What is MS Contin?MS Contin is a narcotic pain medication that releases its active ingredient (morphine) slowly for the management of moderate to severe pain when a continuous, around-the-clock opioid painkiller is needed for an extended period of time.
What is the most important information I should know about MS Contin?MS Contin has the potential for dependence and abuse and can cause severe adverse effects including respiratory depression and even death if not taken according to your doctor's directions, especially if you have never been exposed to opioids, are elderly or debilitated, or have conditions that can cause you to become oxygen depleted. It is NOT intended for use on an as-needed basis. Use MS Contin exactly the way your doctor tells you to, and it should only be used for the condition for which it was prescribed.
MS Contin 100- and 200-milligram (mg) tablets are only for use in patients who have already been taking opioid drugs (opioid-tolerant). Use by patients who have not been taking an opioid drug can cause fatal respiratory depression.
Call your doctor right away if you experience any pain or side effects while taking MS Contin. Individualization of dosage is essential to make optimal use of this medication.
Who should not take MS Contin?Do not take MS Contin if you are allergic or sensitive to morphine or any ingredient in MS Contin, have a blockage of the bowel, or have severe lung problems, including decreased breathing capacity, asthma, or high levels of carbon dioxide in the blood.
What should I tell my doctor before I take the first dose of MS Contin?Tell your doctor about all prescription, over-the-counter, and herbal medications you are taking before beginning treatment with MS Contin. Also, talk to your doctor about your complete medical history, especially if you have severe liver, lung, or kidney impairment; thyroid disease; adrenocortical insufficiency (e.g., Addison's Disease); history of head injury, CNS depression, or coma; psychosis; prostate enlargement, or urethral stricture; acute alcoholism; a spinal condition called kyphoscoliosis; lung problems; seizure disorders; low blood pressure or if you are taking medications to lower your blood pressure; stomach problems; history of substance abuse or drug addiction; or an inability to swallow. Also, tell your doctor if you are pregnant, plan to become pregnant, or are breastfeeding.
What is the usual dosage?The information below is based on the dosage guidelines your doctor uses. Depending on your condition and medical history, your doctor may prescribe a different regimen. Do not change the dosage or stop taking your medication without your doctor's approval.
Adults: Your doctor will prescribe the appropriate dosage for you based on your condition and past medication history.
MS Contin 100- and 200-mg tablets are only to be taken by patients who are tolerant of daily doses of morphine of ≥200 mg for the 100-mg tablet or ≥400 mg for the 200-mg tablet.
How should I take MS Contin?MS Contin tablets should be swallowed whole and never chewed or crushed. Taking broken, chewed, dissolved, or crushed MS Contin tablets leads to potentially fatal doses of morphine.
Take MS Contin exactly as directed by your doctor. Do not adjust the dose or discontinue MS Contin without consulting your doctor. Contact your doctor if you feel that discontinuation of therapy is appropriate; your doctor can provide a dose schedule to accomplish a gradual discontinuation of the medication, if necessary.
What should I avoid while taking MS Contin?Do not drink alcohol or take sleeping aids while taking MS Contin.
MS Contin may impair mental and/or physical alertness. Do not drive or operate heavy machinery until you are aware of how MS Contin affects you.
Do not share this medication with others.
What are possible food and drug interactions associated with MS Contin?If MS Contin is taken with certain other drugs, the effects of either could be increased, decreased, or altered. It is especially important to check with your doctor before combining MS Contin with the following: alcohol; pain relievers such as pentazocine, nalbuphine, butorphanol, or buprenorphine; general anesthetics; phenothiazine-type medications; sedatives; and tranquilizers.
What are the possible side effects of MS Contin?Side effects cannot be anticipated. If any develop or change in intensity, tell your doctor as soon as possible. Only your doctor can determine if it is safe for you to continue taking this drug.
Side effects may include: constipation, lightheadedness, dizziness, lethargy, nausea, vomiting, sweating, euphoria, negative mood changes
Can I receive MS Contin if I am pregnant or breastfeeding?You should not take MS Contin during pregnancy unless your doctor instructs you to and is aware that you are pregnant. Discuss with your doctor if you are pregnant or planning to become pregnant while using MS Contin. MS Contin is found in breast milk; you should not breastfeed while taking this medicine.
What should I do if I miss a dose of MS Contin?If you miss a dose of MS Contin, take the missed dose as soon as possible. However, if it is almost time for your next dose, skip the one you missed and go back to your regular dosing schedule. Do not take two doses at once. If you are unsure, ask your doctor or pharmacist for advice.
How should I store MS Contin?Store at room temperature in a secure place out of reach of children. Protect from light. Dispose of unused tablets by flushing them down the toilet. Protect from theft.
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