Generic Name: Atovaquone

  • What is Mepron?

    Mepron is an antibiotic used for the prevention and treatment of Pneumocystis carinii pneumonia (PCP), a certain infection in the lungs that is more likely to occur in people infected with HIV (AIDS). Mepron is used to treat those who are intolerant to other medications.

  • What is the most important information I should know about Mepron?

    Take Mepron with meals. Food improves the absorption of this medication.

    Gastrointestinal (stomach and intestines) disorders can limit the absorption of Mepron. Tell your doctor if you have gastrointestinal problems.

    In rare cases, Mepron can cause liver diseases, hepatitis, and changes in the liver function tests. Tell your doctor if you have liver problems.

  • Who should not take Mepron?

    Do not take Mepron if you are allergic to it or any of its ingredients.

  • What should I tell my doctor before I take the first dose of Mepron?

    Tell your doctor about all prescription, over-the-counter, and herbal medications you are taking before beginning treatment with Mepron. Also, talk to your doctor about your complete medical history, especially if you have a liver disease, are pregnant, plan to become pregnant, or are breastfeeding.

  • What is the usual dosage?

    The information below is based on the dosage guidelines your doctor uses. Depending on your condition and medical history, your doctor may prescribe a different regimen. Do not change the dosage or stop taking your medication without your doctor's approval.

    Your doctor might prescribe different doses than listed below based on the type and severity of your infection.

    Prevention of PCP:

    Adults and children ≥13 years: The recommended dose is 1500 milligrams (mg), which is 10 milliliters (mL), once a day.

    Treatment of Mild-Moderate PCP:

    Adults and children ≥13 years: The recommended dose is 750 mg, which is 5 mL, twice a day for 21 days.

  • How should I take Mepron?

    Take Mepron exactly as prescribed by your doctor. Shake the bottle gently before using this suspension. Mepron should be taken with meals.

  • What should I avoid while taking Mepron?

    Do not take Mepron without meals.

  • What are possible food and drug interactions associated with Mepron?

    If Mepron is taken with certain other drugs, the effects of either could be increased, decreased, or altered. It is especially important to check with your doctor before combining Mepron with rifabutin or rifampin.

  • What are the possible side effects of Mepron?

    Side effects cannot be anticipated. If any develop or change in intensity, tell your doctor as soon as possible. Only your doctor can determine if it is safe for you to continue taking this drug.

    Side effects may include: allergic reactions, diarrhea, fever, headache, muscle pain, nausea, pain, rash, sweating, vomiting

  • Can I receive Mepron if I am pregnant or breastfeeding?

    The effects of Mepron during pregnancy and breastfeeding are unknown. Tell your doctor immediately if you are pregnant, plan to become pregnant, or are breastfeeding.

  • What should I do if I miss a dose of Mepron?

    If you miss a dose of Mepron, take it as soon as you remember. However, if it is almost time for your next dose, skip the one you missed and return to your regular dosing schedule. Do not take two doses at once.

  • How should I store Mepron?

    Store at room temperature. Do not freeze.