Generic Name: Methyldopate

  • What is Methyldopate?

    Methyldopate is a medicine used intravenously (through a vein in your arm) to treat high blood pressure.

  • What is the most important information I should know about Methyldopate?

    Methyldopate can cause liver problems. If you develop a fever or jaundice (yellowing of the skin or whites of your eyes), contact your doctor.

    Methyldopate can increase your risk of developing hemolytic anemia (a blood disorder in which red blood cells are destroyed). Your doctor will monitor your blood counts while you are on methyldopate.

    Rarely, methyldopate can cause a reversible reduction in your white blood cell counts (cells that help to fight infections).

    Methyldopate contains sodium bisulfate. It can cause a severe allergic reaction if you have a sulfite allergy.

  • Who should not take Methyldopate?

    Do not take methyldopate if you are allergic to it or any of its ingredients.

    Do not take methyldopate if you have liver disease, or if you are on monoamine oxidase inhibitors (MAOIs), a class of drugs used to treat depression and other psychiatric conditions (such as phenelzine or tranylcypromine).

  • What should I tell my doctor before I take the first dose of Methyldopate?

    Tell your doctor about all prescription, over-the-counter, and herbal medications you are taking before beginning treatment with methyldopate. Also, talk to your doctor about your complete medical history, especially if you have liver, kidney, or heart disease, blood disorders (such as anemia), brain disorders, asthma, sulfite allergy, are pregnant, plan to become pregnant, or are breastfeeding.

  • What is the usual dosage?

    The information below is based on the dosage guidelines your doctor uses. Depending on your condition and medical history, your doctor may prescribe a different regimen. Do not change the dosage or stop taking your medication without your doctor's approval.

    Adults and children: Your doctor will administer the appropriate dose for you intravenously and will increase your dose as needed, until the desired effect is achieved.

    If you have kidney impairment, your doctor will adjust your dose appropriately.

  • How should I take Methyldopate?

    Your doctor will administer methyldopate to you and will monitor your blood pressure.

  • What should I avoid while taking Methyldopate?

    Do not miss your scheduled follow-up appointments with your doctor.

  • What are possible food and drug interactions associated with Methyldopate?

    If methyldopate is taken with certain other drugs, the effects of either could be increased, decreased, or altered. It is especially important tell your doctor if you are taking any of the following prior to treatment with methyldopate: lithium, MAOIs, or other blood pressure-lowering medications.

  • What are the possible side effects of Methyldopate?

    Side effects cannot be anticipated. If any develop or change in intensity, tell your doctor as soon as possible. Only your doctor can determine if it is safe for you to continue taking this drug.

    Side effects may include: constipation, diarrhea, fatigue, heart failure, rash, sudden fall in blood pressure, swelling, vomiting

  • Can I receive Methyldopate if I am pregnant or breastfeeding?

    The effects of methyldopate during pregnancy and breastfeeding are unknown. Tell your doctor immediately if you are pregnant, plan to become pregnant, or are breastfeeding.

  • What should I do if I miss a dose of Methyldopate?

    Methyldopate should be given under special circumstances determined by your doctor.

  • How should I store Methyldopate?

    Your doctor will store this medication for you.