Generic Name: Hydrochlorothiazide

  • What is Microzide?

    Microzide belongs to a class of medications called diuretics (water pills); it is used alone or in combination with other medications to treat high blood pressure.

  • What is the most important information I should know about Microzide?

    Microzide can cause eye disorders, including nearsightedness and glaucoma (high pressure in the eye). Stop taking Microzide and tell your doctor if you experience a blurred vision, eye pain, or any other visual changes.

    Changes in body electrolytes (chemicals that are important for the cells in your body to function, such as sodium and potassium) and body fluids can occur with Microzide. Tell your doctor if you develop dry mouth, thirst, weakness, tiredness, drowsiness, restlessness, muscle pains or cramps, muscle tiredness, dizziness or fainting, low or no urine output, fast heartbeat, or nausea and vomiting.

    Microzide can cause low blood potassium levels, which can affect the heart and cause irregular heartbeat. Take potassium supplements or increase your intake of potassium-rich foods. Also, the risk for low blood sodium levels can increase in hot weather. Tell your doctor if you will be exposed to high temperatures.

    Microzide can increase your blood sugar levels. If you have diabetes, check your blood sugar levels regularly. Ask your doctor before you change the dose of your diabetes medicine.

    Microzide can cause low blood pressure, dizziness, or blurred vision. These effects can be worsened when taken with alcohol or certain other medicines.

  • Who should not take Microzide?

    Do not take Microzide if you are allergic to it, any of its ingredients, or sulfonamide medications (such as sulfamethoxazole). In addition, do not take Microzide if you have low or no urine output.

  • What should I tell my doctor before I take the first dose of Microzide?

    Tell your doctor about all prescription, over-the-counter, and herbal medications you are taking before beginning treatment with Microzide. Also, talk to your doctor about your complete medical history, especially if you have a kidney problem, history of allergy or bronchial asthma, history of sulfonamide or penicillin allergy, liver problems, diabetes, edema (swelling), gout (severe and painful inflammation of the joints), parathyroid gland problems, are pregnant, plan to become pregnant, or are breastfeeding.

  • What is the usual dosage?

    The information below is based on the dosage guidelines your doctor uses. Depending on your condition and medical history, your doctor may prescribe a different regimen. Do not change the dosage or stop taking your medication without your doctor's approval.

    Adults: The usual starting dose is 12.5 milligrams (mg) once a day. Your doctor will prescribe the appropriate dose for you and will increase your dose as needed.

  • How should I take Microzide?

    Take Microzide exactly as prescribed by your doctor.

  • What should I avoid while taking Microzide?

    Do not drink alcohol while you are taking Microzide.

  • What are possible food and drug interactions associated with Microzide?

    If Microzide is taken with certain other drugs, the effects of either could be increased, decreased, or altered. It is especially important to check with your doctor before combining Microzide with the following: alcohol, barbiturates (such as phenobarbital), cholestyramine, colestipol, corticosteroids (such as prednisone), diabetes medicines (including insulin), diuretics (water pills), lithium, narcotic painkillers (such as morphine), nonsteroidal anti-inflammatory drugs (NSAIDs) (such as indomethacin), or other blood pressure medications.

  • What are the possible side effects of Microzide?

    Side effects cannot be anticipated. If any develop or change in intensity, tell your doctor as soon as possible. Only your doctor can determine if it is safe for you to continue taking this drug.

    Side effects may include: allergic reactions, dizziness, electrolyte imbalance, fainting, headache, impotence, jaundice (yellowing of the skin or whites of the eyes), low blood pressure, muscle spasms, numbness or tingling of your skin, pancreatitis (inflammation of the pancreas), rash, restlessness, temporary blurred vision, vomiting, weakness

  • Can I receive Microzide if I am pregnant or breastfeeding?

    The effects of Microzide during pregnancy and breastfeeding are unknown. Tell your doctor immediately if you are pregnant, plan to become pregnant, or are breastfeeding.

  • What should I do if I miss a dose of Microzide?

    If you miss a dose of Microzide, take it as soon as you remember. However, if it is almost time for your next dose, skip the one you missed and return to your regular dosing schedule. Do not take two doses at once.

  • How should I store Microzide?

    Store at room temperature. Protect from light, moisture, and freezing.