Generic Name: Dienogest

  • What is Natazia?

    Natazia is an oral contraceptive, or birth control pill, used to prevent pregnancy.

  • What is the most important information I should know about Natazia?

    Do not use Natazia if you smoke cigarettes and are over 35 years old. Smoking increases your risk of serious cardiovascular side effects (heart and blood vessel problems) from birth control pills, including death from heart attack, blood clots or stroke. This risk increases with age and the number of cigarettes you smoke.

    Like pregnancy, birth control pills increase the risk of serious blood clots, especially in women who have other risk factors, such as smoking, obesity, or age greater than 35. It is possible to die from a problem caused by a blood clot, such as a heart attack or stroke. Some examples of serious blood clots are blood clots in the legs, lungs (pulmonary embolus), eyes (loss of eyesight), heart (heart attack), or brain (stroke). A few women who take birth control pills may get high blood pressure, gallbladder problems, or rare cancerous or noncancerous liver tumors. All of these events are uncommon in healthy women.

    Natazia does not protect against HIV infection (AIDS) and other sexually transmitted diseases.

    You may experience breakthrough bleeding or spotting while taking oral contraceptives, especially during the first 3 months of use. You may also have irregular periods. If you have missed more than two periods in a row or miss one period when you have not taken your birth control pills according to directions, call your doctor. Natazia should not be used in women who are pregnant.

    Call your doctor right away if you have persistent leg pain, sudden shortness of breath, sudden blindness that is partial or complete, severe pain in your chest, sudden or severe headache unlike your usual headaches, weakness or numbness in an arm or leg, trouble speaking, yellowing of the skin or eyes, or any thoughts of harming yourself.

  • Who should not take Natazia?

    Do not use Natazia if you smoke cigarettes and are over 35 years old or are pregnant.

    Do not take Natazia if you have ever had breast cancer or any cancer that is sensitive to female hormones; liver disease, including liver tumors; blood clots in your arms, legs, or lungs; stroke or heart attack, certain heart valve problems or heart rhythm abnormalities that can cause blood clots to form in the heart; an inherited problem with your blood that makes it clot more than normal; high blood pressure that medicine can't control; diabetes with kidney, eye, or blood vessel damage; certain kinds of severe migraine headaches with aura, numbness, weakness, or changes in vision.

    Birth control pills may not be a good choice for you if you have ever had jaundice (yellowing of the skin or eyes) caused by pregnancy (also called cholestasis of pregnancy).

    Natazia should not be used in women who have not had their first period or in postmenopausal women.

  • What should I tell my doctor before I take the first dose of Natazia?

    Tell your doctor if you have ever had any health conditions (especially those listed above) and also about all prescription, over-the-counter, and herbal medications you are taking before beginning treatment with Natazia. Also, talk to your doctor about your complete medical history, especially if you have or had high blood pressure, high cholesterol or triglycerides (or a family history of high triglycerides), migraines or other headaches, history of irregular menstrual bleeding or periods, depression, blotchy darkening of the skin (especially on the face, known as chloasma), will undergo surgery, wear contact lenses, smoke, are pregnant, or might be pregnant, plan to become pregnant, or are breastfeeding.

  • What is the usual dosage?

    The information below is based on the dosage guidelines your doctor uses. Depending on your condition and medical history, your doctor may prescribe a different regimen. Do not change the dosage or stop taking your medication without your doctor's approval.

    Adults: Each dark yellow tablet contains 3 milligrams (mg) of estradiol valerate. Each red tablet contains 2 mg of estradiol valerate and 2 mg of dienogest. Each light yellow tablet contains 2 mg of estradiol valerate and 3 mg of dienogest. Each dark red tablet contains 1 mg of estradiol valerate. Each inert white tablet contains inactive ingredients.

    Take the first dark yellow pill on the first day (Day 1) and one on the second day. Take one medium red tablet per day on Days 3 to 7. Take one light yellow tablet per day on Days 8 to 24. Take one dark red tablet per day on Days 25 and 26. Take one white inert tablet on Days 27 and 28. After all 28 tablets have been taken, start taking the first dark yellow pill from a new blister pack the very next day whether or not you are having your period.

  • How should I take Natazia?

    Before you start taking Natazia, be sure to read the directions. You should take Natazia once daily at the same time every day until the pack is empty. Take the pills in the order directed on the blister pack.

    Use a nonhormonal back-up method such as a condom or spermicide for the first 9 days you take Natazia.

  • What should I avoid while taking Natazia?

    Avoid smoking while taking Natazia. Also, avoid becoming pregnant while taking Natazia.

    Do not skip pills or delay taking your pill by more than 12 hours. If you miss pills (including starting the pack late), you could become pregnant. The more pills you miss, the more likely you are to get pregnant.

    Do not skip pills even if you do not have sex very often.

    You may feel sick to your stomach (nauseous), especially during the first few months that you take Natazia. If you feel sick to your stomach, do not stop taking the pills. The problem will usually go away. If your nausea doesn't go away, call your doctor.

  • What are possible food and drug interactions associated with Natazia?

    If Natazia is taken with certain other drugs, the effects of either could be increased, decreased, or altered. It is especially important to check with your doctor before combining Natazia with the following: antibiotics, antifungals, barbiturates, bosentan, carbamazepine, cimetidine, diltiazem, erythromycin, felbamate, grapefruit juice, griseofulvin, certain medicines used to treat HIV and AIDs such as protease inhibitors, ketoconazole, lamotrigine, oxcarbazepine, macrolides, phenytoin, rifampicin, St. John's wort, topiramate, and verapamil.

  • What are the possible side effects of Natazia?

    Side effects cannot be anticipated. If any develop or change in intensity, tell your doctor as soon as possible. Only your doctor can determine if it is safe for you to continue taking this drug.

    Side effects may include: spotting or bleeding between menstrual periods, headache, breast pain, discomfort or tenderness, nausea, vomiting, acne, increased weight

  • Can I receive Natazia if I am pregnant or breastfeeding?

    Oral contraceptives should not be used if you are pregnant or breastfeeding.

  • What should I do if I miss a dose of Natazia?

    If you miss a tablet, take the missed dose as soon as you remember if you are less than 12 hours late taking your pill. However, if you miss one pill for more than 12 hours or miss two pills or more, consult the patient information that accompanied your prescription or call your doctor or pharmacist for advice.

  • How should I store Natazia?

    Store at room temperature.

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