Generic Name: Isosorbide

  • What is Monoket?

    Monoket is a medicine used to prevent and treat angina (chest pain) caused by coronary artery disease.

  • What is the most important information I should know about Monoket?

    Monoket can cause a severe decrease in blood pressure. This is most likely to occur while rising from a seated position. This effect can occur more frequently if you consume alcohol. Tell your doctor immediately if you experience dizziness or lightheadedness.

    Headache is a common side effect of Monoket. If you get headaches while you are using Monoket, this is sign that the medicine is working properly. You should not try to avoid headaches by changing the time you take Monoket. Aspirin or acetaminophen (Tylenol) may relieve the pain.

  • Who should not take Monoket?

    Do not take Monoket if you are allergic to it, any of its ingredients, or other nitrates or nitrites.

  • What should I tell my doctor before I take the first dose of Monoket?

    Tell your doctor about all prescription, over-the-counter, and herbal medications you are taking before beginning treatment with Monoket. Also, talk to your doctor about your complete medical history, especially if you are allergic to nitrates, have heart failure or any other heart condition, are pregnant, plan to become pregnant, or are breastfeeding.

  • What is the usual dosage?

    The information below is based on the dosage guidelines your doctor uses. Depending on your condition and medical history, your doctor may prescribe a different regimen. Do not change the dosage or stop taking your medication without your doctor's approval.

    Adults: The recommended dose is 20 milligrams (mg) twice a day, with doses 7 hours apart.

  • How should I take Monoket?

    Take Monoket exactly as prescribed by your doctor. You can take the first dose on awakening and the second dose 7 hours later.

  • What should I avoid while taking Monoket?

    Do not consume alcohol while you are taking Monoket.

  • What are possible food and drug interactions associated with Monoket?

    If Monoket is taken with certain other drugs, the effects of either could be increased, decreased, or altered. It is especially important to check with your doctor before combining Monoket with the following: alcohol, blood pressure/heart medications known as calcium channel blockers (such as amlodipine), or sildenafil.

  • What are the possible side effects of Monoket?

    Side effects cannot be anticipated. If any develop or change in intensity, tell your doctor as soon as possible. Only your doctor can determine if it is safe for you to continue taking this drug.

    Side effects may include: abdominal pain, allergic reactions, chest pain, cough, decrease in blood pressure, diarrhea, dizziness, flushing, headache, irregular heartbeat, lightheadedness, nausea, rash, tiredness

  • Can I receive Monoket if I am pregnant or breastfeeding?

    The effects of Monoket during pregnancy and breastfeeding are unknown. Tell your doctor immediately if you are pregnant, plan to become pregnant, or are breastfeeding.

  • What should I do if I miss a dose of Monoket?

    If you miss a dose of Monoket, take it as soon as you remember. However, if it is almost time for your next dose, skip the one you missed and return to your regular dosing schedule. Do not take two doses at once.

  • How should I store Monoket?

    Store at room temperature.