Generic Name: Pegfilgrastim

  • What is Neulasta?

    Neulasta is a man-made form of granulocyte colony-stimulating factor (G-CSF), which is made using the bacteria E. coli. G-CSF is a substance produced by the body. It stimulates the growth of neutrophils, a type of white blood cell important in the body's fight against infection.

    Neulasta is used to decrease the risk of infection caused by neutropenia, a condition where the body makes too few neutrophils, in people receiving anti-cancer therapy that has neutropenia as a side effect.

  • What is the most important information I should know about Neulasta?

    Occasionally pain and redness may occur at the injection site. If there is a lump, swelling, or bruising at the injection site that does not go away, talk to your doctor.

    Neulasta should only be injected on the day the doctor has determined and should not be injected until approximately 24 hours after receiving chemotherapy.

    The needle cover on the single-use prefilled syringe contains dry natural rubber (latex), which should not be handled by individuals sensitive to this substance.

  • Who should not take Neulasta?

    Do not take Neulasta if you have had a serious allergic reaction to Neulasta or to Neupogen (filgrastim).

  • What should I tell my doctor before I take the first dose of Neulasta?

    Tell your doctor about all prescription, over-the-counter, and herbal medications you are taking before beginning treatment with Neulasta. Also, talk to your doctor about your complete medical history, especially if you have a sickle cell disorder.

  • What is the usual dosage?

    The information below is based on the dosage guidelines your doctor uses. Depending on your condition and medical history, your doctor may prescribe a different regimen. Do not change the dosage or stop taking your medication without your doctor's approval.

    Adults: The recommended dose is 6 milligrams (mg) once per chemotherapy cycle. Do not administer between 14 days before and 24 hours after administration.

  • How should I take Neulasta?

    Neulasta is provided in a prefilled syringe. Neulasta should be stored in its carton to protect from light until use. If you are giving someone else Neulasta injections, it is important that you know how to inject Neulasta. Before getting your Neulasta injection, always check to see that: the name "Neulasta" appears on the carton and prefilled syringe label, the expiration date on the prefilled syringe has not passed, and that the Neulasta liquid is clear and colorless.

    This medicine comes with patient instructions. Read and follow these instructions carefully.

    Ask your doctor if you have any questions about the preparation, disposal, or administration of Neulasta.

  • What should I avoid while taking Neulasta?

    Follow your doctor's instructions about any restrictions on food, beverages, or activity while you are using Neulasta.

    Avoid shaking Neulasta.

  • What are possible food and drug interactions associated with Neulasta?

    No significant interactions have been reported with Neulasta at this time. However, always tell your doctor about any medicines you take, including over-the-counter drugs, vitamins, and herbal supplements.

  • What are the possible side effects of Neulasta?

    Side effects cannot be anticipated. If any develop or change in intensity, tell your doctor as soon as possible. Only your doctor can determine if it is safe for you to continue taking this drug.

    Side effects may include: aching in the bones and muscles

    Stop using Neulasta and call your doctor if you have any of these serious side effects: pain in the left upper stomach area or left shoulder tip area, shortness of breath, trouble breathing, a fast rate of breathing, wheezing, dizziness, swelling around the mouth or eyes, fast pulse, sweating, hives

  • Can I receive Neulasta if I am pregnant or breastfeeding?

    Neulasta has not been studied in pregnant women, and its effects on unborn babies are not known. If you take Neulasta while you are pregnant, it is possible that small amounts of it may get into your baby's blood. It is not known if Neulasta can get into human breast milk. If you are pregnant, think you may be pregnant, plan to become pregnant, or are breastfeeding, you should tell your doctor before using Neulasta.

  • What should I do if I miss a dose of Neulasta?

    If you miss a dose, contact your doctor or nurse.

  • How should I store Neulasta?

    Neulasta should be stored in the refrigerator, but not in the freezer. Protect Neulasta from light. If Neulasta is accidentally frozen, allow it to thaw in the refrigerator before injecting. However, if it is frozen a second time, do not use. Neulasta can be left at room temperature for up to 48 hours. Do not leave Neulasta in direct sunlight. For all questions about storage, contact your doctor, nurse or pharmacist.

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