Neomycin sulfate

Generic Name: Neomycin

  • What is Neomycin sulfate?

    Neomycin is an antibiotic used with other medicines to suppress the normal bacteria of your intestines to prepare it for surgery. Also, neomycin is used with other medicines to reduce the ammonia-forming bacteria in the intestinal tract for the treatment of hepatic coma (a neurologic disorder caused by the accumulation of harmful substances, such as ammonia, in your blood due to liver failure). Neomycin may also be used to treat other conditions, as determined by your doctor.

  • What is the most important information I should know about Neomycin sulfate?

    Neomycin can cause harm to your nervous system, including problems with your hearing and balance. This can also cause numbness, skin tingling, muscle twitching, or seizures. Your risk can increase with impaired kidney function. Tell your doctor immediately if you experience dizziness, ringing or roaring in your ear, or any changes in your hearing.

    Neomycin can cause kidney problems. Your doctor will monitor your kidney function.

    Muscle weakness and decreased lung function can occur while receiving neomycin. Your risk can increase if you are taking neomycin with medications used for anesthesia or muscle relaxants.

    Neomycin can harm your unborn baby if you take it during pregnancy. Tell your doctor immediately if you are pregnant or plan to become pregnant.

    Use neomycin as prescribed by your doctor for the full course of treatment, even if symptoms improve earlier. Do not skip doses. Complete the full course of neomycin treatment. Skipping doses or not completing the full course of neomycin can decrease its effectiveness and can lead to the growth of bacteria that are resistant to the effects of neomycin.

  • Who should not take Neomycin sulfate?

    Do not take neomycin if you are allergic to it, any of its ingredients, or similar antibiotics (such as amikacin, streptomycin, or tobramycin).

    Do not take neomycin if you have intestinal obstruction and inflammatory or ulcerative disease of your stomach or intestines.

    Do not take neomycin to treat viral infections, such as the common cold.

  • What should I tell my doctor before I take the first dose of Neomycin sulfate?

    Tell your doctor about all prescription, over-the-counter, and herbal medications you are taking before beginning treatment with neomycin. Also, talk to your doctor about your complete medical history, especially if you have allergies; kidney disease; stomach or intestinal problems; muscular disorders, such as myasthenia gravis (a disease characterized by long-lasting fatigue and muscle weakness) or Parkinson's disease; or are pregnant or plan to become pregnant.

  • What is the usual dosage?

    The information below is based on the dosage guidelines your doctor uses. Depending on your condition and medical history, your doctor may prescribe a different regimen. Do not change the dosage or stop taking your medication without your doctor's approval.

    Intestinal Preparation for Surgery

    Adults ≥18 years: The recommended dose is 1 gram (g) once, given on the day before surgery.

    Hepatic Coma

    Adults ≥18 years: The recommended dose is 4-12 grams (g) per day, given in divided doses over 5-6 days.

  • How should I take Neomycin sulfate?

    Take neomycin exactly as prescribed by your doctor. Do not stop taking neomycin without speaking to your doctor, even if your symptoms improve earlier in the course of therapy.

  • What should I avoid while taking Neomycin sulfate?

    Do not take neomycin with other similar antibiotics that can cause hearing or kidney problems.

    Do not miss your scheduled follow-up appointments with your doctor.

  • What are possible food and drug interactions associated with Neomycin sulfate?

    If neomycin is taken with certain other drugs, the effects of either could be increased, decreased, or altered. It is especially important to check with your doctor before combining neomycin with the following: 5-fluorouracil, cisplatin, digoxin, diuretics (water pills) (such as ethacrynic acid or furosemide), methotrexate, other antibiotics that can harm your brain function or kidneys (such as amikacin, amphotericin B, bacitracin, colistin, paromomycin, polymyxin B, streptomycin, tobramycin, vancomycin, or viomycin), penicillin V, vitamin B12, or warfarin.

  • What are the possible side effects of Neomycin sulfate?

    Side effects cannot be anticipated. If any develop or change in intensity, tell your doctor as soon as possible. Only your doctor can determine if it is safe for you to continue taking this drug.

    Side effects may include: breathing problems, changes in your hearing, decreased urination, diarrhea, dizziness, hearing loss, increased fat in stool, itchiness, loss of balance, muscle twitching, nausea, numbness, ringing or roaring in your ear, seizures, skin tingling, vomiting

  • Can I receive Neomycin sulfate if I am pregnant or breastfeeding?

    Neomycin can harm your unborn baby if you take it during pregnancy. The effects of neomycin during breastfeeding are unknown. Tell your doctor immediately if you are pregnant, plan to become pregnant, or are breastfeeding.

  • What should I do if I miss a dose of Neomycin sulfate?

    If you miss a dose of neomycin, take it as soon as you remember. However, if it is almost time for your next dose, skip the one you missed and return to your regular dosing schedule. Do not take two doses at once.

  • How should I store Neomycin sulfate?

    Store at room temperature.