Generic Name: Busulfan

  • What is Myleran?

    Myleran is a medicine used for the palliative treatment (to relieve the discomfort, symptoms, and stress of serious illness) of chronic (long-term) myelogenous (myeloid, myelocytic, and granulocytic) leukemia.

  • What is the most important information I should know about Myleran?

    Myleran can cause a severe decrease in the production of white blood cell, red blood cell, and platelet (type of blood cells that form clots to help stop bleeding) counts.

    Myleran can increase your risk of developing cancer.

    Myleran can decrease the hormone levels produced by the ovaries, cause absence of menstrual periods, and cause infertility, seizures, and liver, heart, or severe lung problems.

    Tell your doctor immediately if you experience abnormal darkening of your skin, bleeding, congestion, difficulty breathing, fever, loss of appetite, nausea and vomiting, persistent cough, sudden weakness, unusual tiredness, or weight loss while you are taking Myleran.

    Your doctor will be performing regular blood work to check your blood counts.

  • Who should not take Myleran?

    Do not take Myleran if you are allergic to it or any of its ingredients.

  • What should I tell my doctor before I take the first dose of Myleran?

    Tell your doctor about all prescription, over-the-counter, and herbal medications you are taking before beginning treatment with Myleran. Also, talk to your doctor about your complete medical history, especially if you have a history of blood disorders; head trauma; heart problems; kidney, liver, or lung disease; seizures; prior use of irradiation or chemotherapy; bone marrow suppression; or are pregnant, plan to become pregnant, or are breastfeeding.

  • What is the usual dosage?

    The information below is based on the dosage guidelines your doctor uses. Depending on your condition and medical history, your doctor may prescribe a different regimen. Do not change the dosage or stop taking your medication without your doctor's approval.

    Adults and children: Your doctor will prescribe the appropriate dose for you or your child based on the weight and height.

  • How should I take Myleran?

    Take Myleran exactly as prescribed by your doctor. Do not take extra doses or take more often without asking your doctor.

    Do not take Myleran without medical supervision.

  • What should I avoid while taking Myleran?

    Do not miss your follow-up appointments with your doctor.

    Do not become pregnant while you are taking Myleran.

  • What are possible food and drug interactions associated with Myleran?

    If Myleran is taken with certain other drugs, the effects of either could be increased, decreased, or altered. It is especially important to check with your doctor before combining Myleran with the following: cyclophosphamide, itraconazole, or phenytoin.

  • What are the possible side effects of Myleran?

    Side effects cannot be anticipated. If any develop or change in intensity, tell your doctor as soon as possible. Only your doctor can determine if it is safe for you to continue taking this drug.

    Side effects may include: abnormal darkening of your skin, allergic reactions, cataracts (clouding of the eye's lens), cough, fever, headache, itching, loss of appetite, lung disease, nausea, pain, rash, severe blood disorders, stomach enlargement, swelling, vomiting, weakness, weight loss

  • Can I receive Myleran if I am pregnant or breastfeeding?

    Myleran may cause harm to your unborn baby if you take it while you are pregnant. The effects of Myleran during breastfeeding are unknown. Tell your doctor immediately if you are pregnant, plan to become pregnant, or are breastfeeding.

  • What should I do if I miss a dose of Myleran?

    If you miss a dose of Myleran, take it as soon as you remember. However, if it is almost time for your next dose, skip the one you missed and return to your regular dosing schedule. Do not take two doses at once.

  • How should I store Myleran?

    Store at room temperature.