What is Nexterone?Nexterone is a medicine used to treat and prevent frequently recurring ventricular arrhythmias (life-threatening irregular heartbeats) such as ventricular fibrillation or ventricular tachycardia with unstable blood circulation. Nexterone is used when other treatment did not work or was not tolerated, or in patients who cannot take oral medicines. Nexterone is administered intravenously (through a vein in your arm).
What is the most important information I should know about Nexterone?Nexterone can cause very low blood pressure; your doctor will monitor your blood pressure while you receive Nexterone.
Nexterone can cause a different type of abnormal heartbeat; which can be dangerous and life-threatening. Also, Nexterone can increase your risk of having very slow heartbeat, very low blood pressure, liver injury, lung disorders, vision problems, or thyroid abnormalities. Because of these possible side effects, Nexterone should be used in people with life-threatening arrhythmias for which other treatments did not work or were not tolerated.
Who should not take Nexterone?Your doctor will not administer Nexterone if you are allergic to it, any of its ingredients, iodine, if you have an abnormally slow heartbeat or heart block (unless you have a pacemaker), or if you have cardiogenic shock (a complication in which a suddenly weakened heart is not able to pump enough blood to meet the body's needs).
What should I tell my doctor before I take the first dose of Nexterone?Tell your doctor about all prescription, over-the-counter, and herbal medications you are taking before beginning treatment with Nexterone. Also, talk to your doctor about your complete medical history, especially if you have certain heart problems; blood pressure, lung, or breathing problems; liver or kidney injury; thyroid abnormalities; are pregnant, plan to become pregnant, or are breastfeeding.
What is the usual dosage?The information below is based on the dosage guidelines your doctor uses. Depending on your condition and medical history, your doctor may prescribe a different regimen. Do not change the dosage or stop taking your medication without your doctor's approval.
Adults: Your doctor will administer the appropriate dose for you based on your condition.
How should I take Nexterone?Your doctor will administer Nexterone to you.
What should I avoid while taking Nexterone?Do not miss your scheduled follow-up appointments with your doctor.
What are possible food and drug interactions associated with Nexterone?If Nexterone is used with certain other drugs, the effects of either could be increased, decreased, or altered. It is especially important to tell your doctor if you are taking any of the following prior to treatment with Nexterone: anti-HIV medications called protease inhibitors (such as indinavir), antihistamines (such as loratadine or cimetidine), blood pressure/heart medications known as beta-blockers (such as propranolol) or calcium channel blockers (such as diltiazem or verapamil), blood thinners (such as warfarin), certain antibiotics (such as erythromycin, moxifloxacin, or rifampin), certain antidepressants (such as trazodone), cholesterol medications (such as atorvastatin, cholestyramine, or simvastatin), clopidogrel, cyclosporine, dextromethorphan, digoxin, fentanyl, grapefruit juice, other antiarrhythmics (such as disopyramide, flecainide, procainamide, or quinidine), phenytoin, or St. John's wort.
What are the possible side effects of Nexterone?Side effects cannot be anticipated. If any develop or change in intensity, tell your doctor as soon as possible. Only your doctor can determine if it is safe for you to continue taking this drug.
Side effects may include: abnormal changes in your heartbeat, confusion, cough, fever, injection-site reactions (such as pain or redness), low blood pressure, nausea, rash, shortness of breath, visual disturbances, weakness
Can I receive Nexterone if I am pregnant or breastfeeding?The effects of Nexterone during pregnancy and breastfeeding are unknown. Nexterone can be found in your breast milk if you receive it while breastfeeding. Tell your doctor immediately if you are pregnant, plan to become pregnant, or are breastfeeding.
What should I do if I miss a dose of Nexterone?Nexterone should be given under special circumstances determined by your doctor.
How should I store Nexterone?Your doctor will store this medication for you.