Metozolv ODT

Generic Name: Metoclopramide

  • What is Metozolv ODT?

    Metozolv ODT is a medicine used as a short-term treatment to relieve the heartburn symptoms of gastroesophageal reflux disease (GERD) when certain other treatments do not work. Also, Metozolv ODT is used to relieve the symptoms of diabetic gastroparesis (slow stomach emptying in people with diabetes).

  • What is the most important information I should know about Metozolv ODT?

    Metozolv ODT can cause tardive dyskinesia (abnormal muscle movements, including tremor, shuffling, and uncontrolled, involuntary movements) which happens mostly in your face muscles. Also, Metozolv ODT can cause uncontrolled spasms of your muscles or Parkinson's-like symptoms. Tell your doctor immediately if you have movements that you cannot stop or control (such as lip smacking or puckering, chewing, frowning or scowling, sticking out your tongue, blinking and moving your eyes, body stiffness, or shaking of your arms and legs).

    In rare cases, Metozolv ODT can cause neuroleptic malignant syndrome (NMS) (a life-threatening brain disorder). NMS is a medical emergency. Tell your doctor immediately if you experience a high fever, muscle rigidity, confusion, fast or irregular heartbeats, changes in your blood pressure, or sweating more than usual.

    Metozolv ODT can cause serious side effects, such as depression or thoughts about suicide, high blood pressure, or excessive body water. Tell your doctor if you have or had a history of depression or mental illness, high blood pressure, liver problems, heart failure or heart rhythm problems.

    After you stop taking Metozolv ODT, you can experience withdrawal symptoms, such as dizziness, nervousness, or headaches.

  • Who should not take Metozolv ODT?

    Do not take Metozolv ODT if you are allergic to it or any of its ingredients.

    Do not take Metozolv ODT if you have stomach or intestine problems, pheochromocytoma (tumor of the adrenal gland), or seizures.

    Do not take Metozolv ODT if you take other medicines that can cause uncontrolled movements.

  • What should I tell my doctor before I take the first dose of Metozolv ODT?

    Tell your doctor about all prescription, over-the-counter, and herbal medications you are taking before beginning treatment with Metozolv ODT. Also, talk to your doctor about your complete medical history, especially if you have kidney or liver disease, depression or mental illness, high blood pressure, heart failure or heart rhythm problems, diabetes, or Parkinson's disease.

  • What is the usual dosage?

    The information below is based on the dosage guidelines your doctor uses. Depending on your condition and medical history, your doctor may prescribe a different regimen. Do not change the dosage or stop taking your medication without your doctor's approval.


    Adults: The recommended dose is 10-15 milligrams (mg) up to four times a day. Your doctor will prescribe the appropriate dose for you based on your condition.

    Diabetic Gastroparesis

    Adults: The recommended dose is 10 mg up to four times a day.

  • How should I take Metozolv ODT?

    Take Metozolv ODT exactly as prescribed by your doctor. Metozolv ODT comes as a tablet that melts in your mouth in about one minute. Take this medication at least 30 minutes before eating and at bedtime. Handle this medication with dry hands. If the tablet breaks or crumbles while you are handling it, discard it, and take a new tablet. Do not take Metozolv ODT for more than 12 weeks.

    Please review the instructions that came with your prescription on how to properly take Metozolv ODT.

  • What should I avoid while taking Metozolv ODT?

    Do not drink alcohol while you are taking Metozolv ODT. Alcohol can worsen some side effects, such as feeling sleepy.

    Do not drive, work with machines, or engage in dangerous tasks until you know how Metozolv ODT affects you. This medication can cause sleepiness.

  • What are possible food and drug interactions associated with Metozolv ODT?

    If Metozolv ODT is taken with certain other drugs, the effects of either could be increased, decreased, or altered. It is especially important to check with your doctor before combining Metozolv ODT with the following: acetaminophen; alcohol; blood pressure/heart medications (such as lisinopril or metoprolol); central nervous system (CNS) depressants (such as alprazolam, chlordiazepoxide, or phenobarbital); certain antipsychotic medications (such as haloperidol, loxapine, or paliperidone); cyclosporine; digoxin; insulin; levodopa; monoamine oxidase inhibitors (MAOIs), a class of drugs used to treat depression and other psychiatric conditions (such as phenelzine); other medicines that contain metoclopramide (such as Reglan, Reglan ODT, or metoclopramide syrup); or tetracycline.

  • What are the possible side effects of Metozolv ODT?

    Side effects cannot be anticipated. If any develop or change in intensity, tell your doctor as soon as possible. Only your doctor can determine if it is safe for you to continue taking this drug.

    Side effects may include: dizziness, headache, nausea, restlessness, sleepiness, tiredness, vomiting

  • Can I receive Metozolv ODT if I am pregnant or breastfeeding?

    The effects of Metozolv ODT during pregnancy are unknown. Metozolv ODT can cause harm to your baby if you use this medication during breastfeeding. Do not take Metozolv ODT while you are breastfeeding. Tell your doctor immediately if you are pregnant, plan to become pregnant, or are breastfeeding.

  • What should I do if I miss a dose of Metozolv ODT?

    If you miss a dose of Metozolv ODT, take it as soon as you remember. However, if it is almost time for your next dose, skip the one you missed and return to your regular dosing schedule. Do not take two doses at once.

  • How should I store Metozolv ODT?

    Store at room temperature. Protect from moisture.