Mirapex ER

Generic Name: Pramipexole

  • What is Mirapex ER?

    Mirapex ER is a medicine used to treat the signs and symptoms of Parkinson's disease.

  • What is the most important information I should know about Mirapex ER?

    Read the Patient Information that comes with Mirapex ER tablets before you start taking it and each time you refill your prescription. The information may have changed. The leaflet does not take the place of discussions with your doctor about your medical condition or treatment.

    Pramipexole is the active ingredient that is in both Mirapex ER (extended release) tablets and Mirapex (immediate release) tablets. Do not take both Mirapex ER and Mirapex.

    If you have Parkinson's disease and are stopping Mirapex ER tablets, you should stop Mirapex ER slowly over 7 days. Do not suddenly stop taking Mirapex ER without talking to your doctor. If you stop this medicine suddenly, you may develop fever, confusion, or severe muscle stiffness. Tell your doctor immediately if you stop taking Mirapex ER for any reason. Do not start taking Mirapex ER again before speaking with your doctor.

    Mirapex ER can cause you to fall asleep (even when you don't feel sleepy) while you are doing daily activities such as driving, talking with other people, or eating. You can fall asleep without any warning. Do not drive a car, operate a machine, or do anything that needs you to be alert until you know how Mirapex ER affects you.

    Mirapex ER can cause hallucinations (such as unreal visions, sounds, or sensations). The chances of having hallucinations are higher if you have Parkinson's disease and are elderly (≥65 years). If you experience hallucinations, tell your doctor immediately.

    Mirapex ER can cause you to have unusual urges such as gambling, compulsive eating, compulsive buying, and increased sex drive. If you or your family members notice that you are developing unusual urges or behavior, tell your doctor immediately.

  • Who should not take Mirapex ER?

    Do not take Mirapex ER if you are allergic to it, any of its ingredients, or to similar products.

  • What should I tell my doctor before I take the first dose of Mirapex ER?

    Tell your doctor about all prescription, over-the-counter, and herbal medications you are taking before beginning treatment with Mirapex ER. Also, talk to your doctor about your complete medical history, especially if you feel sleepy during the day, use medications that make you sleepy; are taking medications that your doctor informs you may increase the effects of Mirapex ER, or drink alcohol; have low blood pressure, feel dizzy, or faint (especially when getting up from a lying or sitting position); have sleep disorders; have trouble controlling your muscles; or have kidney problems.

  • What is the usual dosage?

    The information below is based on the dosage guidelines your doctor uses. Depending on your condition and medical history, your doctor may prescribe a different regimen. Do not change the dosage or stop taking your medication without your doctor's approval.

    Adults: The starting dose is 0.375 milligrams (mg) once a day. Your dose may be increased gradually, not more often than every 5-7 days.

    Your doctor will prescribe the appropriate dose for you and will increase your dose as needed, until the desired effect is achieved.

  • How should I take Mirapex ER?

    Take Mirapex ER exactly as prescribed by your doctor. Do not take extra doses or take more often without asking your doctor.

    Take Mirapex ER with or without food. Taking Mirapex ER with food can lower your chances of getting nausea.

    Swallow Mirapex ER tablets whole. Do not chew, crush, or divide the tablets.

  • What should I avoid while taking Mirapex ER?

    Do not take Mirapex ER for another condition or give the medicine to others.

    Do not drive a car, operate a machine, or do anything that needs you to be alert until you know how Mirapex ER affects you. Sleepiness caused by Mirapex ER may first occur as late as one year after you start your treatment.

    Do not drink alcohol while you are taking Mirapex ER.

  • What are possible food and drug interactions associated with Mirapex ER?

    If Mirapex ER is taken with certain other drugs, the effects of either could be increased, decreased, or altered. It is especially important to check with your doctor before combining Mirapex ER with the following: alcohol, cimetidine, metoclopramide, or medications that affect your brain function (such as butyrophenones, phenothiazines, or thioxanthenes).

  • What are the possible side effects of Mirapex ER?

    Side effects cannot be anticipated. If any develop or change in intensity, tell your doctor as soon as possible. Only your doctor can determine if it is safe for you to continue taking this drug.

    Side effects may include: constipation, dizziness, hallucinations, headache, loss of appetite, low blood pressure when you sit or stand up quickly, nausea, sleepiness, tiredness, vomiting

  • Can I receive Mirapex ER if I am pregnant or breastfeeding?

    The effects of Mirapex ER during pregnancy and breastfeeding are unknown. Tell your doctor immediately if you are pregnant, plan to become pregnant, or are breastfeeding.

  • What should I do if I miss a dose of Mirapex ER?

    If you miss a dose of Mirapex ER, take it as soon as you remember. However, if it is almost time for your next dose, skip the one you missed and return to your regular dosing schedule. Do not take two doses at once.

  • How should I store Mirapex ER?

    Store at room temperature.