Generic Name: Methylphenidate

  • What is Methylin?

    Methylin and Methylin ER are central nervous system stimulant medicines used to treat attention-deficit hyperactivity disorder (ADHD) and narcolepsy (a sleep disorder characterized by excessive daytime sleepiness).

  • What is the most important information I should know about Methylin?

    Methylin can cause sudden death in patients who have heart problems or heart defects, stroke and heart attack in adults, and increased blood pressure and heart rate. Your doctor will check you or your child carefully for heart problems before starting Methylin and will regularly check your blood pressure and heart rate. Tell your doctor immediately if you or your child has any signs of heart problems such as chest pain, shortness of breath, or fainting while taking Methylin.

    Tell your doctor about any mental problems you or your child have, or about a family history of suicide, bipolar illness, or depression. Tell your doctor immediately if you or your child have any new or worsening mental symptoms or problems while taking Methylin, especially seeing or hearing things that are not real, believing things that are not real, or are suspicious.

    Methylin is a federally controlled substance because it can be abused or lead to dependence. Keep Methylin in a safe place to prevent misuse and abuse. Selling or giving away Methylin can harm others, and is against the law.

    Tell your doctor if you, your child, or a family member has ever abused or been dependent on alcohol, prescription medicines, or street drugs.

  • Who should not take Methylin?

    Do not take Methylin if you are allergic to it, any of its ingredients, or to similar products. Also, do not take Methylin if you or your child are very anxious, tense, or agitated; have an eye problem called glaucoma (increased pressure in the eye); tics or Tourette's syndrome (a brain disorder characterized by involuntary movements and vocalizations called tics); severe high blood pressure or a heart problem; hyperthyroidism (an overactive thyroid gland); or have taken an antidepression medication known as a monoamine oxidase inhibitor (MAOIs) (such as phenelzine or tranylcypromine) within the past 14 days.

    Do not give Methylin to children less than 6 years old.

  • What should I tell my doctor before I take the first dose of Methylin?

    Tell your doctor about all prescription, over-the-counter, and herbal medications you are taking before beginning treatment with Methylin. Also, talk to your doctor about your complete medical history, especially if you or your child have heart problems, heart defects, or high blood pressure; mental problems including psychosis, mania, bipolar illness, or depression; tics or Tourette's syndrome, seizures, or have had an abnormal brain wave test (electroencephalogram).

  • What is the usual dosage?

    The information below is based on the dosage guidelines your doctor uses. Depending on your condition and medical history, your doctor may prescribe a different regimen. Do not change the dosage or stop taking your medication without your doctor's approval.


    Adults: The usual dose is 20-30 milligrams (mg) a day in divided doses two or three times a day.

    Children ≥6 years: The usual starting dose is 5 mg twice a day, before breakfast and lunch.

    Your doctor or your child's doctor will prescribe the appropriate dose and will adjust the dose as needed, until the desired effect is achieved.

    Methylin ER

    Adults and children ≥6 years: These are extended-release tablets that keep working for 8 hours. They may be used in place of Methylin tablets and your doctor will determine the appropriate dose. Your child's doctor will decide if these extended-release tablets should be used in place of the regular tablets.

  • How should I take Methylin?

    Take Methylin exactly as prescribed by your doctor. Do not take extra doses or take more often without asking your doctor. Take Methylin 30-45 minutes before a meal.

    Do not chew or crush Methylin ER tablets; swallow them whole with water or other liquids. Tell your doctor if you or your child cannot swallow Methylin ER tablets whole; a different medicine may need to be prescribed.

  • What should I avoid while taking Methylin?

    Methylin can cause visual disturbances, such as blurred vision. Do not drive or operate dangerous machinery until you know how this medication affects you.

    Do not take Methylin within 14 days of taking an MAOI.

  • What are possible food and drug interactions associated with Methylin?

    If Methylin is taken with certain other drugs, the effects of either could be increased, decreased, or altered. It is especially important to check with your doctor before combining Methylin with any of the following: antidepressants, blood pressure medicines, blood thinners (such as warfarin), clonidine, cold and allergy medicines that contain decongestants, MAOIs, phenylbutazone, seizure medications (such as phenobarbital or phenytoin).

  • What are the possible side effects of Methylin?

    Side effects cannot be anticipated. If any develop or change in intensity, tell your doctor as soon as possible. Only your doctor can determine if it is safe for you to continue taking this drug.

    Side effects may include: decreased appetite, dizziness, eyesight changes or blurred vision, headache, nervousness, seizures, slowing of growth in children, stomach ache, trouble sleeping

  • Can I receive Methylin if I am pregnant or breastfeeding?

    The effects of Methylin during pregnancy and breastfeeding are unknown. Tell your doctor immediately if you are pregnant, plan to become pregnant, or are breastfeeding.

  • What should I do if I miss a dose of Methylin?

    If you miss a dose of Methylin, take it as soon as you remember. However, if it is almost time for your next dose, skip the one you missed and return to your regular dosing schedule. Do not take two doses at once.

  • How should I store Methylin?

    Store at room temperature.