Methadone Injection

Generic Name: Methadone

  • What is Methadone Injection?

    Methadone injection is a narcotic painkiller used to relieve moderate to severe pain. It is also used for the temporary treatment of opioid dependence when you are unable to take an oral medication. Methadone injection is administered intravenoulsy (through a vein in your arm), intramuscularly (injected into the muscle), or subcutaneously (just below the skin).

  • What is the most important information I should know about Methadone Injection?

    Methadone injection has abuse potential. Mental and physical dependence can occur when it is used improperly.

    Methadone injection can cause serious breathing problems that can become life-threatening, especially when it is used in the wrong way. Tell your doctor if you have any lung or breathing problems; your doctor will monitor you.

    Methadone injection can cause sudden fall in blood pressure. Tell your doctor immediately if you experience a fluttery or throbbing heartbeat, dizziness, lightheadedness, or fainting while receiving methadone injection.

  • Who should not take Methadone Injection?

    Your doctor will not administer methadone injection if you are allergic to it, any of its ingredients, to similar products, or if you have severe lung problems or severe asthma.

  • What should I tell my doctor before I take the first dose of Methadone Injection?

    Tell your doctor about all prescription, over-the-counter, and herbal medications you are taking before beginning treatment with methadone injection. Also, talk to your doctor about your complete medical history, especially if you have ever had kidney or liver disease, hypothyroidism (an underactive thyroid gland), heart disease, seizures, difficulty urinating, an enlarged prostate, a history of substance abuse or dependence, mental disorders (such as depression), urethral stricture (narrowing of the urethra, the tube that connects from the bladder to the genitals to lead urine out of your body), adrenal gland problems, low blood pressure, if you are taking medications to lower your blood pressure, or if you had a head injury.

  • What is the usual dosage?

    The information below is based on the dosage guidelines your doctor uses. Depending on your condition and medical history, your doctor may prescribe a different regimen. Do not change the dosage or stop taking your medication without your doctor's approval.

    Adults: Your doctor will prescribe and administer the appropriate dose for you based on your condition.

  • How should I take Methadone Injection?

    Your doctor will administer methadone injection to you.

  • What should I avoid while taking Methadone Injection?

    Do not use methadone injection with alcohol, other narcotic painkillers, tranquilizers (such as alprazolam or lorazepam), sedatives (such as diphenhydramine or phenobarbital), or other medications that slow down your brain function unless under the recommendation and guidance of your doctor.

    Methadone injection can impair your mental and physical ability to perform potentially hazardous tasks (such as driving or operating heavy machinery). Do not participate in any activities that require full alertness until you know how methadone injection affects you.

  • What are possible food and drug interactions associated with Methadone Injection?

    If methadone injection is used with certain other drugs, the effects of either could be increased, decreased, or altered. It is especially important to tell your doctor if you are taking any of the following prior to treatment with methadone injection: alcohol, antiarrhythmics (such as amiodarone, procainamide, or quinidine), antiviral medications (such as didanosine, efavirenz, lopinavir, nevirapine, ritonavir, stavudine, or zidovudine), azole antifungals (such as ketoconazole), carbamazepine, certain antidepressants (such as amitriptyline or desipramine), certain painkillers, macrolide antibiotics (such as erythromycin), phenytoin, rifampin, sedative-hypnotics, St. John's wort, or other medications that slow down your brain function (such as alprazolam, diazepam, or phenobarbital).

  • What are the possible side effects of Methadone Injection?

    Side effects cannot be anticipated. If any develop or change in intensity, tell your doctor as soon as possible. Only your doctor can determine if it is safe for you to continue taking this drug.

    Side effects may include: constipation, dizziness, dry mouth, headache, lightheadedness, loss of appetite, low blood pressure, nausea, rash, sedation, stomach pain, sweating, swelling, vomiting, weakness

  • Can I receive Methadone Injection if I am pregnant or breastfeeding?

    The effects of methadone injection during pregnancy and breastfeeding are unknown. Tell your doctor immediately if you are pregnant, plan to become pregnant, or are breastfeeding.

  • What should I do if I miss a dose of Methadone Injection?

    Do not miss your follow-up appointments with your doctor.

  • How should I store Methadone Injection?

    Your doctor will store this medication for you.