Generic Name: Metoprolol

  • What is this medication and its most common uses?

    Lopressor is a medicine known as a beta-blocker, which is used alone or in combination with other medicines to treat high blood pressure. Lopressor is also used to treat chest pain and to lower the risk of death in people who have had a heart attack.

  • What should I know when beginning and continuing on this medication?

    How does this medication work?

    Lopressor works by decreasing your heart rate, and relaxing and widening your blood vessels, allowing your blood to flow through with less resistance. This helps to lower your blood pressure.

    What are the beneficial effects of this medication and when should I begin to have results?


    High Blood Pressure: By lowering your blood pressure, Lopressor may lower your risk of a stroke or a heart attack.

    Chest Pain: Lopressor may reduce the number of chest pain attacks and improve exercise tolerance.

    Heart Attack: Lopressor may reduce the chance of death after a heart attack.

    When: Lopressor may start lowering your blood pressure within 1 week. Though you may not feel an improvement or change in the way you feel, it is very important to keep taking your medicine as prescribed to keep your condition under control.

    How do I know it is working?

    Check your blood pressure regularly. Your healthcare provider will also check your blood pressure at every visit. Following an appropriate diet and exercise plan will also affect your blood pressure results.

  • What are the possible side effects of this medication?

    The following is not a full list of side effects. Side effects cannot be anticipated. If any develop or change in intensity, tell your healthcare provider as soon as possible. Only your healthcare provider can determine if it is safe for you to continue taking this medication.

    Do not stop taking Lopressor without first talking to your healthcare provider. Stopping Lopressor suddenly may cause severe chest pain, a heart attack, or a life-threatening irregular heartbeat.

    More common side effects may include: slow heartbeat.

    Less common side effects may include:

    Breathing problems or worsened heart failure with symptoms such as weight gain, increased shortness of breath, or a slow heartbeat.

    Lopressor may hide symptoms of low blood sugar levels if you have diabetes.

  • Who should not take this medication?

    Do not take Lopressor if you are allergic to it or any of its ingredients.

    Do not take Lopressor if you have certain heart problems (such as heart failure, a slow heartbeat, or your heart skips a beat).

    Do not take Lopressor if you have problems with blood flow in your feet and legs.

  • What should I tell my healthcare provider before I take the first dose of this medication?

    Tell your healthcare provider about all prescription, over-the-counter, and herbal medications you are taking before beginning treatment with Lopressor. Also, talk to your healthcare provider about your complete medical history, especially if you have lung problems (such as bronchitis or emphysema); pheochromocytoma (tumor of the adrenal gland); diabetes; liver or thyroid problems; or if you are scheduled for surgery.

    Tell your healthcare provider if you have a history of severe allergic reactions to any allergens, because Lopressor may decrease the effectiveness of epinephrine, a medicine used to treat such reactions.

  • What is the usual dosage?

    The information below is based on the dosage guidelines your healthcare provider uses. Depending on your condition and medical history, your healthcare provider may prescribe a different regimen. Do not change the dosage or stop taking your medication without your healthcare provider's approval.

    High Blood Pressure

    Adults: The usual starting dose is 100 milligrams (mg) a day, taken once a day or in divided doses. Your healthcare provider may increase your dose as needed until the desired effect is achieved.

    Chest Pain

    Adults: The usual starting dose is 50 mg twice a day. Your healthcare provider may increase your dose as needed until the desired effect is achieved.

    Heart Attack

    Adults: Your healthcare provider will prescribe the appropriate dose for you based on your condition.

    If you have liver impairment, your healthcare provider may adjust your dose appropriately.

    It is important that you do not stop taking this medication abruptly. If you need to change or stop taking this medication, it is important that you only do this with the guidance of your healthcare provider.

  • How should I take this medication?

    Take Lopressor exactly as prescribed by your healthcare provider. Do not change your dose or stop taking Lopressor without first talking to your healthcare provider.

    Take Lopressor with or right after meals.

  • What should I avoid while taking this medication?

    Do not drive a car, operate machinery, or engage in other tasks requiring alertness until you know how Lopressor affects you.

  • What are the possible food and drug interactions associated with this medication?

    If Lopressor is taken with certain other drugs, the effects of either could be increased, decreased, or altered. It is especially important to check with your healthcare provider before combining Lopressor with the following: betanidine, blood pressure/heart medications known as calcium channel blockers (such as diltiazem or verapamil), bupropion, certain migraine medicines (such as ergotamine), chlorpromazine, clomipramine, clonidine, desipramine, digoxin, diphenhydramine, dipyridamole, fluoxetine, fluphenazine, fluvoxamine, guanethidine, haloperidol, hydralazine, hydroxychloroquine, methyldopa, paroxetine, propafenone, quinidine, reserpine, ritonavir, sertraline, terbinafine, or thioridazine.

  • May I receive this medication if I am pregnant or breastfeeding?

    The effects of Lopressor during pregnancy are unknown. Lopressor can be found in your breast milk if you take it while breastfeeding. Tell your healthcare provider immediately if you are pregnant, plan to become pregnant, or are breastfeeding.

  • What should I do if I miss a dose of this medication?

    If you miss a dose of Lopressor, take it as soon as you remember. However, if it is almost time for your next dose, skip the one you missed and return to your regular dosing schedule. Do not take two doses at once.

  • How should I store this medication?

    Store at room temperature. Protect from moisture and heat.

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