Generic Name: Triamterene

  • What is Maxzide?

    Maxzide is a combination of two diuretics (water pills) used in the treatment of high blood pressure and other conditions that require the elimination of excess fluid from the body.

  • What is the most important information I should know about Maxzide?

    If you have high blood pressure, you must take Maxzide regularly for it to be effective. Since blood pressure declines gradually, it may be several weeks before you get the full benefit of Maxzide; you must continue taking it even if you are feeling well. Maxzide does not cure high blood pressure; it merely keeps it under control.

    Abnormal elevations of potassium in your blood can occur with Maxzide. This is more likely to occur if you are elderly, severely ill, or have kidney problems or diabetes. Some warning signs include: fatigue, muscular weakness, numbness or tingling, paralysis of the hands or feet, and slow heart rate. Be sure to follow up with your doctor regularly to monitor your blood potassium level.

    In general, Maxzide may cause imbalances in blood electrolyte levels. Warning signs and symptoms of fluid and electrolyte imbalance include: decreased production of urine, drowsiness, dry mouth, fast heart rate, fatigue, low blood pressure, muscular fatigue, muscle pain or cramps, restlessness, stomach disturbances, thirst, or weakness. Stop taking Maxzide and speak to your doctor if you are experiencing any of these symptoms. Be sure to follow up with your doctor regularly to monitor your electrolytes.

  • Who should not take Maxzide?

    You should not take Maxzide if you are unable to urinate, or if you have any serious kidney disease, high potassium levels in your blood, or if you are taking other drugs that prevent the loss of potassium.

    If you are sensitive to or have ever had an allergic reaction to triamterene, hydrochlorothiazide, or sulfa drugs, you should not take this medication.

  • What should I tell my doctor before I take the first dose of Maxzide?

    Tell your doctor about all prescription, over-the-counter, and herbal medications you are taking before beginning treatment with this drug. Also, talk to your doctor about your complete medical history, especially if you have a history of any of the following: asthma, diabetes, gout (severe and painful inflammation of the joints), kidney disease, kidney stones, liver disease, cirrhosis (scarring) of the liver, or heart failure.

  • What is the usual dosage?

    The information below is based on the dosage guidelines your doctor uses. Depending on your condition and medical history, your doctor may prescribe a different regimen. Do not change the dosage or stop taking your medication without your doctor's approval.

    Adults: The usual dose is one tablet daily. If you have already been taking hydrochlorothiazide, your doctor will determine the appropriate dose for you.

  • How should I take Maxzide?

    Maxzide should be taken early in the day. To avoid stomach upset, take Maxzide with food.

  • What should I avoid while taking Maxzide?

    When taking Maxzide, do not use potassium-containing salt substitutes. Take potassium supplements only if specifically directed to by your doctor. Your potassium level should be checked frequently.

  • What are possible food and drug interactions associated with Maxzide?

    If Maxzide is taken with certain other drugs, the effects of either could be increased, decreased, or altered. It is especially important to check with your doctor before combining Maxzide with the following: blood pressure/heart medications known as ACE inhibitors and beta-blockers; lithium; nonsteroidal anti-inflammatory drugs such as indomethacin; drugs that minimize potassium loss; or drugs and salt substitutes that contain potassium.

  • What are the possible side effects of Maxzide?

    Side effects cannot be anticipated. If any develop or change in intensity, tell your doctor as soon as possible. Only your doctor can determine if it is safe for you to continue taking this drug.

    Side effects may include: anemia, change in potassium level (causing symptoms such as numbness, tingling, muscle weakness, slow heart rate, shock), difficulty breathing, dizziness, drowsiness, dry mouth, fatigue, headache, hives, impotence, irregular heartbeat, kidney stones, muscle cramps, nausea, rash, sensitivity to light, stomach irritations, urine discoloration, vomiting

  • Can I receive Maxzide if I am pregnant or breastfeeding?

    The effects of Maxzide during pregnancy have not been adequately studied. If you are pregnant or plan to become pregnant, inform your doctor immediately. Maxzide appears in breast milk and could affect a breastfeeding infant. Consult your doctor before breastfeeding.

  • What should I do if I miss a dose of Maxzide?

    If you miss a dose of this drug, skip it. Do not take two doses at once.

  • How should I store Maxzide?

    Store at room temperature.

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