Generic Name: Pyridostigmine

  • What is Mestinon?

    Mestinon is a medicine used to treat myasthenia gravis. Mestinon is available in syrup, tablets, or extended-release tablets.

  • What is the most important information I should know about Mestinon?

    If you take too much Mestinon, you can develop serious side effects. Tell your doctor immediately if you experience increasing muscle weakness. This can also affect your respiratory (lung) muscles and cause life-threatening effects. Take Mestinon with caution if you have asthma or are taking atropine to work against the side effects of Mestinon.

  • Who should not take Mestinon?

    Do not use Mestinon if you are allergic to it or any of its ingredients, or if you have an intestinal or urinary blockage.

  • What should I tell my doctor before I take the first dose of Mestinon?

    Tell your doctor about all prescription, over-the-counter, and herbal medications you are taking before beginning treatment with Mestinon. Also, talk to your doctor about your complete medical history, especially if you have asthma, intestinal or urinary blockage, or kidney problems.

  • What is the usual dosage?

    The information below is based on the dosage guidelines your doctor uses. Depending on your condition and medical history, your doctor may prescribe a different regimen. Do not change the dosage or stop taking your medication without your doctor's approval.

    Syrup or Tablets

    Adults: The recommended dose is ten tablets or ten 5-milliliter teaspoonfuls of syrup every day, in divided doses spaced apart, based on your condition. Your doctor will adjust your dose and frequency depending on your needs.

    Extended-Release Tablets

    Adults: The recommended dose is 1-3 extended-release tablets 1-2 times a day, at least 6 hours apart from each other.

    If you have kidney impairment, your doctor will adjust your dose appropriately.

  • How should I take Mestinon?

    Take Mestinon exactly as prescribed by your doctor.

  • What should I avoid while taking Mestinon?

    Do not take more Mestinon than prescribed by your doctor.

  • What are possible food and drug interactions associated with Mestinon?

    If Mestinon is taken with certain other drugs, the effects of either could be increased, decreased, or altered. It is especially important to check with your doctor before combining Mestinon with atropine.

  • What are the possible side effects of Mestinon?

    Side effects cannot be anticipated. If any develop or change in intensity, tell your doctor as soon as possible. Only your doctor can determine if it is safe for you to continue taking this drug.

    Side effects may include: abdominal cramps, constriction of your pupils, diarrhea, excessive sweating, increased muscle contractions of your esophagus (the tube that connects your mouth and stomach) or intestines, increased salivation or lung secretions, muscle cramps, muscle twitch, muscle weakness, nausea, vomiting

  • Can I receive Mestinon if I am pregnant or breastfeeding?

    The effects of Mestinon during pregnancy and breastfeeding are unknown. Tell your doctor immediately if you are pregnant, plan to become pregnant, or are breastfeeding.

  • What should I do if I miss a dose of Mestinon?

    If you miss a dose of Mestinon, take it as soon as you remember. However, if it is almost time for your next dose, skip the one you missed and return to your regular dosing schedule. Do not take two doses at once.

  • How should I store Mestinon?

    Store at room temperature. Keep the tablets or extended-release tablets in a dry place.