Generic Name: Methadone

  • What is Methadose?

    Methadose is used to treat moderate to severe pain in people who do not respond to other pain medicines, to control withdrawal symptoms in patients being treated for narcotic drug addiction, and to maintain treatment of narcotic drug addiction along with other social and medical services. Methadose contains methadone, which is a narcotic pain medicine similar to morphine.

    Methadose is a federally controlled substance because it has potential for abuse.

  • What is the most important information I should know about Methadose?

    Methadose can cause life-threatening breathing problems, which can lead to death. This risk is higher if you have never taken a narcotic pain medicine before. Breathing problems caused by Methadose may not happen right away. They could occur a while after you take a dose, even after pain has returned. It is very important to take Methadose exactly as your doctor has prescribed.

    Methadose can cause life-threatening heartbeat problems that can lead to death. Most of these problems have happened in people using large doses of Methadose for pain treatment.

    Methadose can cause sleepiness and may affect your ability to make decisions, think clearly, or react quickly. Do not drive, operate heavy machinery, or do other dangerous activities until you know how Methadose affects you.

    Methadose can cause your blood pressure to drop. This can make you feel dizzy and faint if you get up too fast from sitting or lying down. Low blood pressure is also more likely to happen if you take other medicines that can also lower your blood pressure.

  • Who should not take Methadose?

    Do not take Methadose if you are allergic to methadone or any other ingredients in Methadose.

    Do not take Methadose if you have severe asthma, severe lung problems, or if you have a blockage in your intestines.

  • What should I tell my doctor before I take the first dose of Methadose?

    Tell your doctor about all prescription, over-the-counter, and herbal medications you are taking before beginning treatment with Methadose. Also, talk to your doctor about your complete medical history, especially if you are taking medications for a mental condition, have a history of drug or alcohol abuse or addiction, a bowel blockage called paralytic ileus, Addison's disease (adrenal gland disease), difficulty urinating, enlarged prostate, head injuries, kidney or liver problems, lung disease, or breathing problems.

  • What is the usual dosage?

    The information below is based on the dosage guidelines your doctor uses. Depending on your condition and medical history, your doctor may prescribe a different regimen. Do not change the dosage or stop taking your medication without your doctor's approval.

    Adults: Your doctor will prescribe the appropriate dosage for you.

  • How should I take Methadose?

    Take Methadose exactly as prescribed by your doctor and follow his directions exactly. Your doctor may change your dose based on your reaction to the medicine. Do not change your dose unless your doctor tells you to change it. Do not take a higher dose of Methadose or take it more often than prescribed.

    If you take too much Methadose or overdose, call 911 or your local emergency number right away.

    Do not stop taking Methadose all at once if you have been taking it for more than a few days.

  • What should I avoid while taking Methadose?

    Do not drive, operate heavy machinery, or do other possibly dangerous activities until you know how Methadose affects you. Methadose can make you sleepy. Ask your doctor when it is okay to do these activities.

    Do not drink alcohol while using Methadose. It may increase the risk of dangerous side effects.

  • What are possible food and drug interactions associated with Methadose?

    If Methadose is taken with certain other drugs, the effects of either could be increased, decreased, or altered. It is especially important to check with your doctor before combining Methadose with other pain medications, abacavir, antidepressants including those in a class known as monoamine oxidase inhibitors, anxiety medicines, antihistamines, carbamazepine, didanosine, erythromycin, heart medications, ketoconazole, phenobarbital, rifampin, ritonavir, sleeping pills, St. John's wort, stavudine, tranquilizers, or zidovudine.

  • What are the possible side effects of Methadose?

    Side effects cannot be anticipated. If any develop or change in intensity, tell your doctor as soon as possible. Only your doctor can determine if it is safe for you to continue taking this drug.

    Side effects may include: constipation, dizziness, drowsiness, dry mouth, headache, lightheadedness, sweating, vomiting, weakness

    Stop taking Methadose immediately and call your doctor if you have: extreme drowsiness and slowed breathing, fast or slowed heartbeat, feelings of fainting, dizziness, confusion, or irregular heartbeat, slow shallow breathing, trouble breathing

  • Can I receive Methadose if I am pregnant or breastfeeding?

    The effects of Methadose on pregnancy are unknown, and it may pass into breast milk. Tell your doctor immediately if you are pregnant, plan to become pregnant, or are breastfeeding.

  • What should I do if I miss a dose of Methadose?

    If you miss a dose of Methadose, take the dose as soon as possible unless it is almost time for the next dose. Do not take two doses at once.

  • How should I store Methadose?

    Store at room temperature. Keep Methadose in a safe place away from children and protect from theft. Dispose of any unused Methadose remaining from a prescription as soon as they are no longer needed. Unused tablets should be flushed down the toilet.

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