Generic Name: Primidone

  • What is Mysoline?

    Mysoline is a medication that is used to help control seizures. Mysoline may be taken alone or in combination with other medications to treat grand mal, psychomotor, and focal epileptic type seizures.
  • What is the most important information I should know about Mysoline?

    You should not suddenly stop taking Mysoline unless your doctor instructs you to as this may cause you to experience seizures. Mysoline may take several weeks to reach its full effect.
  • Who should not take Mysoline?

    You should not take Mysoline if you have a disorder known as "porphyria" or if you are allergic or sensitive to phenobarbital or any ingredient in Mysoline.
  • What should I tell my doctor before I take the first dose of Mysoline?

    Tell your doctor about all prescription, over-the-counter, and herbal medications you are taking before beginning treatment with Mysoline. Also, talk to your doctor about your complete medical history, especially if you are pregnant, plan to become pregnant, are breastfeeding, or are taking any other type of anti-seizure medications.
  • What is the usual dosage?

    The information below is based on the dosage guidelines your doctor uses. Depending on your condition and medical history, your doctor may prescribe a different regimen. Do not change the dosage or stop taking your medication without your doctor's approval.

    Adults and children ages 8 and older:

    Patients who are not taking other seizure medications: The initial daily dosage is as follows: Days 1-3, take 100-125 milligrams (mg) at bedtime; Days 4-6, take 100-125 mg twice daily; Days 7-9, take 100-125 mg three times daily; Day 10 and on for maintenance, 250 mg taken 3-4 times daily. Daily doses should not exceed 500 mg taken 4 times daily

    Patients who are not taking other seizure medications: The usual starting dose is 100-125 mg taken at bedtime, and the dose is then gradually increased as the dose of the other medication is gradually decreased over the course of several weeks.

    Children age 8 and younger: The initial daily dosage is as follows: Days 1-3; take 50 mg at bedtime; Days 4-6; take 50 mg twice daily; Days 7-9 take 100 mg twice daily; Day 10 and on for maintenance; 125- 250 mg taken 3 times daily.

  • How should I take Mysoline?

    Mysoline should be taken at the same time every day and can be taken with or without food.
  • What should I avoid while taking Mysoline?

    You should avoid suddenly stopping Mysoline therapy unless your doctor instructs you to.
  • What are possible food and drug interactions associated with Mysoline?

    If Mysoline is taken with certain other drugs, the effects of either could be increased, decreased, or altered. It is especially important to check with your doctor before combining Mysoline with any other medications.
  • What are the possible side effects of Mysoline?

    Side effects cannot be anticipated. If any develop or change in intensity, tell your doctor as soon as possible. Only your doctor can determine if it is safe for you to continue taking this drug.

    Side effects may include: unstable balance, dizziness, nausea, vomiting, irritability, loss of appetite, mood swings, sexual dysfunction, drowsiness, or blistering rash.

  • Can I receive Mysoline if I am pregnant or breastfeeding?

    The effects of Mysoline during pregnancy are unknown. Tell your doctor immediately if you are pregnant or plan to become pregnant. Mysoline is excreted in breast milk; you should not breastfeed while taking Mysoline unless otherwise instructed by your doctor.
  • What should I do if I miss a dose of Mysoline?

    If you miss a dose of Mysoline, do not double your next dose. Skip the dose you missed and return to your normal dosing schedule.
  • How should I store Mysoline?

    Mysoline should be stored at room temperature