Lupron Depot (for use in men)

Generic Name: Leuprolide acetate

  • What is Lupron Depot?

    This form of Lupron Depot is used to help treat advanced prostate cancer in men. It is not a cure. Lupron Depot works by lowering the amount of testosterone produced by the body, which may help to relieve symptoms such as pain and difficulty urinating. Lupron Depot can slow down or stop the growth of prostate cancer that has spread and may also reduce the risk of complications.
  • What is the most important information I should know about Lupron Depot?

    Your signs and symptoms may worsen during the first weeks of treatment. For patients who are at risk, treatment with Lupron daily injection (another form of Lupron) for the first 2 weeks may be an option.
  • Who should not take Lupron Depot?

    If you have experienced an allergic reaction to other drugs like Lupron Depot, you should not use this drug. Women should not use the dosages prescribed for men (see "What is the usual dosage?").
  • What should I tell my doctor before I take the first dose of Lupron Depot?

    Mention all prescription, over-the-counter, and herbal medications you are taking before beginning treatment with Lupron Depot. Also, talk to your doctor about your complete medical history, especially if you have metastatic spine cancer or urinary tract obstruction.
  • What is the usual dosage?

    The information below is based on the dosage guidelines your doctor uses. Depending on your condition and medical history, your doctor may prescribe a different regimen. Do not change the dosage or stop taking your medication without your doctor's approval.

    Adults: The recommended dose of Lupron Depot (7.5 mg) is one intramuscular injection once a month.

    The recommended dose of Lupron Depot-3 month (22.5 mg) is one intramuscular injection every 3 months (84 days).

    The recommended dose of Lupron Depot-4 month (30 mg) is one intramuscular injection every 4 months (16 weeks).

  • How should I take Lupron Depot?

    Lupron Depot should be administered under the supervision of your doctor. To help you remember when to receive each dose, mark your calendar to keep track of your office visits. It is important to receive this medication regularly to get the most benefit from it.
  • What should I avoid while taking Lupron Depot?

    Women should not take this form of Lupron Depot.
  • What are possible food and drug interactions associated with Lupron Depot?

    There are no known food or drug interactions with Lupron Depot.
  • What are the possible side effects of Lupron Depot?

    Side effects cannot be anticipated. If any develop or change in intensity, tell your doctor as soon as possible. Only your doctor can determine if it is safe for you to continue taking this drug.

    Side effects may include: hot flashes, sweats, pain, weakness, flu-like symptoms, headache, urinary symptoms, injection site reactions, swelling of the ankles or feet, tingling sensation (paresthesia), dizziness, decreased sexual desire or ability, shrinking of testicles

  • Can I receive Lupron Depot if I am pregnant or breastfeeding?

    Lupron Depot can cause serious harm to an unborn baby if taken during pregnancy. Women should not use this drug if they are pregnant or plan to become pregnant. Because it is unknown whether Lupron Depot is excreted in breast milk, women should not use this drug while breastfeeding.
  • What should I do if I miss a dose of Lupron Depot?

    If you miss a dose of Lupron Depot, make another appointment as soon as possible to establish a new schedule. It is important not to miss any doses.
  • How should I store Lupron Depot?

    Store at room temperature.