Generic Name: Nitroglycerin

  • What is this medication and its most common uses?

    Nitrostat is a medicine used to relieve sudden chest pain or prevent chest pain associated with coronary artery disease (narrowing of the small blood vessels that supply blood and oxygen to the heart). Nitrostat is available as a sublingual tablet (dissolved under the tongue).

  • What should I know when beginning and continuing on this medication?

    How does this medication work?

    Nitrostat works by relaxing the blood vessels in your muscles, including your heart.

    What are the beneficial effects of this medication and when should I begin to have results?

    What: Nitrostat may help to reduce and/or prevent your chest pain.

    When: Nitrostat may start to work within a few minutes of taking a dose.

    How do I know it is working?

    You may feel an improvement in your chest pain after you take Nitrostat. This is a good indicator that the medicine is working. Your healthcare provider may ask you questions to assess how well your symptoms are controlled.

  • What are the possible side effects of this medication?

    The following is not a full list of side effects. Side effects cannot be anticipated. If any develop or change in intensity, tell your healthcare provider as soon as possible. Only your healthcare provider can determine if it is safe for you to continue taking this medication.

    More common side effects may include: headache, a spinning feeling, dizziness, weakness, fluttery or throbbing heartbeat, nausea, vomiting, sweating, paleness, fainting, flushing, rash.

    Less common side effects may include:

    Nitrostat may cause low blood pressure, a fast heartbeat, blurry vision, or dry mouth.

  • Who should not take this medication?

    Do not take Nitrostat if you are allergic to it or any of its ingredients.

    Do not take Nitrostat if you had a very recent heart attack, have severe anemia (low red blood cell counts), or if you have increased pressure in your head.

    Do not take Nitrostat with medicines for erectile dysfunction (an inability to attain or maintain an erection) (such as sildenafil, tadalafil, or vardenafil).

  • What should I tell my healthcare provider before I take the first dose of this medication?

    Tell your healthcare provider about all prescription, over-the-counter, and herbal medications you are taking before beginning treatment with Nitrostat. Also, talk to your healthcare provider about your complete medical history, especially if you have low blood pressure; heart problems (such as heart failure or a recent heart attack); or if you are pregnant, plan to become pregnant, or are breastfeeding.

  • What is the usual dosage?

    The information below is based on the dosage guidelines your healthcare provider uses. Depending on your condition and medical history, your healthcare provider may prescribe a different regimen. Do not change the dosage or stop taking your medication without your healthcare provider's approval.

    Adults: The recommended dose is 1 tablet at the first sign of chest pain. You may repeat the dose every 5 minutes, until the chest pain is relieved. If the pain continues after taking 3 tablets in a 15-minute period, or is different than you typically experience, call your healthcare provider or seek emergency help.

    Nitrostat may be used 5 to 10 minutes before engaging in activities that may cause chest pain, as directed by your healthcare provider.

  • How should I take this medication?

    Take Nitrostat exactly as prescribed by your healthcare provider. Do not change your dose without first talking to your healthcare provider.

    Dissolve Nitrostat under your tongue. Do not chew, crush, or swallow it.

    You may feel a burning or tingling sensation in your mouth when you take Nitrostat.

    You should sit down when you take Nitrostat and be careful when you stand up. This will help lower the risk of you falling due to lightheadedness or dizziness.

  • What should I avoid while taking this medication?

    Do not drink alcohol while you are taking Nitrostat.

  • What are the possible food and drug interactions associated with this medication?

    If Nitrostat is taken with certain other drugs, the effects of either could be increased, decreased, or altered. It is especially important to check with your healthcare provider before combining Nitrostat with the following: alcohol, alteplase, aspirin, blood pressure/heart medications (such as metoprolol or amlodipine), certain antidepressants (such as amitriptyline, desipramine, or doxepin), erectile dysfunction medicines, ergotamine, heparin, other similar medicines known as nitrates, or phenothiazines (such as chlorpromazine).

  • May I receive this medication if I am pregnant or breastfeeding?

    The effects of Nitrostat during pregnancy and breastfeeding are unknown. Tell your healthcare provider immediately if you are pregnant, plan to become pregnant, or are breastfeeding.

  • What should I do if I miss a dose of this medication?

    Nitrostat should be taken only as needed.

  • How should I store this medication?

    Store at room temperature in the original glass container, and tightly cap the container after each use.