liver, gallbladder, or severe kidney problems.

  • What should I tell my doctor before I take the first dose of Lofibra?

    Tell your doctor about all prescription, over-the-counter, and herbal medications you are taking before beginning treatment with Lofibra. Also, talk to your doctor about your complete medical history, especially if you have liver, kidney, or gallbladder problems; hypothyroidism (an underactive thyroid gland); diabetes; blood disorders; muscle pain or disease; if you consume large amounts of alcohol; or are pregnant, plan to become pregnant, or are breastfeeding.

  • What is the usual dosage?

    The information below is based on the dosage guidelines your doctor uses. Depending on your condition and medical history, your doctor may prescribe a different regimen. Do not change the dosage or stop taking your medication without your doctor's approval.

    Adults: Your doctor will prescribe the appropriate dose for you based on your condition.

    If you have kidney problems, your doctor will adjust your dose appropriately.

  • How should I take Lofibra?

    Take Lofibra exactly as prescribed by your doctor.

    If you are taking Lofibra with another type of cholesterol-lowering medicine called a bile acid sequestrant (such as colestipol and cholestyramine), take Lofibra at least 1 hour before or 4-6 hours after you take the other medicine.

  • What should I avoid while taking Lofibra?

    Do not drink alcohol while you are taking Lofibra. Alcohol can raise your triglyceride levels, and may also damage your liver while you are taking Lofibra.

  • What are possible food and drug interactions associated with Lofibra?

    If Lofibra is taken with certain other drugs, the effects of either could be increased, decreased, or altered. It is especially important to check with your doctor before combining Lofibra with the following: bile acid sequestrants, blood thinners, cyclosporine, or statins.

  • What are the possible side effects of Lofibra?

    Side effects cannot be anticipated. If any develop or change in intensity, tell your doctor as soon as possible. Only your doctor can determine if it is safe for you to continue taking this drug.

    Side effects may include: abdominal pain, back pain, headache, liver damage, respiratory problems

  • Can I receive Lofibra if I am pregnant or breastfeeding?

    The effects of Lofibra during pregnancy and breastfeeding are unknown. Tell your doctor immediately if you are pregnant, plan to become pregnant, or are breastfeeding.

  • What should I do if I miss a dose of Lofibra?

    If you miss a dose of Lofibra, take it as soon as you remember. However, if it is almost time for your next dose, skip the one you missed and return to your regular dosing schedule. Do not take two doses at once.

  • How should I store Lofibra?

    Store at room temperature. Protect from moisture.