Generic Name: Alprostadil

  • What is Muse?

    Muse is a medicated transurethral delivery system (inserted into the urethra) that is used to treat erectile dysfunction for men (inability to attain or maintain an erection for sexual intercourse), commonly called impotence.

  • What is the most important information I should know about Muse?

    Muse can decrease your blood pressure and can cause you to faint. Do not drive or perform other hazardous activities while you are taking this medication until you know how Muse affects you. Also, tell your doctor if you are taking any medications to treat high blood pressure.

    Muse can cause painful, prolonged erections. Tell your doctor immediately if your erection is rigid for more than 4 hours.

    Muse will not protect you or your partner from sexually transmitted diseases, such as chlamydia, gonorrhea (a sexually transmitted disease characterized by itching and burning during urination), herpes simplex virus, viral hepatitis, human immunodeficiency virus (HIV or AIDS), human papilloma virus (genital warts), or syphilis.

  • Who should not take Muse?

    Muse is not for use in women or children.

    Do not use Muse if you have an abnormally formed penis or if you have been advised not to undertake sexual activity.

    Do not use Muse if you have conditions that make you more prone to blood clots, such as sickle cell anemia or tumor of the bone marrow (multiple myeloma). These conditions increase your risk of having a painful, prolonged erection.

    Do not use Muse for sexual intercourse with a pregnant woman unless you use a condom barrier.

    Do not use Muse if you are allergic to it or any of its ingredients.

  • What should I tell my doctor before I take the first dose of Muse?

    Tell your doctor about all prescription, over-the-counter, and herbal medications you are taking before beginning treatment with Muse. Also, talk to your doctor about your complete medical history, especially if you have lung disease, an abnormally formed penis, bleeding problems, blood disorders such as sickle cell anemia, leukemia, or multiple myeloma.

  • What is the usual dosage?

    The information below is based on the dosage guidelines your doctor uses. Depending on your condition and medical history, your doctor may prescribe a different regimen. Do not change the dosage or stop taking your medication without your doctor's approval.

    Adults: The recommended starting dose is 125 milligrams (mg) or 250 mg as needed for a sufficient erection. Your doctor will prescribe the appropriate dose for you and will increase your dose as needed, until the desired effect is achieved.

  • How should I take Muse?

    Use Muse as prescribed by your doctor. Muse is inserted through the urethra. Your doctor should instruct you on the proper technique for inserting Muse. An erection should begin within 5-10 minutes after inserting Muse. Sit, or preferably stand, or walk about 10 minutes while the erection is developing. This increases the blood flow to the penis and will enhance your erection. The effect of Muse is expected to last for 30-60 minutes, but the actual duration will vary. Each Muse is for single use only. Properly discard it after using it.

    Please review the instructions that came with your prescription on how to properly use Muse.

  • What should I avoid while taking Muse?

    Do not drive or perform other hazardous activities until you know how Muse affects you.

    Do not sleep or lay on your back after inserting Muse. Doing so can decrease the effect of Muse.

    Do not use more than two doses of Muse per day.

  • What are possible food and drug interactions associated with Muse?

    No significant interactions have been reported with Muse at this time. However, always yell your doctor about any medicines you take, including over-the-counter medications, vitamins, and herbal supplements.

  • What are the possible side effects of Muse?

    Side effects cannot be anticipated. If any develop or change in intensity, tell your doctor as soon as possible. Only your doctor can determine if it is safe for you to continue taking this drug.

    Side effects may include: aching in the penis, testicles, legs, and in the area between the penis and rectum; dizziness; fainting; lightheadedness; minor urethral bleeding or spotting; prolonged erection; rapid heartbeat; redness of the penis; swelling of the leg veins; warmth or burning sensation in the urethra

  • Can I receive Muse if I am pregnant or breastfeeding?

    Muse is intended for use only by men and must not be used by women.

  • What should I do if I miss a dose of Muse?

    Muse should be given under special circumstances or given only as needed.

  • How should I store Muse?

    Store in the refrigerator, or store at room temperature for up to 14 days. When traveling, store Muse in a portable ice pack or cooler. Do not store in a car or in baggage storage areas where Muse may be exposed to extremes in temperature.