Generic Name: Ketoconazole

  • What is Nizoral?

    Nizoral, is an antifungal drug used to treat several fungal infections within the body.

  • What is the most important information I should know about Nizoral?

    In some people, Nizoral may cause serious or even fatal damage to the liver. Before starting to take Nizoral, and at frequent intervals while you are taking it, you should have blood tests to evaluate your liver function. Tell your doctor immediately if you experience any signs or symptoms that could mean liver damage; these include unusual fatigue, loss of appetite, nausea or vomiting, yellowing of the eyes or skin, dark urine, or pale stools.

    In rare cases, people have had life-threatening allergic reactions after taking their first dose of Nizoral. Symptoms may include difficulty breathing; tightness in the chest; swelling of the eyelids, face, or lips; or rash or hives. If this happens, seek immediate medical care.

    Do not take more than the recommended dose or use for longer than prescribed without checking with your doctor.

    Nizoral only works against fungi; it does not treat viral infections (such as the common cold) or bacterial infections.

    Be sure to use Nizoral for the full course of treatment. If you do not, the medicine may not clear up your infection completely. The infection could also become less sensitive to this or other medicines. This could make the infection harder to treat in the future.

    Nizoral may increase the blood sugar-lowering effect of your diabetes medicine. Check blood sugar levels closely. Consult your doctor before changing the dose of your diabetes medicine.

  • Who should not take Nizoral?

    Do not take Nizoral if you are sensitive to it or have ever had an allergic reaction to it. Never take Nizoral together with astemizole, cisapride, terfenadine, or triazolam. Rare, but sometimes fatal reactions have been reported when these drugs are combined.

  • What should I tell my doctor before I take the first dose of Nizoral?

    Tell your doctor about all prescription, over-the-counter, and herbal medications you are taking before beginning treatment with Nizoral. Also, talk to your doctor about your complete medical history, especially if you have low stomach acid, a history of liver disease, blood problems, or if you regularly use, abuse or are dependent on alcohol.

  • What is the usual dosage?

    The information below is based on the dosage guidelines your doctor uses. Depending on your condition and medical history, your doctor may prescribe a different regimen. Do not change the dosage or stop taking your medication without your doctor's approval.

    Adults: The usual starting dose is a 200-milligram (mg) tablet once a day. In very serious infections or if you are unresponsive within the expected time, the dose of Nizoral may be increased to 400 mg (two tablets) once a day.

    Children >2 years: Your doctor will prescribe the appropriate dose for your child based on their body weight.

  • How should I take Nizoral?

    Nizoral can be taken with or without food. You may want to take Nizoral tablets with meals to avoid stomach upset.

    Do not take an antacid within 1 hour before or 2 hours after you take Nizoral.

  • What should I avoid while taking Nizoral?

    Avoid alcohol and do not take with antacids.

    Do not take more than the recommended dose or use for longer than prescribed without checking with your doctor.

    Do not take Nizoral if you are also taking astemizole, cisapride, terfenadine, or triazolam.

  • What are possible food and drug interactions associated with Nizoral?

    If Nizoral is taken with certain other drugs, the effects of either could be increased, decreased, or altered. It is especially important to check with your doctor before combining Nizoral with the following: alcohol, antacids, anticoagulants (blood thinners), anti-ulcer medications, astemizole, cisapride, cyclosporine, digoxin, isoniazid, methylprednisolone, midazolam, oral diabetes drugs, phenytoin, rifampin, tacrolimus, terfenadine, and triazolam.

  • What are the possible side effects of Nizoral?

    Side effects cannot be anticipated. If any develop or change in intensity, tell your doctor as soon as possible. Only your doctor can determine if it is safe for you to continue taking this drug.

    Side effects may include: nausea, vomiting, abdominal pain, itching

  • Can I receive Nizoral if I am pregnant or breastfeeding?

    The effects of Nizoral during pregnancy and breastfeeding are unknown. Tell your doctor immediately if you are pregnant, plan to become pregnant, or are breastfeeding.

  • What should I do if I miss a dose of Nizoral?

    Take the forgotten dose as soon as you remember. However, if it is almost time for your next dose, skip the one you missed and go back to your regular dosing schedule. Do not take two doses at once.

  • How should I store Nizoral?

    Store at room temperature.

Meet the Pharmacists

I'm Beth Isaac, PharmD. Welcome to PDR Health!

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