Generic Name: Rifabutin

  • What is Mycobutin?

    Mycobutin is an antibiotic used for the prevention of Mycobacterium avium complex (MAC) disease, a certain infection that is more likely to occur in people infected with HIV (AIDS).

  • What is the most important information I should know about Mycobutin?

    Do not take Mycobutin if you have active tuberculosis (a bacterial infection that affects the lungs).

    Mycobutin can cause blood problems, such as a decrease in neutrophils (a type of blood cell that fights infections) or platelets (type of blood cells that form clots to help stop bleeding). Your doctor will monitor your blood to check your blood cell counts.

    Urine, feces, saliva, sputum, sweat, tears, and skin can be colored brown-orange with Mycobutin. Soft contact lenses can also be permanently stained.

    Mild diarrhea is common with antibiotic use. However, a more serious form of diarrhea, although rare, may occur. Contact your doctor immediately if you experience stomach pain or cramps, severe diarrhea, or bloody stools. Do not treat the diarrhea without first checking with your doctor.

  • Who should not take Mycobutin?

    Do not take Mycobutin if you are allergic to it or any of its ingredients.

  • What should I tell my doctor before I take the first dose of Mycobutin?

    Tell your doctor about all prescription, over-the-counter, and herbal medications you are taking before beginning treatment with Mycobutin. Also, talk to your doctor about your complete medical history, especially if you have kidney disease, blood disorders, active tuberculosis, are pregnant, plan to become pregnant, or are breastfeeding.

  • What is the usual dosage?

    The information below is based on the dosage guidelines your doctor uses. Depending on your condition and medical history, your doctor may prescribe a different regimen. Do not change the dosage or stop taking your medication without your doctor's approval.

    Adults: The recommended dose is 300 milligrams (mg) once a day.

    If you have kidney impairment, your doctor will adjust your dose appropriately.

  • How should I take Mycobutin?

    Take Mycobutin exactly as prescribed by your doctor. You can take Mycobutin with food (such as applesauce) to prevent stomach upset. Your doctor may give you a lower dose if you have a tendency to develop nausea, vomiting, or stomach upset while you are taking Mycobutin.

  • What should I avoid while taking Mycobutin?

    Do not miss your scheduled follow-up appointments with your doctor.

  • What are possible food and drug interactions associated with Mycobutin?

    If Mycobutin is taken with certain other drugs, the effects of either could be increased, decreased, or altered. It is especially important to check with your doctor before combining Mycobutin with the following: birth control pills, clarithromycin, delavirdine, fluconazole, indinavir, itraconazole, nelfinavir, rifampin, ritonavir, or saquinavir.

  • What are the possible side effects of Mycobutin?

    Side effects cannot be anticipated. If any develop or change in intensity, tell your doctor as soon as possible. Only your doctor can determine if it is safe for you to continue taking this drug.

    Side effects may include: abdominal pain, diarrhea, fever, headache, nausea, rash, urine discoloration

  • Can I receive Mycobutin if I am pregnant or breastfeeding?

    The effects of Mycobutin during pregnancy and breastfeeding are unknown. Tell your doctor immediately if you are pregnant, plan to become pregnant, or are breastfeeding.

  • What should I do if I miss a dose of Mycobutin?

    If you miss a dose of Mycobutin, take it as soon as you remember. However, if it is almost time for your next dose, skip the one you missed and return to your regular dosing schedule. Do not take two doses at once.

  • How should I store Mycobutin?

    Store at room temperature.