Generic Name: Fosinopril

  • What is Monopril?

    Monopril is a type of medication known as an angiotensin converting enzyme (ACE) inhibitor. It is used to lower your blood pressure when taken alone or in combination with other medications. Monopril is also prescribed to help manage heart failure in combination with diuretics (water pills), with or without digitalis.

  • What is the most important information I should know about Monopril?

    If taken during the second or third trimester of pregnancy, Monopril can cause serious harm or even death to an unborn baby. If you become pregnant while taking Monopril, you should stop taking Monopril immediately and tell your doctor right away.

    Monopril can cause angioedema, a rare but serious allergic reaction leading to extreme swelling of the face, lips, tongue, throat (causing difficulty breathing), or gut (causing severe abdominal pain). If you experience any of these symptoms, you should stop taking the medication and seek emergency medical attention right away.

    Make sure your doctor knows if you have any type of liver impairment or injury. Rarely, Monopril may cause a yellowing of the skin or eyes, which can be a sign of liver injury. If this occurs, tell your doctor immediately.

    Monopril may cause lightheadedness or fainting, especially upon standing from a lying or sitting position. If this occurs, tell your doctor immediately.

    If you get any type of infection (sore throat/fever) that does not go away while taking Monopril, report it to your doctor immediately.

    Use Monopril with caution if you have congestive heart failure or kidney disease. Patients with heart conditions need to be careful, as this medication may cause an excessive drop in blood pressure. Your doctor may need to monitor you for the first 2 weeks of therapy. Patients on dialysis need to be careful as the use of this drug may lead to a severe allergic reaction.

    Avoid becoming dehydrated to prevent a serious drop in your blood pressure. This can occur with excessive sweating, vomiting, or diarrhea.

  • Who should not take Monopril?

    You should not take Monopril if you have had a previous allergic reaction or are sensitive to Monopril or any other ACE inhibitor.

    You should not take Monopril if you are pregnant. If you become pregnant, stop taking the drug and contact your doctor.

  • What should I tell my doctor before I take the first dose of Monopril?

    Tell your doctor about all prescription, over-the-counter, and herbal medications you are taking before beginning treatment with Monopril. Also, talk to your doctor about your complete medical history, especially if you are pregnant or plan to become pregnant, have congestive heart failure, liver or kidney disease, or if you have ever had an allergy or sensitivity to an ACE inhibitor, such as Monopril.

  • What is the usual dosage?

    The information below is based on the dosage guidelines your doctor uses. Depending on your condition and medical history, your doctor may prescribe a different regimen. Do not change the dosage or stop taking your medication without your doctor's approval.

    Blood Pressure

    Adults: The usual starting dose is 10 milligrams (mg) once a day. The usual maintenance dose is 20-40 mg taken once daily; however, your doctor may increase your dose, up to 80 mg once a day, based on your condition.

    Children: Your doctor will prescribe the appropriate dose for your child based on their weight.

    Heart Failure

    Adults: The usual starting dose is 10 mg once a day. Your doctor will likely observe you at this dose and may increase your daily dose over several weeks, up to 20-40 mg once a day.

  • How should I take Monopril?

    Monopril can be taken with or without food, and should be taken at the same time every day.

  • What should I avoid while taking Monopril?

    Avoid driving or operating heavy machinery until you know how Monopril will affect you. Avoid becoming dehydrated and drink adequate fluids while taking Monopril to prevent a serious drop in blood pressure.

  • What are possible food and drug interactions associated with Monopril?

    If Monopril is taken with certain other drugs, the effects of either could be increased, decreased, or altered. It is especially important to check with your doctor before combining Monopril with the following: antacids, injectable gold products, lithium, certain diuretics (water pills) such as spironolactone, amiloride and triamterene, potassium supplements, or salt substitutes containing potassium.

  • What are the possible side effects of Monopril?

    Side effects cannot be anticipated. If any develop or change in intensity, tell your doctor as soon as possible. Only your doctor can determine if it is safe for you to continue taking this drug.

    Side effects may include: dizziness, cough, low blood pressure, muscle pain, nausea and vomiting, diarrhea, chest pain, upper respiratory infection

  • Can I receive Monopril if I am pregnant or breastfeeding?

    Monopril should not be taken during pregnancy. Taking Monopril while you are pregnant could cause serious harm or even death to your unborn baby. Monopril is excreted in breast milk, and should not be taken if you are breastfeeding. Tell your doctor immediately if you are pregnant, plan to become pregnant, or are breastfeeding.

  • What should I do if I miss a dose of Monopril?

    If you forget to take Monopril, skip the dose you missed and then return to your normal dosing schedule. Do not take two doses at once.

  • How should I store Monopril?

    Store at room temperature.

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